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Professor Deborah Watson-Jones

BMBCh MRCP DTM&H MSc PhD

Professor
(Clinical)

Mwanza Intervention Trials Unit
National Institute for Medical Research
P.O. Box 11936 Mwanza
Tanzania

Tel.
+255 754 056066 / +44 207927 2958

Fax.
+255 28 2500019

Debby Watson-Jones is a Clinical Epidemiologist who has lived and worked in Kenya, Nigeria, Senegal, India, Mongolia and Tanzania. She has worked for LSHTM since 1995 and is currently based in Tanzania.

Affiliations

Department of Clinical Research
Faculty of Infectious and Tropical Diseases

Centres

Maternal, Adolescent, Reproductive & Child Health (MARCH)
Vaccine Centre

Teaching

She is the co-organiser of Control of Reproductive Tract Infections Module (3192). She has also taught on the Vaccinology in Africa course.

Research

Her main research interest is the development and evaluation of interventions to control human papillomavirus (HPV), Ebola, HIV and other sexually transmitted infections in sub-Saharan Africa. She is currently leading EBOVAC1, a multisite project that is implementing several clinical trials to evaluate the Ad26.ZEBOV/MVA BN Filo heterologous prime boost vaccine to prevent Ebola infection, with trial sites in Sierra Leone. She is also leading the DoRIS trial to evaluate immunogenicity and safety of one dose of HPV vaccine in Tanzania. She is a member of the Single-Dose HPV Vaccine Evaluation Consortium, funded by the Bill & Melinda Gates Foundation and convened by PATH.

Recently completed studies include a project to collate lessons learnt from HPV vaccine demonstration projects in low and middle income countries and studies on HPV epidemiology, other STIs and the vaginal microbiome around sexual debut in Tanzania. Previous studies include a trial to compare different HPV vaccine delivery strategies in Tanzania; a phase IIIb immunogenicity and safety trial of the bivalent HPV vaccine in young African women; HPV vaccine acceptability in hard-to-reach populations in Kenya, PMTCT performance in East Africa, interventions against HSV-2 to prevent HIV infection, syphilis in pregnancy, hydatid disease in Kenya and Mongolia and HIV/STD control in large-scale goldmines and neighbouring communities in the Lake Victoria Goldfields. She was the LSHTM research team leader in Mwanza from 2003-2007.

She is an advisory committee member on one dose HPV vaccine trials and HPV therapeutic vaccines and a member of the WHO Working Group for the Preferred Product Characteristics for HSV vaccines. She was a member of the UK DOH Expert Panel on the prime boost vaccine, the LSHTM Ebola task force, the GAVI Alliance Independent Review Committee, the WHO  Committee for the revision of guidelines for comprehensive cancer control (C4-GEP) and a temporary advisor for the WHO HPV Vaccine Advisory Committee.

 

 

Research Area
Clinical trials
Sexual health
Vaccines
Adolescent health
Randomised controlled trials
Reproductive health
Discipline
Epidemiology
Medicine
Vaccinology
Disease and Health Conditions
Cancer
Herpesviruses
HIV/AIDS
Sexually transmitted disease
Syphilis
Cervical cancer
Emerging Infectious Disease
Human papillomavirus (HPV)
Sexually transmitted infection
Zoonotic disease
Country
Kenya
Sierra Leone
Tanzania
Uganda
South Africa
Zambia
Region
Sub-Saharan Africa (developing only)

Selected Publications

Human papillomavirus DNA detected in fingertip, oral and bathroom samples from unvaccinated adolescent girls in Tanzania.
Houlihan CF; Baisley K; Bravo IG; Pavón MA; Changalucha J; Kapiga S; De Sanjosé S; Ross DA; Hayes RJ; Watson-Jones D
2019
Sexually Transmitted Infections
Safety and Immunogenicity of a 2-Dose Heterologous Vaccination Regimen With Ad26.ZEBOV and MVA-BN-Filo Ebola Vaccines: 12-Month Data From a Phase 1 Randomized Clinical Trial in Uganda and Tanzania.
Anywaine Z; Whitworth H; Kaleebu P; Praygod G; Shukarev G; Manno D; Kapiga S; Grosskurth H; Kalluvya S; Bockstal V
2019
The Journal of infectious diseases
Review of the current published evidence on single-dose HPV vaccination 2nd Edition
Basu P; Brisson M; Campos N; Clarke E; Drolet M; Gallagher K; Henão R; Ana M; Howard N; Hutubessy R
2019
Enrolling study personnel in Ebola vaccine trials: from guidelines to practice in a non-epidemic context.
Lhomme E; Modet C; Augier A; Faye S; Dabakuyo-Yonli TS; Levy-Marchal C; D'Ortenzio E; Yazdanpanah Y; Chêne G; Beavogui AH
2019
TRIALS
HPV prevalence around the time of sexual debut in adolescent girls in Tanzania.
Baisley KJ; Andreasen A; Irani J; Nnko S; Changalucha J; Crucitti T; Francis S; Holm Hansen C; Hayes RJ; Buvé A
2019
Sexually Transmitted Infections
Prevention of Ebola virus disease through vaccination: where we are in 2018.
Lévy Y; Lane C; Piot P; Beavogui AH; Kieh M; Leigh B; Doumbia S; D'Ortenzio E; Lévy-Marchal C; Pierson J
2018
Lancet
Results from a cross-sectional sexual and reproductive health study among school girls in Tanzania: high prevalence of bacterial vaginosis.
Francis SC; Holm Hansen C; Irani J; Andreasen A; Baisley K; Jespers V; Crucitti T; Changalucha J; Hayes RJ; Nnko S
2018
Sexually transmitted infections
Vaccine programme stakeholder perspectives on a hypothetical single-dose human papillomavirus (HPV) vaccine schedule in low and middle-income countries.
Gallagher KE; Kelly H; Cocks N; Dixon S; Mounier-Jack S; Howard N; Watson-Jones D
2018
Papillomavirus research (Amsterdam, Netherlands)
See more Publications