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Dr Mateus Kambale Sahani

Research Assistant

London School of Hygiene & Tropical Medicine
15-17 Tavistock Place
London city
WC1H 9SH
United Kingdom

Research Fellow at LSHTM from March 2020 to March 2026, then Research Assistant from May 2026 to present. Medical Doctor (MD) and Global/Public Health Specialist (MSc, PhD).

Clinician for more than 20 years and Global Health Specialist for 8 years, I have been working in clinical settings in different countries including the Democratic Republic of Congo (DRC) and Rwanda. As clinician and researcher for both clinical research and public health research projects, I am familiar with different concepts such as incubation periods, latent period, epidemic curve, attack rate, herd immunity, surveillance, etc. Community Engagement and Involvement (CEI) Specialist for more than 12 years. I was responsible of developing and implementing the CEI strategies for all the clinical trials that I was managing in different countries (M/XDR-TB in Tashkent/Uzbekistan, Yellow Fever Vaccine, fractional dose study in Mbarara/Uganda, Yellow Fever Vaccine, dose finding study in Mbarara/Uganda, Ebola vaccine Efficacy and Safety study in Mbarara/Uganda, Ebola vaccine Immunogenicity and Safety study in Goma city/Democratic Republic of Congo (DRC), Moxidectin trial for Onchocerciasis treatment in Ituri/DRC. My PhD at LSHTM was focused on Community Engagement and Involvement for the response to health crises in Madagascar. In addition, I was also involved in implementing public health research on Community Engagement and Involvement for the response to health crises in Uganda, Ethiopia, and Sierra-Leone.
I was involved in different aspects of clinical activities including infectious diseases control and surveillance. I have conducted research activities in both epidemiological field (including programme evaluation and monitoring) and clinical research including trial and non-trial. So far, I have managed 10 clinical trials with different organisations: LSHTM, MSF, Epicentre, Pharmalys, MDGH. The clinical trials were conducted diverse domain such as vaccine efficacy and effectiveness, drugs testing such as Tranexamic acid, MDR/XDR-TB new regimen for 6 months, Onchocerciasis new treatment (Moxidectin vs Ivermectin), Ivermectin vs Albendazole for Soil-Transmitted Helminths and scabies, etc. 

Affiliations

Department of Disease Control
Faculty of Infectious and Tropical Diseases

Teaching

  1. Personal Tutor of a MSc student for MSc Public Health (PHP); Supervisor of their Summar Project since September 2024.
  2. Personal Tutor of a MSc student for MSc Control of Infectious Diseases - CID (ITD) at LSHTM.
  3. Supervisor of their Summar Project since September 2024 at LSHTM.
  4. Seminar leader for PBL teaching on Applied Communicable Diseases Control (ACDC) Module at LSHTM.
  5.  Seminar leader (PGTA) in Disaster Risk Reduction at UCL. 

 

 

Coaching, tutorial, guidance, short course training, seminar, panelist in webinars, etc.

1. Co-supervisor of a MSc student for her research work for summer project.
2. Guest Lecturer with Wageningen University, Providing guest lecture to a class of 55 students at Wageningen University. Two times in 2023 and 2024.
3. Panelist in the webinar titled: Complex Emergencies "Syndemics" organised by EBODAC and LSHTM on 16 October 2020.
4. Panelist in the webinar titled: Vaccine Confidence in the Context of Trials, 30th July 2020; organised by LSHTM and EBODAC online.

Research

Global Health Research, Climate change, Humanitarian crisis, Epidemiological Research, Operational Research, Clinical Trials/Clinical Research, community health, community engagement, community involvement and response to health crisis, health impact of programmes. Any Global Health or Clinical topics.

Research Area
Global Health
Environmental Health
Child health
Adolescent health
Health impact analysis
Health outcomes
Health sector development
Epidemiology
Nutrition
Operational research
Policy analysis
Inclusive community development
AMR (Antimicrobial resistance)
Clinical research
Health services research
Health in humanitarian crises
Natural disasters
Clinical trials
Parasitology
Disease and Health Conditions
Pandemic diseases
Emerging infectious diseases
Infectious diseases
Non-communicable diseases
Country
United Kingdom
Democratic Republic of the Congo
Kenya
Uganda
Madagascar
Ethiopia
Sierra Leone
Tanzania
Ghana
Region
European Union
Sub-Saharan Africa (all income levels)
East Asia & Pacific (all income levels)

Selected Publications

Examining the effects of climate and environmental hazards on vector and water‑borne diseases in Eastern Uganda
SAHANI, MK; Twinomuhangi, R; Sseviiri, H; Susannah H, M;
2026
Discover Environment
Examining the effects of climate and environmental hazards on vector and water-borne diseases in Eastern Uganda.
Twinomuhangi, R; Sseviiri, H; MAYHEW, SH; PARES Research Group,; SAHANI, MK;
2026
Discover Environment
Engaging communities as partners in health crisis response: a realist-informed scoping review for research and policy.
SAHANI, MK; Maat, H; BALABANOVA, D; Woldie, M; Richards, P; PARES Research Group,; Mayhew, S;
2024
Health Research Policy and Systems
Perceptions, attitudes, and willingness of healthcare and frontline workers to participate in an Ebola vaccine trial in Uganda.
Kimbugwe, G; Vatrinet, R; Mwanga, JA; Kakuru, R; Mpeirwe, D; Logoose, S; Opio, K; Kambale, M; SEELEY, J; Grais, RF; Marquer, C; KALEEBU, P; SSALI, A;
2024
Vaccine
Immunogenicity and safety of fractional doses of 17D-213 yellow fever vaccine in children (YEFE): a randomised, double-blind, non-inferiority substudy of a phase 4 trial.
Juan-Giner, A; Namulwana, ML; Kimathi, D; Grantz, KH; Fall, G; Dia, M; Bob, NS; Sall, AA; Nerima, C; SAHANI, MK; Mulogo, EM; Ampeire, I; Hombach, J; Nanjebe, D; Mwanga-Amumpaire, J; Cummings, DA T; Bejon, P; Warimwe, GM; Grais, RF;
2023
The Lancet. Infectious diseases
EBOLA DISEASE IN DRC: CHALLENGE FOR RECURRENT DEVELOPMENT
SAHANI, M;
2023
Engaging communities as partners in health crisis response: a best-practice framework for researchers
SAHANI, MK; Susannah, M; Dina, B; And, C;
2022
The Global Health Network Conference in Cape Town/ South Africa
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