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Dr Chrissy Roberts

PhD AFHEA

Associate Professor
of Human Genetics

Room
Room 307

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
+44 (0) 20 7 927 2913

I am an associate professor in the Department of Clinical Research and a member of the trachoma group. My research focuses on the genomic and immunogenetic correlates of diseases that affect people living in Sub-Saharan Africa, the Pacific Islands and other low and middle income countries. I joined the LSHTM Clinical Research Department in 2009 after spending several years researching the use advanced diagnostics approaches to improve the outcome of stem cell transplants at the UCL Cancer Institute and Anthony Nolan Research Institute. Much of my recent work has focussed on trachoma (the leading infectious cause of blindness) but my diverse research interests include both communicable and non-communicable diseases. I take a multidisciplinary approach to research and have expertise in molecular genetics, diagnostics, genomics, computer and data sciences, biostatistics, bioinformatics, field survey methods and genetic epidemiology. 

I am chair of the Open Data Kit @ LSHTM working group, which provides electronic data collection services. The ODK@LSHTM service has been set up to help scientific researchers use ODK in their projects. This service is available on a pay-what-you-can basis to anyone undertaking bona-fide research that can benefit global health, including studies focussed on human health, one-health, environmental and ecological research; as well as public health interventions, outbreak response and clinical trials. For more information, please visit odk.lshtm.ac.uk

 

Affiliations

Department of Clinical Research

Teaching

I have extensive teaching experience and I am involved in the LSHTM taught course and distance learning programme as well as supervising and mentoring research degree students. I am currently the Module Organiser for the Distance Learning Module IDM-102 : Principles of Biology.

Research

Research Area
Diagnostics
Human genetics
Innate immunity
Immunisation
Methodology
Mixed methods
Mobile technologies
Discipline
Genetic epidemiology
Genomics
Biochemistry
Genetics
Immunology
Microbiology
Molecular biology
Opthalmology
Disease and Health Conditions
Cancer
Eye diseases
Infectious disease
Leprosy
Trachoma
Blindness
Neglected Tropical Diseases (NTDs)
Sexually transmitted infection
Skin disease
Tropical diseases
Country
Gambia, The
Guinea-Bissau
Senegal
Tanzania
Region
Sub-Saharan Africa (developing only)

Selected Publications

Differential frequency of NKG2C/KLRC2 deletion in distinct African populations and susceptibility to Trachoma: a new method for imputation of KLRC2 genotypes from SNP genotyping data.
Goncalves, A.; Makalo, P.; Joof, H.; Burr, S.; Ramadhani, A.; Massae, P.; Malisa, A.; Mtuy, T.; Derrick, T.; Last, A.R.; Nabicassa, M.; Cassama, E.; Houghton, J.; Palmer, C.D.; Pickering, H.; Burton, M.J.; Mabey, D.C.; Bailey, R.L.; Goodier, M.R.; Holland, M.J.; Roberts, C.H.;
2016
Hum Genet
Conjunctival fibrosis and the innate barriers to Chlamydia trachomatis intracellular infection: a genome wide association study.
Roberts, C.H. ; Franklin, C.S. ; Makalo, P. ; Joof, H. ; Sarr, I. ; Mahdi, O.S. ; Sillah, A. ; Bah, M. ; Payne, F. ; Jeffreys, A.E. ; Bottomley, W. ; Natividad, A. ; Molina-Gonzalez, S. ; Burr, S.E. ; Preston, M. ; Kwiatkowski, D. ; Rockett, K.A. ; Clark, T.G. ; Burton, M.J. ; Mabey, D.C. ; Bailey, R. ; Barroso, I. ; Holland, M.J. ;
2015
Sci Rep
Killer-cell Immunoglobulin-like Receptor gene linkage and copy number variation analysis by droplet digital PCR.
Roberts, C.H. ; Jiang, W. ; Jayaraman, J. ; Trowsdale, J. ; Holland, M.J. ; Traherne, J.A. ;
2014
Genome Med
Conjunctival Scarring in Trachoma Is Associated with the HLA-C Ligand of KIR and Is Exacerbated by Heterozygosity at KIR2DL2/KIR2DL3.
Roberts, C.H. ; Molina, S. ; Makalo, P. ; Joof, H. ; Harding-Esch, E.M. ; Burr, S.E. ; Mabey, D.C. ; Bailey, R.L. ; Burton, M.J. ; Holland, M.J. ;
2014
PLoS Negl Trop Dis
Eyescores: an open platform for secure electronic data and photographic evidence collection in ophthalmological field studies.
Roberts, C.H.; Mtuy, T.; Derrick, T.; Burton, M.J.; Holland, M.J.;
2013
Br J Ophthalmol
Development and Evaluation of a Next-Generation Digital PCR Diagnostic Assay for Ocular Chlamydia trachomatis Infections.
Roberts, C.H. ; Last, A. ; Molina-Gonzalez, S. ; Cassama, E. ; Butcher, R. ; Nabicassa, M. ; McCarthy, E. ; Burr, S.E. ; Mabey, D.C. ; Bailey, R.L. ; Holland, M.J. ;
2013
J Clin Microbiol
Plasmid copy number and disease severity in naturally occurring ocular Chlamydia trachomatis infection.
Last, A.R.; Roberts, C.H.; Cassama, E.; Nabicassa, M.; Molina-Gonzalez, S.; Burr, S.E.; Mabey, D.C.; Bailey, R.L.; Holland, M.J.;
2013
J Clin Microbiol
See all Dr Chrissy Roberts's Publications