Dr Chrissy Roberts


Associate Professor
of Human Genetics

Room 307

Keppel Street
United Kingdom

+44 (0) 20 7 927 2913

I am an associate professor in the Department of Clinical Research, a member of the LSHTM trachoma group, data & laboratories lead for the FIEBRE study and academic lead of the LSHTM Open Research Kits.

My research focuses on understanding the epidemiology of disease through the combined use of emerging technologies, novel diagostics, data science, field studies and laboratory testing. 

I take a multidisciplinary approach to research and have expertise in molecular genetics, diagnostics, genomics, computer and data sciences, biostatistics, bioinformatics, field survey methods and genetic epidemiology. 




Department of Clinical Research


I have extensive teaching experience and I am involved in the LSHTM taught course and distance learning programme as well as supervising and mentoring research degree students.

I am the Module Organiser for the Distance Learning Module IDM-102 : Principles of Biology.

Along with my colleagues Michael Marks & Matthew MacGregor, I was the recipient of the  2017 LSHTM Director's Award for Excellence and innovation in the use of technology to enhance learning.



Current and Recent Grant Funded Research

FIEBRE: Febrile Illness Etiology in a Broad Range of Endemicity

Funder : Department for International Development (London, United Kingdom)

Dates : 2017-04 to 2021-03

Role : Co-Investigator


Extended Mapping of trachoma in the Western Pacific

Funder : Fred Hollows Foundation (Melbourne, Australia)

Dates 2015-05 to 2019-12

Role : Co-Principal Investigator (with David Mabey) 

Prevalence and Risk Factors for Helminths and Intestinal Protozoa in UAE

Funder : United Arab Emirates University (Abu Dhabi, United Arab Emirates)

Dates : 2017-01 to 2018-12

Role : Co-Investigator


Droplet digital PCR for evaluation of associations between human herpesvirus infection and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

Funder : National Institutes of Health (MD, MD, United States)

Dates : 2016-01 to 2018-06

Role : Co-Investigator


Is trachomatous inflammation associated with conjunctival Chlamydia trachomatis infection in the Pacific Islands where blinding trachomatous trichiasis is rare?

Funder : Coalition for Operational Research on NTDs (COR-NTD) (Atlanta, Georgia, United States)

Dates : 2017-01 to 2017-12

Role : Co-Principal Investigator (with David Mabey)


Solving the Clinical Enigma of trachoma in the Solomon Islands

Funder : Fred Hollows Foundation (Melbourne, Australia)

Dates : 2013-03 to 2015-02

Role : Principal Investigator (Succeeding Anthony Solomon)

Research Area
Human genetics
Innate immunity
Mixed methods
Mobile technologies
Genetic epidemiology
Molecular biology
Disease and Health Conditions
Eye diseases
Infectious disease
Neglected Tropical Diseases (NTDs)
Sexually transmitted infection
Skin disease
Tropical diseases
Gambia, The
Sub-Saharan Africa (developing only)

Selected Publications

Population-based analysis of ocular Chlamydia trachomatis in trachoma-endemic West African communities identifies genomic markers of disease severity.
Last, A.R. ; Pickering, H. ; Roberts, C.H. ; Coll, F. ; Phelan, J. ; Burr, S.E. ; Cassama, E. ; Nabicassa, M. ; Seth-Smith, H.M.B. ; Hadfield, J. ; Cutcliffe, L.T. ; Clarke, I.N. ; Mabey, D.C.W. ; Bailey, R.L. ; Clark, T.G. ; Thomson, N.R. ; Holland, M.J. ;
Genome Med
Clinical signs of trachoma are prevalent among Solomon Islanders who have no persistent markers of prior infection with Chlamydia trachomatis.
Butcher, R. ; Sokana, O. ; Jack, K. ; Sui, L. ; Russell, C. ; Last, A. ; Martin, D.L. ; Burton, M.J. ; Solomon, A.W. ; Mabey, D.C.W. ; Roberts, C.H. ;
Wellcome Open Res
Oral doxycycline for the prevention of postoperative trachomatous trichiasis in Ethiopia: a randomised, double-blind, placebo-controlled trial.
Habtamu, E. ; Wondie, T. ; Aweke, S. ; Tadesse, Z. ; Zerihun, M. ; Gashaw, B. ; Roberts, C.H. ; Kello, A.B. ; Mabey, D.C.W. ; Rajak, S.N. ; Callahan, E.K. ; Macleod, D. ; Weiss, H.A. ; Burton, M.J. ;
Lancet Glob Health
Defining Seropositivity Thresholds for Use in Trachoma Elimination Studies.
Migchelsen, S.J. ; Martin, D.L. ; Southisombath, K. ; Turyaguma, P. ; Heggen, A. ; Rubangakene, P.P. ; Joof, H. ; Makalo, P. ; Cooley, G. ; Gwyn, S. ; Solomon, A.W. ; Holland, M.J. ; Courtright, P. ; Willis, R. ; Alexander, N.D. ; Mabey, D.C. ; Roberts, C.H. ;
PLoS Negl Trop Dis
Serology reflects a decline in the prevalence of trachoma in two regions of The Gambia.
Migchelsen, S.J. ; Sepúlveda, N. ; Martin, D.L. ; Cooley, G. ; Gwyn, S. ; Pickering, H. ; Joof, H. ; Makalo, P. ; Bailey, R. ; Burr, S.E. ; Mabey, D.C.W. ; Solomon, A.W. ; Roberts, C.H. ;
Sci Rep
Active Trachoma Cases in the Solomon Islands Have Varied Polymicrobial Community Structures but Do Not Associate with Individual Non-Chlamydial Pathogens of the Eye.
Butcher, R.M.R. ; Sokana, O. ; Jack, K. ; Kalae, E. ; Sui, L. ; Russell, C. ; Houghton, J. ; Palmer, C. ; Holland, M.J. ; Le Mesurier, R.T. ; Solomon, A.W. ; Mabey, D.C.W. ; Roberts, C.H. ;
Front Med (Lausanne)
Low Prevalence of Conjunctival Infection with Chlamydia trachomatis in a Treatment-Naïve Trachoma-Endemic Region of the Solomon Islands.
Butcher, R.M. ; Sokana, O. ; Jack, K. ; Macleod, C.K. ; Marks, M.E. ; Kalae, E. ; Sui, L. ; Russell, C. ; Tutill, H.J. ; Williams, R.J. ; Breuer, J. ; Willis, R. ; Le Mesurier, R.T. ; Mabey, D.C. ; Solomon, A.W. ; Roberts, C.H. ;
PLoS Negl Trop Dis
Conjunctival fibrosis and the innate barriers to Chlamydia trachomatis intracellular infection: a genome wide association study.
Roberts, C.H. ; Franklin, C.S. ; Makalo, P. ; Joof, H. ; Sarr, I. ; Mahdi, O.S. ; Sillah, A. ; Bah, M. ; Payne, F. ; Jeffreys, A.E. ; Bottomley, W. ; Natividad, A. ; Molina-Gonzalez, S. ; Burr, S.E. ; Preston, M. ; Kwiatkowski, D. ; Rockett, K.A. ; Clark, T.G. ; Burton, M.J. ; Mabey, D.C. ; Bailey, R. ; Barroso, I. ; Holland, M.J. ;
Sci Rep
See all Dr Chrissy Roberts's Publications