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Dr Gyaviira Nkurunungi

Associate Professor

United Kingdom

Gyaviira Nkurunungi is an immunologist. He holds a PhD in immuno-epidemiology (2016–2019) and an MSc in immunology (2013–2014), both from the London School of Hygiene & Tropical Medicine, funded by the African Partnership for Chronic Disease Research and the Commonwealth Scholarships Commission, respectively. Gyaviira was Africa’s first member of the EMBO Global Investigator Network and currently leads the Immunomodulation and Vaccines Group at the MRC/UVRI and LSHTM Uganda Research Unit.

Affiliations

MRC/UVRI and LSHTM Uganda Research Unit

Teaching

Gyaviira is a UK Higher Education Academy fellow. He teaches on LSHTM’s MSc in Immunology, and tutors on LSHTM’s MSc in Infectious Diseases (Distance Learning) and Makerere's Master of Medicine. He currently supervises three PhD students, and frequently supervises MSc research projects.

Research

Gyaviira’s research focuses on the immunomodulatory effects of environmental exposures on both communicable and non-communicable diseases, and on vaccine immunogenicity and effectiveness. His PhD investigated immunological mechanisms underlying helminth–allergy associations in rural and urban Uganda, with an emphasis on antibody responses. Earlier in his career, he contributed to research on childhood tuberculosis infection, including studies on the utility of interferon-gamma release assays in Ugandan children. He previously led the immunology team on an MRC UKRI-funded programme of Ugandan vaccine trials exploring population differences in vaccine-specific responses. His work integrates cutting-edge wet-lab techniques with advanced computational approaches to identify biological predictors of vaccine response. He is a member of the HypoVax Global Knowledge Hub on Tackling Vaccine Hyporesponsiveness (https://hypovax.org), and serves as immunology lead for the NIH-funded Uganda Schistosomiasis Multidisciplinary Research Centre, which seeks to uncover the biological drivers of severe schistosomal morbidity.

Research Area
Helminths
Hygiene
Immunisation
Parasites
Vaccines
Epidemiology
Immunoepidemiology
Immunology
Parasitology
Vaccinology
Disease and Health Conditions
Allergy
Asthma
Neglected Tropical Diseases (NTDs)
Schistosomiasis
Infectious diseases
Country
Uganda
United Kingdom
Region
Sub-Saharan Africa (developing only)

Selected Publications

Rural-urban differences in oral typhoid vaccine responses in Uganda: contribution of Schistosoma mansoni.
Walusimbi, B; Natukunda, A; Amongin, R; Heyraud, V; Baine, C; Nassuuna, J; WEBB, EL; ELLIOTT, AM; NKURUNUNGI, G;
2026
NPJ vaccines
Life Course Malaria Exposure and SARS-CoV-2 Seroepidemiology in Ugandan Adolescents: A Longitudinal Study Nested in a Birth Cohort.
ZIRIMENYA, L; Nayebare, D; Baine, C; Nassuuna, J; Namutebi, M; Zziwa, C; Nsubuga, D; Kiwudhu, F; Akello, F; Tumusiime, J; Oduru, G; Kabami, G; Akurut, H; Nakyesige, R; Natukunda, A; WAJJA, A; Lubyayi, L; Kimuda, S; NKURUNUNGI, G; Serwanga, J; Doores, KJ; WEBB, EL; ELLIOTT, AM;
2026
Tropical medicine & international health : TM & IH
Data supporting "Rural-urban differences in oral typhoid vaccine responses in Uganda: role of Schistosoma mansoni"
NKURUNUNGI, G; Walusimbi, B;
2026
London School of Hygiene & Tropical Medicine
Data for: "Effect of malaria intermittent preventive treatment on SARS-CoV-2 seroprevalence and response to COVID-19 vaccination: longitudinal study nested within a randomised controlled trial"
ZIRIMENYA, L; Nassuuna, J; Nayebare, D; Baine, C; Namutebi, M; Zziwa, C; Nsubuga, D; Oduru, G; Akello-Ateng, F; Ninsiima, C; Mutebe, A; Wajja, A; Kimuda, S; Natukunda, A; NKURUNUNGI, G; Serwanga, J; ELLIOTT, A; WEBB, E;
2026
London School of Hygiene & Tropical Medicine
Data for "Life course malaria exposure and SARS-CoV-2 Sero-epidemiology in Ugandan adolescents: a longitudinal study nested in a birth cohort"
Zirimenya, L; NKURUNUNGI, G; Natukunda, A; Nassuna, J; Nakyesige, R; Nayebare, D; Baine, C; ELLIOTT, AM; WEBB, E;
2026
London School of Hygiene & Tropical Medicine
Tackling vaccine hyporesponsiveness through global collaboration, diverse population studies, and data integration.
Amoah, AS; Agnandji, ST; Bengtson, M; Downs, JA; Esen, M; Giddaluru, J; Jochems, SP; Kaisar, MM M; Makinde, J; Manurung, MD; Mbow, M; Moncunill, G; Murugan, R; Mutai, J; Nakaya, HI; NKURUNUNGI, G; Palmblad, M; Pyuza, JJ; Stam, KA; De Steenhuijsen Piters, WA A; Walusimbi, B; Yazdanbakhsh, M; Participants of the Lorentz Center Workshop titled,;
2025
The Lancet. Microbe
Metabolic dysfunction impairs Mycobacterium tuberculosis-specific cytokine and chemokine responses in latent tuberculosis and type 2 diabetes mellitus.
Ssekamatte, P; SITENDA, D; Nabatanzi, R; NKURUNUNGI, G; Nakibuule, M; Kibirige, D; Kyazze, AP; Kateete, DP; Bagaya, BS; Sande, OJ; Van Crevel, R; COSE, S; Biraro, IA;
2025
Scientific reports
Design of a multi-epitope vaccine against drug-resistant mycobacterium tuberculosis and mycobacterium bovis using reverse vaccinology.
Akurut, E; Gavamukulya, Y; Mulindwa, J; Isiagi, M; Galiwango, R; Bbuye, M; Lujumba, I; Kiberu, D; Nabisubi, P; Kebirungi, G; Kambugu, A; Castelnuovo, B; NKURUNUNGI, G; Jjingo, D; Oketch, B; Kateete, DP; Mboowa, G;
2025
Scientific reports
Temporal trends of SARS-CoV-2 exposure in adolescents: a longitudinal pilot study nested in a Uganda birth cohort.
ZIRIMENYA, L; Nassuuna, J; Namutebi, M; Zziwa, C; Serubanja, J; Nsubuga, D; Kiwudhu, F; Akello, F; Tumusiime, J; Ninsiima, C; Oduru, G; Kabami, G; Akurut, H; Nakyesige, R; Kimuda, S; WAJJA, A; NKURUNUNGI, G; SERWANGA, J; Doores, KJ; WEBB, EL; ELLIOTT, AM;
2025
NIHR open research
Exploring interrelationships between structural, social, and biological determinants of vaccine impact in Kenya and Uganda: VAnguard community mixed methods study protocol
Etyang, T; ZIRIMENYA, L; Njue, M; NALWANGA, R; Zalwango, F; Abuga, KM; Karanja, HK; Mumba, N; Owino, EA; Eoju, W; Kukundakwe, C; Nsubuga, D; Baine, C; Walusimbi, B; NKURUNUNGI, G; Natukunda, A; Chibita, M; Mafigiri, DK; Kamuya, D; Atkinson, S; Chi, P; WEBB, EL; Trotter, CL; Kaleebu, P; ELLIOTT, AM;
2025
NIHR open research
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