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Eunice KIAMBA

Post-Doctoral Research Fellow

MRC Unit the Gambia
Atlantic Boulevard Road
Fajara, Banjul
Gambia

I am an early career immunologist and postdoctoral fellow at MRC Unit The Gambia at LSHTM and a tutor at LSHTM. I hold a PhD (immunology) from the London School of Hygiene and Tropical Medicine, an MSc (molecular biology and biotechnology) from Jomo Kenyatta University of Agriculture and Technology, and a Bachelor of Science degree (Biochemistry) from Pwani University.

My research focuses on vaccine immunology, with expertise in B cell and T follicular helper cell responses to understand mechanisms of protective immunity. My PhD work centered on immune responses to the Gardasil 9 human papillomavirus vaccine.

I am currently leading B cell profiling and monoclonal antibody research in MRC Unit The Gambia as part of the Genotype to Phenotype Global consortium evaluating immunity to SARS-CoV-2 across three continents (Africa , Europe and Asia).

I aim to continue expanding B cell and monoclonal antibody research portfolio in the Unit to include other diseases of global health relevance.

Centres

Vaccine Centre

Teaching

I am a co-tutor in MSc distance learning module: Immunology of infection and vaccines at the Faculty of Infection and Tropical Disease where I co-teach on the immunology of HPV vaccines alongside Prof. Helen Kelly and contribute to student assessment by marking examination scripts and providing constructive feedback. I plan to take up MSc and PhD supervision roles atthe school strating the next academic year.

In addition, I have contributed to supporting students in different ways both in MRC Unit The Gambia where I have been based since 2019 and elsewhere. I currently support two PhD students in our research group and mentor one master’s and five undergraduate students in Kenyan and Gambian universities. I supported two undergraduate student projects within my PhD research: a visiting student from the Universiy of Liverpool and MRC staff student who later received an Erasmus Mundus Joint Master’s Scholarship.

 I often support the training of laboratory staff and students on immunological techniques including ELISpots, FluoroSpots, flow cytometry immunophenotyping and single-cell sorting, HLA typing. I offered a two-week hands-on flow cytometry training to two visiting students: a master’s student from MRC Unit Uganda, and a PhD student from the University Cheikh Anta Diop (UCAD). Building on this collaboration, we recently hosted 12 immunology students from UCAD who undertook a hands-on flow cytometry training at MRC Unit The Gambia.

As a part-time tutor and research assistant at Pwani University in 2018, I supported several undergraduate and master’s students in their research projects, most of whom have secured scholarships to advance their careers. I was also actively involved in departmental student mentorship programs. For example, in October–November 2018, I co-organised a nine-week course on “Good Research Practices,” culminating in a student symposium with oral and poster presentations and awards, held at Kemri–Wellcome Trust Research Programme, Kenya.

Research

My research focuses on understanding immune responses to vaccination, with a particular emphasis on B cell immunity and the mechanisms that drive effective and durable protection. I am especially interested in dissecting the interplay between innate and adaptive immune responses following vaccination, using systems immunology approaches such as transcriptomics.

During my doctoral and postdoctoral work, I have investigated immune responses to the Gardasil 9 human papillomavirus (HPV) vaccine, characterizing B cell and T follicular helper cell dynamics across different dosing regimens and age groups.

My current work extends this by exploring early innate immune activation pathways using RNA sequencing to identify molecular signatures associated with vaccine-induced immunity.

I aim to build expertise in advanced B cell profiling and monoclonal antibody discovery, with the goal of developing locally driven capacity in sub-Saharan Africa. My long-term vision is to apply these approaches to study both infectious and non-communicable diseases of regional relevance, contributing to the development of next-generation vaccines and immunotherapies.

Research Area
Immunology
Molecular biology
Serology, vaccines
Disease and Health Conditions
Human papillomavirus (HPV)
COVID-19
Country
Gambia
Region
Sub-Saharan Africa (all income levels)

Selected Publications

Plasmablast, memory B cell and T follicular helper cell responses after human papillomavirus vaccination: effect of dose number and age.
KIAMBA, EW; Ajiboye, DO; Bashorun, AO; Jallow, MN; Drammeh, L; Bah, S; Jobarteh, T; Kanu, F; Jawla, O; Lamin, J; SEGONDS-PICHON, A; HOLLAND, MJ; GOODIER, MR; ROETYNCK, S; CLARKE, E;
2026
NPJ vaccines
Plasmablast, memory B cell and T follicular helper cell responses after human papillomavirus vaccination: effect of dose number and age
KIAMBA, EW; Ajiboye, DO; Bashorun, AO; Jallow, MN; Drammeh, L; Bah, S; Jobarteh, T; Kanu, F; Jawla, O; Lamin, J; Segonds-Pichon, A; Holland, MJ; Goodier, MR; Roetynck, S; Clarke, E;
2025
Springer Science and Business Media LLC
Immune responses to human papillomavirus infection and vaccination.
KIAMBA, EW; GOODIER, MR; CLARKE, E;
2025
Frontiers in immunology
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