Dr Palwasha Khan
Clinical Associate Professor
London School of Hygiene & Tropical Medicine
United Kingdom
I undertook my specialist clinical training in Sexual Health and HIV medicine in London and currently hold an honorary consultant contract in HIV medicine in Cardiff. During my clinical training, I was fortunate to be awarded an MRC studentship to study the MSc Epidemiology at LSHTM and went on to undertake a Clinical PhD based overseas, funded by the Wellcome Trust on investigating M. tuberculosis transmission in rural Malawi using infection status (inferred from tuberculin skin test positivity) in young children as sentinels of recent transmission.
My clinical training has provided me with biological and clinical insights into a wide variety of infectious diseases and my MSc and PhD training in infectious disease epidemiology has provided me with an in-depth understanding of population-level transmission dynamics and host-pathogen interactions within society. I have subsequently developed considerable expertise in the field of M. tuberculosis transmission as a field epidemiologist. With my specialisation in Sexual Health and HIV medicine and current clinical practice and research training, I have a deep appreciation of the importance of context and how that impacts the individual and population-level outcomes of infectious diseases.
Affiliations
Centres
Teaching
I am one of the module organisers for the in-house Epidemiology of Infectious Diseases and have taught on a wide variety of courses in the in-house and distance learning MSc Epidemiology, MSc Infectious Diseases, MSc Clinical Trials and East Africa DTM&H.
Research
My research focus is on furthering our understanding of M.tuberculosis transmission in different epidemiological contexts and characterising the role of socio-biological mechanisms that are driving disparities in exposure and susceptibility to M. tuberculosis which leads to the differential distribution of tuberculosis observed in populations. I also work with the endTB consortium (https://endtb.org/) to improve the programmatic management of drug-resistant tuberculosis in resource-limited setting through generating a robust evidence base to guide management. I am passionate about using the best available most up-to-date statistical methods to answer the research question
I would like to gain further expertise in the use of advanced formal causal inference methods as part of my research. Novel statistical methods are continuously being developed in the quantitative sciences (ecology, social science, econometrics, cognitive sciences etc.) which allow us to potentially use and combine available multi-level data in models to better describe and understand drivers of M.tuberculosis transmission within societies. These models can then be used to inform the design of new interventions and/or bespoke combination of interventions for a given setting. Targeting TB care and prevention strategies specific to the local epidemiological and societal context are much more likely to be effective than the ‘one size fits all’ approach that has been adopted to date.