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Dr Harparkash Kaur

BSc PhD CSci CChem FRSC

Assistant Professor
Pharmacology

Room
Room 493

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
+44(0)20 7299 4629 (office)

Fax.
0207 299 4720

 Dr Harparkash Kaur gained both her BSc with honours and PhD in chemistry from the Chelsea College (now Kings College), University of London.

PhD thesis: Free Radical Chemistry: Pericyclic Rearrangements and some new spin traps. 

Elected chartered chemist, fellow of the Royal Society of Chemistry in 1999 (CChem FRSC) and designated a chartered scientist (CSci) in 2005.

Harparkash joined LSHTM in 2001 as staff on the Gates Malaria Partnership and is a founder member of the artemisinin combination therapy consortium. She is the director of the LSHTM Bioanalytical facility and the lead investigator of the drug quality project(www.actconsortium.org/drugquality).

Affiliations

Department of Disease Control
Department of Infection Biology
Faculty of Infectious and Tropical Diseases
Department of Clinical Research

Centres

Malaria Centre
Antimicrobial Resistance Centre

Teaching

  • Chair of the CID exam board
  • Academic organiser of the Masters Module "Control and Epidemiology of Malaria".
  • Supervision of MSc projects and practical teaching of chromatographic techniques on Antimicrobial Chemotherapy Study Module.
  • Teaching on both of the above mentioned Study Modules.
  • Supervisor to PhD students.

Research

Harparkash set up the bio analytical laboratory at LSHTM. As an analyst she devised high performance liquid chromatography (HPLC) based methods applicable to varying fields of research such as determining the levels of free radicals in disease state and levels of endogenous antioxidants. Her present research has involved developing / validating HPLC and simple chemical methods to test the quality as well as levels of drugs in patient samples and measuring the levels of insecticids on treated nets and indoor residual spraying that are used as the major mode of intervention in the fight against malaria. The field friendly methods that she has devised for the detection of artemisnin derivatives and for the detection of insecticides have separate granted patents held by the LSHTM. The focus of her work is to determine the quality of drugs, levels of antimalarial drugs on filter paper adsorbed blood samples and amounts of insecticides on bed nets from a number of trials ongoing/planned in Sub-Saharan Africa. Her recent work has expanded to determinining the quality of antibiotics, antihypertensive and antiretroviral medicines purchased in various states within Ghana and Nigeria.

Research Area
Drug resistance
Surveillance
Disease control
Global Health
Medicines
Methodology
Pharmacokinetics
Qualitative methods
Vector control
Discipline
Pharmacology
Disease and Health Conditions
Infectious disease
Malaria
Neglected Tropical Diseases (NTDs)
Country
Afghanistan
Ghana
Equatorial Guinea
Cambodia
Nigeria
Rwanda
Tanzania
Region
South Asia
Sub-Saharan Africa (developing only)
Sub-Saharan Africa (all income levels)

Selected Publications

Equivalence in Active Pharmaceutical Ingredient of Generic Antihypertensive Medicines Available in Nigeria (EQUIMEDS): A Case for Further Surveillance.
Redfern J; Kaur H; Adedoyin RA; Ofori S; Anchala R; Vamadevan AS; De Andrade L; Zelaya J; Balabanova D; Sani MU
2019
Global heart
MS06.5 Equivalence In Active Pharmaceutical Ingredient of Generic Antihypertensive Medicines Available In Three Nigerian States (EQUIMEDS): A Case For Further Surveillance
Redfern J; Adedoyin RA; Ofori S; Anchala R; Vamadevan AS; De Andrade L; Zelaya J; Balabanova D; Sani MU
2018
Global Heart
Para-cresol production by Clostridium difficile affects microbial diversity and membrane integrity of Gram-negative bacteria.
Passmore IJ; Letertre MPM; Preston MD; Bianconi I; Harrison MA; Nasher F; Kaur H; Hong HA; Baines SD; Cutting SM
2018
PLoS pathogens
A New Handheld Device for the Detection of Falsified Medicines: Demonstration on Falsified Artemisinin-Based Therapies from the Field.
Wilson BK; Kaur H; Allan EL; Lozama A; Bell D
2017
The American journal of tropical medicine and hygiene
Prevalence of substandard and falsified artemisinin-based combination antimalarial medicines on Bioko Island, Equatorial Guinea.
Kaur H; Allan EL; Mamadu I; Hall Z; Green MD; Swamidos I; Dwivedi P; Culzoni MJ; Fernandez FM; Garcia G
2017
BMJ global health
Pfk13-independent treatment failure in four imported cases of Plasmodium falciparum malaria given artemether-lumefantrine in the UK.
Sutherland CJ; Lansdell P; Sanders M; Muwanguzi J; van Schalkwyk DA; Kaur H; Nolder D; Tucker J; Bennett HM; Otto TD
2017
Antimicrobial agents and chemotherapy
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