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Dr Max Eyre

Research Fellow

United Kingdom

I joined the Environmental Health Group as a Research Fellow in March 2023 to undertake a three-year RGHI fellowship.

Prior to joining LSHTM I completed my PhD at the Centre for Health Informatics, Computing & Statistics (CHICAS) at Lancaster University, in which I developed a geostatistical framework for modelling zoonotic spillover for leptospirosis. After that I worked on a large schistosomiasis study between the Big Data Institute, University of Oxford and Uganda, and then returned to CHICAS to apply geostatistical methods to map STH in Kenya to inform MDA policy. I hold a Bachelors and Masters of Engineering from Cambridge University and a Master's degree from LSHTM.

Affiliations

Department of Disease Control
Faculty of Infectious and Tropical Diseases

Teaching

I teach on the 'Introduction to Disease Agents and their Control' (IDAC, 3125) on the Control of Infectious Diseases MSc and the Professional Diploma in Tropical Medicine & Hygiene (DTM&H). I am a distance learning tutor for 'IDM104. Control of Infectious Diseases' and regularly supervise MSc research projects and PhD students - any interested students please feel free to contact me.

Research

My research primarily focusses on studying transmission mechanisms of neglected tropical diseases, with a focus on climate-sensitive pathogens, using spatial statistical models and community-based studies.

In this work I apply eco-epidemiological approaches to delineate the mechanisms and complex interactions between animal reservoirs, the environment, climate and human behaviour that drive transmission of these diseases. In this work I use eco-epidemiological study designs and spatiotemporal geostatistical modelling frameworks to jointly collect and analyse data at the human-environment-animal interface.

I am currently undertaking a three-year fellowship to explore the link between environmental hygiene, flooding and health for three climate-sensitive environmental and zoonotic diseases (EZDs) in marginalised urban communities in Salvador, Brazil using a One Health approach. The project aims to address a critical evidence gap on the impact of environmental hygiene interventions (simplified sewerage with community participation and health education) on EZD transmission. The three-year longitudinal study has an eco-epidemiological design consisting of i) a prospective community cohort to serologically identify human infection, ii) environmental sampling of soil and water to measure environmental pathogen load, and iii) animal surveys (rats and domestic animals) to explore zoonotic spillover risk. This study is a collaboration with the Federal University of Bahia and Fiocruz in Salvador, Brazil.
Research Area
GIS/Spatial analysis
Statistical methods
Epidemiology
Disease control
Environmental hygiene
Environmental health
Climate change
Complex interventions
Sanitation
Hygiene
Modelling
Protozoa
Bacteria
Social and structural determinants of health
Disease and Health Conditions
Leptospirosis
Toxoplasmosis
Dengue
Soil transmitted helminths
Neglected Tropical Diseases (NTDs)
Zoonoses
Vector borne diseases
Infectious diseases
Country
Brazil
United Kingdom
Region
Latin America & Caribbean (all income levels)

Selected Publications

Linking rattiness, geography and environmental degradation to spillover <i>Leptospira</i> infections in marginalised urban settings: An eco-epidemiological community-based cohort study in Brazil.
EYRE, MT; Souza, FN; Carvalho-Pereira, TS A; Nery, N; De Oliveira, D; Cruz, JS; Sacramento, GA; Khalil, H; Wunder, EA; Hacker, KP; Hagan, JE; Childs, JE; Reis, MG; Begon, M; Diggle, PJ; Ko, AI; Giorgi, E; Costa, F;
2022
eLife
SARS-CoV-2 antibodies and breakthrough infections in the Virus Watch cohort.
Aldridge, RW; Yavlinsky, A; Nguyen, V; EYRE, MT; Shrotri, M; Navaratnam, AM D; Beale, S; Braithwaite, I; Byrne, T; Kovar, J; FRAGASZY, E; Fong, WL E; Geismar, C; Patel, P; Rodger, A; Johnson, AM; Hayward, A;
2022
Nature Communications
Effect of Sewerage on the Contamination of Soil with Pathogenic Leptospira in Urban Slums.
Casanovas-Massana, A; Neves Souza, F; Curry, M; De Oliveira, D; De Oliveira, AS; EYRE, MT; Santiago, D; Aguiar Santos, M; Serra, RM R; Lopes, E; Xavier, BI; Diggle, PJ; Wunder, EA; Reis, MG; Ko, AI; Costa, F;
2021
Environmental science & technology
Poverty, sanitation, and Leptospira transmission pathways in residents from four Brazilian slums.
Khalil, H; Santana, R; De Oliveira, D; Palma, F; Lustosa, R; EYRE, MT; Carvalho-Pereira, T; Reis, MG; Ko, AI; Diggle, PJ; Alzate Lopez, Y; Begon, M; Costa, F;
2021
PLoS neglected tropical diseases
Impact of baseline cases of cough and fever on UK COVID-19 diagnostic testing rates: estimates from the Bug Watch community cohort study.
EYRE, MT; Burns, R; Kirkby, V; Smith, C; Denaxas, S; Nguyen, V; Hayward, A; Shallcross, L; FRAGASZY, E; Aldridge, RW;
2021
Wellcome open research
COVID-19 among people experiencing homelessness in England: a modelling study.
Lewer, D; Braithwaite, I; Bullock, M; EYRE, MT; White, PJ; Aldridge, RW; Story, A; Hayward, AC;
2020
The Lancet. Respiratory medicine
A multivariate geostatistical framework for combining multiple indices of abundance for disease vectors and reservoirs: a case study of <i>rattiness</i> in a low-income urban Brazilian community.
EYRE, MT; Carvalho-Pereira, TS A; Souza, FN; Khalil, H; Hacker, KP; Serrano, S; Taylor, JP; Reis, MG; Ko, AI; Begon, M; Diggle, PJ; Costa, F; Giorgi, E;
2020
Journal of the Royal Society, Interface
Piloting an integrated approach for estimation of environmental risk of Schistosoma haematobium infections in pre-school-aged children and their mothers at Barombi Kotto, Cameroon.
EYRE, MT; Stanton, MC; Macklin, G; Bartoníček, Z; O'Halloran, L; Eloundou Ombede, DR; Chuinteu, GD; Stewart, M; LaCourse, EJ; Tchuem Tchuenté, LA; Stothard, JR;
2020
Acta tropica
Gender differences in the perception of leptospirosis severity, behaviours, and Leptospira exposure risk in urban Brazil: a cross-sectional study.
Delight, EA; Santiago, DC D C; Palma, FA G; De Oliveira, D; Souza, FN; Santana, JO; Hidano, A; Alzate López, YA; Reis, MG G; Ko, AI; Marphatia, AA; Cremonense, C; Costa, F; EYRE, MT;
2024
medRxiv
A Comparison of Markov and Mechanistic Models for Soil-Transmitted Helminth Prevalence Projections in the Context of Survey Design.
EYRE, MT; Bulstra, CA; Johnson, O; De Vlas, SJ; Diggle, PJ; Fronterrè, C; Coffeng, LE;
2024
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
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