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Dr Ruth Costello

Research Fellow

United Kingdom

I joined the EHR group in 2022 as a research fellow to work on OpenSAFELY projects, investigating healthcare disruption related to the pandemic and repurposing of drugs to treat COVID-19. I previously worked at the University of Manchester where I mainly used CPRD data in studies in the area of rheumatic diseases. While working in Manchester I completed my PhD by publication, this included 7 studies with the theme of using digital data to investigate the management of rheumatoid arthritis.

Affiliations

Department of Non-communicable Disease Epidemiology
Faculty of Epidemiology and Population Health

Selected Publications

Clinical coding of long COVID in primary care 2020–2023 in a cohort of 19 million adults: an OpenSAFELY analysis
Henderson, AD; Butler-Cole, BF C; Tazare, J; TOMLINSON, LA; MARKS, M; JIT, M; BRIGGS, A; Lin, L-Y; Carlile, O; Bates, C; Parry, J; Bacon, SC J; Dillingham, I; Dennison, WA; Costello, RE; Wei, Y; Walker, AJ; Hulme, W; GOLDACRE, B; Mehrkar, A; MacKenna, B; Walker, A; Green, A; Mehrkar, A; Schaffer, A; ... EGGO, RM.
2024
eClinicalMedicine
Impacts of the COVID-19 pandemic on deprivation-level differences in cardiovascular hospitalisations: A comparison of England and Denmark using the OpenSAFELY platform and National Registry Data
COSTELLO, R; Henderson, A; Tazare, J; Pedersen, L; Sorensen, HT; Vandenbroucke, J; MANSFIELD, K; Mahalingasivam, V; Zheng, B; Carreira, H; Bidulka, P; Piehlmaier, D; Wong, AY S; Warren-Gash, C; Hayes, J; Quint, J; Katikireddi, SV; MacKenna, B; Mehrkar, A; Bacon, S; GOLDACRE, B; Tomlinson, L; LANGAN, S; Mathur, R; The LH&W NCS (or CONVALESCENCE) Collaborative and ,;
2024
medRxiv
Impact of long COVID on health-related quality-of-life: an OpenSAFELY population cohort study using patient-reported outcome measures (OpenPROMPT).
CARLILE, O; BRIGGS, A; Henderson, AD; Butler-Cole, BF C; Tazare, J; TOMLINSON, LA; MARKS, M; JIT, M; Lin, L-Y; Bates, C; Parry, J; Bacon, SC J; Dillingham, I; Dennison, WA; COSTELLO, RE; Walker, AJ; Hulme, W; GOLDACRE, B; Mehrkar, A; MacKenna, B; OpenSAFELY Collaborative,; HERRETT, E; EGGO, RM;
2024
The Lancet Regional Health - Europe
OpenSAFELY: The impact of COVID-19 on azathioprine, leflunomide and methotrexate monitoring, and factors associated with change in monitoring rate.
Brown, AD; Fisher, L; Curtis, HJ; Wiedemann, M; Hulme, WJ; Speed, V; Hopcroft, LE M; Cunningham, C; COSTELLO, RE; Galloway, JB; Russell, MD; Bechman, K; Kurt, Z; Croker, R; Wood, C; Walker, AJ; Schaffer, AL; Bacon, SC J; Mehrkar, A; Hickman, G; Bates, C; Cockburn, J; Parry, J; Hester, F; Harper, S; ... MacKenna, B.
2024
British Journal of Clinical Pharmacology
Ursodeoxycholic acid and severe COVID-19 outcomes in people with liver disease: a cohort study using the OpenSAFELY platform
COSTELLO, R; Jean Waller, KM; Smith, R; Mells, G; Wong, AY S; Schultze, A; Mahalingasivam, V; Herrett, E; Zheng, B; Lin, L-Y; Mehrkar, A; Bacon, SC J; GOLDACRE, B; Tomlinson, L; Tazare, J; RENTSCH, C; The OpenSAFELY collaborative and the LH&W NCS (or ,;
2023
medRxiv
The impact of Long COVID on Health-Related Quality-of-Life using OpenPROMPT
CARLILE, O; BRIGGS, A; Henderson, A; Butler-Cole, BF C; TAZARE, J; TOMLINSON, L; MARKS, M; JIT, M; LIN, L-Y; Bates, C; Parry, J; Bacon, SC J; Dillingham, I; Dennison, W; COSTELLO, R; Walker, A; Hulme, W; GOLDACRE, B; Mehrkar, A; MacKenna, B; HERRETT, E; EGGO, R; The OpenSAFELY Collaborative,;
2023
medRxiv
Comparative effectiveness of nirmatrelvir/ritonavir versus sotrovimab and molnupiravir for preventing severe COVID-19 outcomes in non-hospitalised high-risk patients during Omicron waves: observational cohort study using the OpenSAFELY platform.
ZHENG, B; Tazare, J; Nab, L; Green, AC; Curtis, HJ; MAHALINGASIVAM, V; HERRETT, EL; COSTELLO, RE; EGGO, RM; Speed, V; Bacon, SC; Bates, C; Parry, J; Cockburn, J; Hester, F; Harper, S; Schaffer, AL; Hulme, WJ; Mehrkar, A; EVANS, SJ; MacKenna, B; GOLDACRE, B; DOUGLAS, IJ; TOMLINSON, LA; OpenSAFELY Collaborative,;
2023
The Lancet Regional Health - Europe
Living alone and mental health: parallel analyses in UK longitudinal population surveys and electronic health records prior to and during the COVID-19 pandemic.
McElroy, E; HERRETT, E; Patel, K; Piehlmaier, DM; Gessa, GD; Huggins, C; Green, MJ; Kwong, AS F; Thompson, EJ; Zhu, J; MANSFIELD, KE; Silverwood, RJ; Mansfield, R; Maddock, J; Mathur, R; COSTELLO, RE; Matthews, A; TAZARE, J; HENDERSON, A; WING, K; Bridges, L; Bacon, S; Mehrkar, A; OpenSAFELY Collaborative,; Shaw, RJ; ... Longitudinal Health and Wellbeing Collaborative,
2023
BMJ mental health
Ethnic differences in the indirect effects of the COVID-19 pandemic on clinical monitoring and hospitalisations for non-COVID conditions in England: a population-based, observational cohort study using the OpenSAFELY platform.
COSTELLO, RE; Tazare, J; Piehlmaier, D; HERRETT, E; Parker, EP K; ZHENG, B; Mansfield, KE; HENDERSON, AD; CARREIRA, H; BIDULKA, P; WONG, AY S; WARREN-GASH, C; Hayes, JF; Quint, JK; MacKenna, B; Mehrkar, A; EGGO, RM; Katikireddi, SV; TOMLINSON, L; LANGAN, SM; Mathur, R; LH&W NCS (or CONVALESCENCE) Collaborative,; OpenSAFELY collaborative,;
2023
EClinicalMedicine
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