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Dr Ruth Costello

Research Fellow

United Kingdom

I am a research fellow and I use electronic health record data in epidemiology and pharmacoepidemiology studies. Recent work has investigated inequalities in healthcare disruption related to the pandemic and repurposing of drugs to treat COVID-19. I previously worked at the University of Manchester where I used CPRD data in studies in the field of rheumatology. While working in Manchester I completed my PhD by publication, this included 7 studies with the theme of using digital data to investigate the management of rheumatoid arthritis.

Affiliations

Department of Non-communicable Disease Epidemiology
Faculty of Epidemiology and Population Health

Teaching

I am co-course organise for block 2 - "Introduction to Pharmacovigilance" in the Pharmacoepidemiology and pharmacovigilance short course. I also teach on the extended epidemiology module. 

Selected Publications

Ursodeoxycholic acid and severe COVID-19 outcomes in people with liver disease: a cohort study using the OpenSAFELY platform
COSTELLO, R; Waller, K; Smith, R; Mells, G; WONG, A; SCHULTZE, A; MAHALINGASIVAM, V; HERRETT, E; Zheng, B; Lin, L-Y; Mehrkar, A; Bacon, S; Goldacre, B; MacKenna, B; TAZARE, J; Rentsch, PhD, FISPE, C; TOMLINSON, L;
2024
Communications Medicine
Impacts of the COVID-19 pandemic on deprivation-level differences in cardiovascular hospitalisations: a comparison of England and Denmark using the OpenSAFELY platform and National Registry Data.
COSTELLO, RE; Pedersen, L; Henderson, AD; TAZARE, J; Sorensen, HT; Vandenbroucke, JP; Mansfield, KE; MAHALINGASIVAM, V; Zheng, B; CARREIRA, H; BIDULKA, P; Piehlmaier, DM; WONG, AY S; WARREN-GASH, C; Hayes, JF; Quint, JK; Katikireddi, SV; Mackenna, B; Mehrkar, A; Bacon, S; Goldacre, B; TOMLINSON, LA; LANGAN, SM; Mathur, R; Collaborative, TL W N O C; ... Consortium, TO.
2024
BMJ open
Checklist and guidance on creating codelists for routinely collected health data research.
MATTHEWMAN, J; ANDRESEN, K; SUFFEL, A; Lin, L-Y; SCHULTZE, A; TAZARE, J; BHASKARAN, K; WILLIAMSON, E; COSTELLO, R; Quint, J; STRONGMAN, H;
2024
NIHR open research
Incidence of diabetes after SARS-CoV-2 infection in England and the implications of COVID-19 vaccination: a retrospective cohort study of 16 million people.
Taylor, K; Eastwood, S; Walker, V; Cezard, G; Knight, R; Al Arab, M; Wei, Y; Horne, EM F; Teece, L; FORBES, H; Walker, A; Fisher, L; Massey, J; Hopcroft, LE M; Palmer, T; Cuitun Coronado, J; Ip, S; Davy, S; Dillingham, I; Morton, C; Greaves, F; Macleod, J; GOLDACRE, B; Wood, A; Chaturvedi, N; ... OpenSAFELY collaborative,
2024
The lancet. Diabetes & endocrinology
Clinical coding of long COVID in primary care 2020-2023 in a cohort of 19 million adults: an OpenSAFELY analysis.
Henderson, AD; Butler-Cole, BF; Tazare, J; TOMLINSON, LA; MARKS, M; JIT, M; BRIGGS, A; Lin, L-Y; CARLILE, O; Bates, C; Parry, J; Bacon, SC; Dillingham, I; Dennison, WA; COSTELLO, RE; Wei, Y; Walker, AJ; Hulme, W; GOLDACRE, B; Mehrkar, A; MacKenna, B; OpenSAFELY Collaborative,; HERRETT, E; Eggo, RM;
2024
EClinicalMedicine
Impacts of the COVID-19 pandemic on deprivation-level differences in cardiovascular hospitalisations: A comparison of England and Denmark using the OpenSAFELY platform and National Registry Data
COSTELLO, R; Henderson, A; Tazare, J; Pedersen, L; Sorensen, HT; Vandenbroucke, J; MANSFIELD, K; Mahalingasivam, V; Zheng, B; Carreira, H; Bidulka, P; Piehlmaier, D; Wong, AY S; WARREN-GASH, C; Hayes, J; Quint, J; Katikireddi, SV; MacKenna, B; Mehrkar, A; Bacon, S; GOLDACRE, B; Tomlinson, L; LANGAN, S; Mathur, R; The LH&W NCS (or CONVALESCENCE) Collaborative and ,;
2024
medRxiv
Impact of long COVID on health-related quality-of-life: an OpenSAFELY population cohort study using patient-reported outcome measures (OpenPROMPT).
CARLILE, O; BRIGGS, A; Henderson, AD; Butler-Cole, BF C; Tazare, J; TOMLINSON, LA; MARKS, M; JIT, M; Lin, L-Y; Bates, C; Parry, J; Bacon, SC J; Dillingham, I; Dennison, WA; COSTELLO, RE; Walker, AJ; Hulme, W; GOLDACRE, B; Mehrkar, A; MacKenna, B; OpenSAFELY Collaborative,; HERRETT, E; EGGO, RM;
2024
The Lancet Regional Health - Europe
OpenSAFELY: The impact of COVID-19 on azathioprine, leflunomide and methotrexate monitoring, and factors associated with change in monitoring rate.
Brown, AD; Fisher, L; Curtis, HJ; Wiedemann, M; Hulme, WJ; Speed, V; Hopcroft, LE M; Cunningham, C; COSTELLO, RE; Galloway, JB; Russell, MD; Bechman, K; Kurt, Z; Croker, R; Wood, C; Walker, AJ; Schaffer, AL; Bacon, SC J; Mehrkar, A; Hickman, G; Bates, C; Cockburn, J; Parry, J; Hester, F; Harper, S; ... MacKenna, B.
2024
British Journal of Clinical Pharmacology
opensafely/covid_collateral_imd
COSTELLO, R; Henderson, A;
2024
Github
Ursodeoxycholic acid and severe COVID-19 outcomes in people with liver disease: a cohort study using the OpenSAFELY platform
COSTELLO, R; Waller, K; Smith, R; Mells, G; WONG, A; SCHULTZE, A; MAHALINGASIVAM, V; HERRETT, E; Zheng, B; Lin, L-Y; Mehrkar, A; Bacon, S; Goldacre, B; MacKenna, B; TAZARE, J; Rentsch, PhD, FISPE, C; TOMLINSON, L;
2024
Communications Medicine
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