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Dr Muhammed Afolabi

MBBS MPH PhD FWACP FHEA

Assistant Professor

Room
412

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
020 7929 2301

Muhammed Afolabi obtained a medical degree from the University of Ibadan and a master’s degree in Public Health from Obafemi Awolowo University, both in Nigeria, West Africa. He also underwent specialist medical training leading to the award of a postgraduate fellowship of the West African College of Physicians in Family Medicine. He obtained a PhD from the London School of Hygiene & Tropical Medicine (LSHTM) in 2015.

Muhammed joined LSHTM in 2016 to work on the School's Ebola vaccine project based in Kambia, northern Sierra Leone, where he led the preparations and conduct of the paediatric components of the trials; the findings of which contributed to the approval of the novel two-dose Ebola vaccine regimen (ZABDENO/MVABEA) by the European Medicines Agency.  

Muhammed’s research antecedents at the MRC Unit, The Gambia (MRCG) from 2009-2016 were in the evaluation of HIV and malaria vaccines in adult and paediatric populations.  He led the collaborative trial involving MRCG and Université Cheikh Anta Diop (UCAD), Senegal to evaluate the safety and immunogenicity of malaria vaccines when co-administered with routine childhood immunisations in infants and neonates. This successful South-South collaboration became a reference point for the funder (EDCTP); the results of which contributed to the award of a scholarship fellowship for a master’s degree in Vaccinology at the University of Sienna, Italy for a member of the trial team. 

Muhammed has a track record of developing innovative solutions to address the unmet needs of the populations he works with. For example, to address the perennial challenges faced when communicating essential research information to low-literacy research participants, Muhammed developed and evaluated in a randomised controlled trial a simplified alternative method of delivering consent information using a locally designed multimedia tool which integrated video, animations and audio narrations in local languages. This study formed the basis of his highly regarded PhD, which he passed without requiring any corrections from the Examiners. The multimedia consent tool has changed the way informed consent procedure is conducted at MRCG and deservedly led to the award of prizes including MRCG Director's Award in 2013 and MRC Chief Executive Officer Award in 2014.

Affiliations

Department of Disease Control
Faculty of Infectious and Tropical Diseases

Centres

Malaria Centre
Vaccine Centre

Teaching

Muhammed has successfully completed the prescribed modules of Postgraduate Certificate in Learning and Teaching at the LSHTM and has become a Fellow of the Higher Education Academy (FHEA). He has a wide range of teaching activities, which include:

  • Neglected Tropical Diseases Module 3465 (MSc Control of Infectious Diseases)
  • Control of Infectious Diseases - IDM 104 (MSc Infectious Diseases),
  • Project Management and Research Coordination - CTM 203 (MSc Clinical Trials)
  • Examiner for MSc, PG Diploma and PG Certificate in Clinical Trials
  • Examiner for MSc, PG Diploma and PG Certificate in Infectious Diseases

In response to physical distancing measures occasioned by COVID-19 pandemic, Muhammed was appointed a Digital Learning Design Champion, where he is poised to utilise his pedagogical and digital skill sets to support LSHTM efforts to maintain global leadership in postgraduate education.

Research

Muhammed is currently working on a prestigious UKRI Future Leaders Fellowship, designed to tackle the difficult and novel challenges posed by co-endemicity of malaria and helminths in a high-risk paediatric population by investigating the feasibility and effectiveness of integrating helminth control with seasonal malaria chemoprevention (SMC). This adventurous programme will hopefully lead to the implementation of an increasingly recognised strategy of integrated, non-disease specific approach to controlling tropical anaemia.

Research Area
Clinical care
Clinical trials
Helminths
Primary care
Public health
Systematic reviews
Vaccines
Ethics
Global Health
Immunisation
Medicines
Mixed methods
Mobile technologies
Implementation research
Qualitative methods
Randomised controlled trials
Reproductive health
Discipline
Epidemiology
Medicine
Vaccinology
Disease and Health Conditions
HIV/AIDS
Infectious disease
Malaria
Emerging Infectious Disease
Schistosomiasis
Tropical diseases
Soil-transmitted helminths
Country
The Gambia
Nigeria
Senegal
Sierra Leone
Region
Sub-Saharan Africa (all income levels)
World

Selected Publications

Malaria and helminth co-infections in children living in endemic countries: A systematic review with meta-analysis.
Afolabi MO; Ale BM; Dabira ED; Agbla SC; Bustinduy AL; Ndiaye JLA; Greenwood B
2021
PLoS Neglected Tropical Diseases
Safety and immunogenicity of the two-dose heterologous Ad26.ZEBOV and MVA-BN-Filo Ebola vaccine regimen in children in Sierra Leone: a randomised, double-blind, controlled trial
Afolabi MO; Ishola D; Manno D; Keshinro B; Bockstal V; Rogers B; Owusu-Kyei K; Serry-Bangura A; Swaray I; Lowe B
2021
Lancet Infectious Diseases
Safety and long-term immunogenicity of a two-dose Ad26.ZEBOV, MVA-BN-Filo Ebola vaccine in adults in Sierra Leone: a randomised trial, double-blind, controlled trial
Ishola D; Manno D; Afolabi MO; Keshinro B; Bokstal V; Rogers B; Robinson C; Leyssen M; Greenwood B; Douoguih M
2021
Lancet Infectious Diseases
Clinical presentations and management of COVID-19 infected children seen in a district health facility in Kambia, northern Sierra Leone
Adetola HH; Ishola D; Afolabi MO; Bangura J; Sesay IG; Pearce R; Garrick I; Kamara B; Leigh B; Greenwood B
2020
Pan African Medical Journal
Lessons from the Ebola epidemics and their applications for COVID-19 pandemic response in sub-Saharan Africa.
Afolabi MO; Folayan MO; Munung NS; Yakubu A; Ndow G; Jegede A; Ambe J; Kombe F
2020
DEVELOPING WORLD BIOETHICS
COVID-19 in Nigeria: Implications for Management of Related Co-morbidities, Prevalent Public Health Challenges, and Future Epidemic Preparedness
Ola BA; Nkereuwem E; Oriero E; Okomo U; Afolabi M; Togun T
2020
Proceedings of the Nigerian Academy of Science
Considerations for community engagement when conducting clinical trials during infectious disease emergencies in West Africa.
Folayan MO; Allman D; Haire B; Yakubu A; Afolabi MO; Cooper J
2018
DEVELOPING WORLD BIOETHICS
Research priorities during infectious disease emergencies in West Africa.
Folayan MO; Haire B; Allman D; Yakubu A; Afolabi MO
2018
BMC research notes
Safety and Immunogenicity of Malaria Vectored Vaccines Given with Routine Expanded Program on Immunization Vaccines in Gambian Infants and Neonates: A Randomized Controlled Trial.
Mensah VA; Roetynck S; Kanteh EK; Bowyer G; Ndaw A; Oko F; Bliss CM; Jagne YJ; Cortese R; Nicosia A
2017
Frontiers in immunology
Safety and Immunogenicity of ChAd63 and MVA ME-TRAP in West African Children and Infants.
Afolabi MO; Tiono AB; Adetifa UJ; Yaro JB; Drammeh A; Nébié I; Bliss C; Hodgson SH; Anagnostou NA; Sanou GS
2016
Molecular therapy
A multimedia consent tool for research participants in the Gambia: a randomized controlled trial.
Afolabi MO; McGrath N; D'Alessandro U; Kampmann B; Imoukhuede EB; Ravinetto RM; Alexander N; Larson HJ; Chandramohan D; Bojang K
2015
Bulletin of the World Health Organization
Ebola: a holistic approach is required to achieve effective management and control.
Roca A; Afolabi MO; Saidu Y; Kampmann B
2015
The Journal of allergy and clinical immunology
A phase I randomized clinical trial of candidate human immunodeficiency virus type 1 vaccine MVA.HIVA administered to Gambian infants.
Afolabi MO; Ndure J; Drammeh A; Darboe F; Mehedi S-R; Rowland-Jones SL; Borthwick N; Black A; Ambler G; John-Stewart GC
2013
PLOS ONE
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