Dr Cally Roper BSc PhD

Reader in Malaria Genetics

About Cally Roper

Applied Malaria Genetics


Dr Cally Roper joined the LSHTM in 1996 with a background in Evolution and Population Genetics. Her research interest is in the development and application of novel genetic approaches to questions about malaria treatment and malaria control. In particular she is interested in resistance to antimalarial drugs and identifying the factors which drive its emergence and global dispersal. Current projects include the development of a genetic barcode, mapping resistance mutations in Africa to inform policy on malaria prevention in pregnant women and infants, measuring drug selection applied by the adoption of specific treatment interventions in the field, and assessing the role of human migration in the dispersal of drug resistant malaria.







Module organiser for the distance learning Malaria module.


Barcoding Malaria Parasites: A barcode of organellar genome polymorphisms identifies the geographic origin of Plasmodium falciparum strains.  M.D. Preston, S. Campino, S.A. Assefa, D.F. Echeverry, H. Ocholla, A. Amambua-Ngwa, L. Stewart, D.J. Conway, S. Borrmann, P. Michon, I. Zongo, J-B Ouédraogo, A.A. Djimde, O.K. Doumbo, F. Nosten, A. Pain, T. Bousema, C.J. Drakeley, R.M. Fairhurst, C.J. Sutherland, C. Roper, T.G Clark.   Nature Communications (2014) 5:4052.

Mapping the spread of drug resistance mutations in Africa  http://www.drugresistancemaps.org/   Multiple Origins and Regional Dispersal of Resistant dhps in African Plasmodium falciparum Malaria. R. J. Pearce, H. Pota, M-S B. Evehe, E-H Bâ, G. Mombo-Ngoma, A. L. Malisa, R. Ord, W. Inojosa, A. Matondo, D.A. Diallo, W. Mbacham, I.V.van den Broek, T.D. Swarthout, A. Getachew, S. Dejene, M.P.Grobusch, F. Njie, S. Dunyo, M. Kweku, S. Owusu-Agyei, D. Chandramohan, M. Bonnet, J-P Guthmann, S. Clarke, K.I. Barnes, E. Streat, S.T. Katokele, P. Uusiku, C.O. Agboghoroma, O. Y. Elegba, B. Cissé, I. E. A-Elbasit, H.A. Giha, S.P. Kachur, C. Lynch, J.B. Rwakimari, P. Chanda, M. Hawela, B. Sharp, I. Naidoo, C. Roper.   PLoS Medicine (2009) 6(4):e1000055

Measuring drug pressure in a field trial of intermittent preventive treatment of infants (IPTi). A community-randomised evaluation of the effect of IPTi on antimalarial drug resistance in southern Tanzania. R. J. Pearce , R. Ord, H. Kaur, C. Lupala , J. Schellenberg, K. Shirma, F. Manzi, M. Tanner, P. Alonso, H. Mshinda, C. Roper, D. Schellenberg. The Journal of Infectious Diseases (2013) 207, 849-859. 


Research areas

  • Drug resistance


  • GIS/Spatial analysis
  • Genetics
  • Molecular biology
  • Molecular epidemiology

Disease and Health Conditions

  • Infectious disease
  • Malaria


  • Sub-Saharan Africa (all income levels)
  • World


  • Burkina Faso
  • Cameroon
  • China
  • Colombia
  • Congo, Dem. Rep.
  • Congo, Rep.
  • Ethiopia
  • Gabon
  • Gambia, The
  • Ghana
  • Guinea
  • India
  • Kenya
  • Mozambique
  • Namibia
  • Senegal
  • South Africa
  • South Sudan
  • Sri Lanka
  • Tanzania
  • United Kingdom
  • Zambia

Other interests

  • ACT
  • Africa
  • Antimalarial Drug Resistance
  • Artemisinin Resistance
  • Distance Learning
  • Dried Blood Spots
  • Drug Efficacy
  • East Africa
  • Evidence-informed health policy making
  • Evolution
  • Gambia
  • Genotyping
  • Geography
  • Infectious Diseases
  • Infectious disease policy
  • Insecticide Resistance
  • Intermittent Preventive Treatment
  • Malaria Centre
  • Malaria Prophylaxis
  • Microsatellites
  • Migrant Health
  • Modelling And Mapping Disease Distribution
  • Monitoring And Evaluation
  • Mosquitoes
  • Neglected Tropical Diseases
  • Parasite Clearance
  • Plasmodium malariae
  • Plasmodium ovale
  • Plasmodium vivax
  • Population Based Interventions
  • Population Genetics
  • Population genomics
  • Seasonal Malaria Chemoprevention
  • Sudan
  • Uganda
  • evidence into policy
  • evolutionary ecology
  • getting research into policy
  • malaria vectors
  • migration and health
  • parasites
  • sickle cell disease
  • sub-saharan africa
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