Tel: +44 (0)20 7927 2639 Fax: +44 (0)20 7927 2739
The Department of Pathogen Molecular Biology focuses on the molecular biology and genetics of pathogens and their hosts in the context of improving the understanding and control of infectious diseases.
Aspects of pathogen biology of interest include:
- determining the basic mechanisms of infection of globally important pathogens
- deciphering the genetic diversity of selected disease agents in natural populations and determining its epidemiological impact
- studying immune evasion mechanisms
- exploiting parasitic, bacterial and viral pathogens as model biological systems
- developing practical applications including improved diagnostic tests and the identification and characterisation of vaccine candidates and drug targets
Research focuses on three main groups of pathogens:
- bacteria (Acinetobacter baumannii, Actinobacillus pleuropneumoniae, Burkholderia pseudomallei, Campylobacter jejuni, Clostridium difficile, Francisella tularensis, Helicobacter pylori, Haemphilus parasuis, Mycobacterium leprae, Mycoplasma hyopneumoniae, Mycobacterium tuberculosis, Staphylococcus aureus, Streptococcus suis, Streptococcus pneumonia, Yersinia enterocolitica, Yersinia pseudotuberculosis
- parasites (Entamoeba histolytica, Leishmania donovani, Plasmodium falciparum, Plasmodium knowlesi, Plasmodium vivax, Plasmodium berghei, Trypanosoma brucei,Trypanosoma cruzi
- viruses (African horse sickness, bluetongue, dengue, epizootic haemorrhagic disease, human herpesvirus 6, human cytomegalovirus, influenza, SARS)
Publications by department staff can be viewed in the School’s online repository.