Leverhulme centre for integrative research on agriculture and health
Lead: Alan Dangour
The LCIRAH is a centre dedicated to integrating research in agriculture and health, seeking answers to the question “How do we achieve sustainable food and agriculture systems which promote health and well being for all people?”
Older people and enhanced neurocognitive function study
Lead: Alan Dangour
The OPEN study aims to assess whether increased dietary intake of crystalline vitamin B12 will improve nerve function and cognitive function in older people with defined low vitamin B12 status.
REPAIR and ERICCA trials
Lead: Tim Clayton
The REPAIR trial aims (Renal protection against ischaemia reperfusion injury in transplantation) to determine if remote ischaemic preconditioning (RIPC) improves renal function after transplantation. The ERICCA trial (Effect of Remote Ischaemic preConditioning on clinical outcomes in patients undergoing Coronary Artery Bypass Graft surgery) aims to determine whether remote ischaemic preconditioning (RIC) improves clinical outcomes after cardiac surgery.
Improving the assessment and treatment of childhood obesity
Lead: Sanjay Kinra
Lead: Catherine Falconer
As part of the PROMISE Programme, two projects based at LSHTM aim to:
- Scope the impact of the National Child Measurement Programme feedback on the child obesity pathway; and
- Develop a new electronic tool to improve childhood obesity management in primary care.
Nutritional challenges, abdominal adiposity and type 2 diabetes in Indians
Lead: Hannah Kuper
This study was undertaken in Hyderabad, India, to assess the impact of early life nutritional supplementation and later life rural-urban migration on diabetes and other chronic diseases.
Epidemiology of infections amongst people with chronic kidney disease and diabetes
Lead: Dorothea Nitsch
Lead: Helen McDonald
Lead: Sara Thomas
Using routine health records, this project investigates whether people with diabetes who also have chronic kidney disease are at a higher risk of infections than those without kidney disease, and whether people with kidney disease receive vaccinations for vaccine-preventable diseases.
Exploring early and life-course determinants of chronic kidney disease
Lead: Dorothea Nitsch
The project uses data from the 1946 birth cohort study to investigate the pathways by which low birthweight, social disadvantage, and overweight throughout life are associated with markers of chronic kidney disease at age 60-4 years. Lifelong Health and Ageing cohort study
The course and outcome of alcohol use disorders (AUD): A population based cohort study in Goa, India
Lead: Vikram Patel
Lead: Abhijit Nadkarni
The broad aim of this study is to describe the longitudinal history and impact of alcohol use disorders, and their incidence, in a representative sample of adult men in Goa, India. We use a retrospective cohort design. Project description | SAAHAS 2 website
Using computerised clinical data to investigate the links between long-term drug treatments and cancer risk
Lead: Krishnan Bhaskaran
NIHR postdoctoral fellow
There are concerns that some widely-used drug treatments might be linked to an increase in the risk of cancer. The aim of the project is to investigate such concerns making use of routinely collected data on large numbers of patients observed over a number of years, recorded in electronic healthcare databases.
Community-based Hypertension Improvement Program (ComHIP)
The Centre for Global NCD of the LSHTM is leading the evaluation and cost-effective analysis of a community-based hypertension program (ComHIP) in a district in Ghana as an important contribution to the development of evidence-based innovative approaches to the management of non-communicable diseases in low & middle income countries.
ComHIP is a community based-program that engages both the public and private sectors in the community to improve the management and control of hypertension in the Lower Manya Krobo district. It aims to enhance the capacity of the Ghana Health Service through task shifting and innovative technology solutions to improve access to quality and affordable services for hypertension and other cardiovascular diseases (CVDs). The project also aims to improve the capacity of patients in managing their own conditions and risk factors.
For this project LSHTM is partnering with the Ghana Health Service, FHI360, School of Public Health of the University of Ghana and the Novartis Foundation.