Adapting the Good School Toolkit for secondary schools
Adapting a complex violence prevention intervention.
AMBITION (High Dose AMBISOME on a Fluconazole Backbone for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: A Randomised Controlled Non-inferiority Trial) is a four-year project funded at just under €10M by the European and Developing Countries Clinical Trials Partnership, the Swedish International Development Agency and the DFID/MRC/Wellcome Trust Joint Global Health Trials Fund. It runs from 1 January 2017 – 31 December 2020 across a consortium of five European and six African partners.
AMR and Unregistered Medicine Sellers in Cambodia
Understand & develop strategies to address unresolved challenges relating to governance of a poorly characterised segment of the health system - unregulated, for-profit drug sellers.
Andra Pradesh Children and Parents Study (APCaPS)
The Andhra Pradesh Children and Parent Study (APCAPS) is a large prospective, intergenerational cohort study in Southern India that began with the long-term follow-up of the Hyderabad Nutrition Trial (1987-1990). It is situated in 29 villages near the city of Hyderabad in Ranga Reddy district, Andhra Pradesh.
Anti-fibrinolytics Trialists Collaboration
The Anti-fibrinolytics Trialists Collaboration (ATC) is an international collaboration to conduct individual patient data meta-analyses of results from randomised trials of anti-fibrinolytics versus placebo.
Anti-Microbials in Society (AMIS) Programme
Fresh approaches to the study of antimicrobials in society.
Using Big Data to Identify Opportunities for Disease Prevention after Cancer.
Bilharzia and HIV (BILHIV)
Former England rugby players taking part in major study to investigate effects of the sport on brain health.
Care & prevent: skin infections and kidney disease
Contexts of Violence in Adolescence Cohort Study (CoVAC)
Understanding how family, peer, school and community contexts affect children’s experience of violence in adolescence and early adulthood.
Seeking to measure and solve the mystery of a kidney disease epidemic which is leading to the premature deaths of thousands of young people in low and middle income countries.
DREAMS Impact Evaluation
Designing Impact Evaluation studies of the Determined, Resilient, Empowered, AIDS-free, Mentored, and Safe (DREAMS) Partnership.
Drug resistance maps
The purpose of this project is to map the geographical distribution of resistance mutations in African Plasmodium falciparum malaria.
The Ebola vaccine projects – EBOVAC1, EBOVAC2, EBODAC and EBOMAN – are a series of trials and associated projects which aim to assess a novel prime-boost preventive vaccine regimen against Ebola Virus Disease (EVD).
The Erythema Nodosum Leprosum International Study (ENLIST) group is an international partnership between seven countries focused on improving the understanding and treatment of Erythema nodosum leprosum (ENL).
Entebbe Mother and Baby study
The Entebbe Mother and Baby Study (EMaBS) is a unique birth cohort, on-going in Africa.
Effect of Remote Ischaemic Conditioning on clinical outcomes in ST-segment elevation myocardial infarction patients undergoing Primary Percutaneous Coronary Intervention (ERIC-PPCI).
Febrile Illness Evaluation in a Broad Range of Endemicities (FIEBRE)
FIEBRE aims to reveal leading causes of fever in sub-Saharan Africa and southeast Asia. What are the main infections causing fever in children and adults, and how should they be treated?
Forms of Care
The Forms of Care Project is an ESRC-funded three-year ethnographic study examining instances where healthcare care staff within one medical trust and focusing on the palliative care team, either individually or collectively, do not do something. We acknowledge that paradoxically, this mode of ‘not intervening’ is, from the palliative team’s standpoint, a valid and important variant of medical intervention, yet is regularly perceived as withholding or denying the patient services or treatment.
Investigating genetic mechanisms underlying attractiveness of humans to mosquitoes.
Global Child Eye Health Project
Eye Health is essential to Child Health. We work to ensure that all children are getting access to eye health services to ensure they have the best vision possible.
Hararghe Health Research Partnership
Developing surveillance and research in Eastern Ethiopia to improve maternal and child health.
Health Reform Evaluation Programme (HREP)
The Health Reform Evaluation Programme (HREP) is a recently completed programme of research to evaluate the English NHS reforms set out in the Department of Health publication Health Reform in England: update and next steps.
The Health Economics MOdelling of Blood Donation study (the HEMO study) aims to determine the cost-effectiveness of the different ways of maintaining the future supply of blood to the NHS.
HIV Self-Testing Africa (STAR) Project
The UNITAID/PSI HIV Self-Testing Africa (STAR) Project is a four-year initiative to catalyse the market for HIV self-testing.
IDEAS aims to improve the health and survival of mothers and babies through generating evidence to inform policy and practice. Working in Ethiopia, North-Eastern Nigeria and the state of Uttar Pradesh in India, IDEAS uses measurement, learning and evaluation to find out what works, why and how in maternal and newborn health programmes.
Improving General Practice Services (IGPS)
Investigating quality improvement in general practices – what do they do and how do they do it? A survey of GPs and Practice Managers.
Partnership to support the control and elimination of visceral leishmaniasis in six countries, three in Asia (India, Nepal and Bangladesh) and three in Africa (Ethiopia, Sudan and South Sudan).
LINEA: Learning Initiative on Norms, Exploitation and Abuse
Exploring the potential of communities and social norms to prevent violence against and exploitation of children and adolescents.
Strengthening the use of data for malaria decision making in Africa.
Liver transplantation as a treatment for hepatocellular carcinoma
Investigating the best use of liver transplantation to treat patient’s with hepatocellular carcinoma (HCC).
Long-term follow-up of the ARTISTIC and Manchester cervical screening cohorts
Malaria Zero is an alliance of partners with one bold goal: to eliminate malaria from the island of Hispaniola by 2020.
Meta-analysis, Complexity and Heterogeneity (MACH)
Our research aims to develop new guidance for systematic reviewers when making a decision about whether or not to use a meta-analytical approach to the synthesis of quantitative evidence, with a particular emphasis on the synthesis of studies of complex interventions.
MONKEYBAR is a project seeking to identify risk factors and control strategies for Plasmodium knowlesi, a zoonotic malaria carried by macaques.
National Chronic Kidney Disease Audit (NCKDA)
National Survey of Sexual Attitudes and Lifestyles (Natsal)
Revealing the changing sexual attitudes and behaviour of the British population, Natsal is one of the largest scientific studies of sexual health and lifestyles in the world.
Occupational Kidney Disease in Pacific Coast Central America
There is a mystery epidemic of Chronic kidney disease of unknown cause (CKDu) affecting agricultural and non-agricultural communities in Mesoamerica. This disease has reduced the life expectancy of thousands and caused the deaths of tens of thousands young males and females.
Open Data Kit is a suite of state of the art electronic data capture tools.
Patient and Public Engagement
Advancing healthcare knowledge through patient and public involvement.
Patient reported outcome measures (PROMs)
Patients’ views are essential to achieving high-quality health care. Our PROMs research is helping to improve patient care by evaluating the performance of health care providers and guiding NHS reforms.
Peace Building in Cote d’Ivoire: Formative evaluation
Pilot Trial of Good School Toolkit for secondary schools
Pilot RCT of a complex violence prevention intervention.
Placing the Public in Public Health: Public Health in Britain, 1948-2010
This project is funded by a Wellcome Trust Medical Humanities New Investigator Award, awarded to Dr Alex Mold in 2013 and is based in the Centre for History in Public Health at the LSHTM.
A major study in South Africa and Zambia to test a new approach to the prevention and control of HIV in Africa.
Praziquantel in Preschool Children (PIP trial)
The Praziquantel in Preschoolers trial (PIP) aims to find the right treatment dose of praziquantel for preschool children living with intestinal schistosomiasis in Uganda.
A randomised double-blind controlled phase III study to compare the efficacy and safety of intravenous ferric carboxymaltose with placebo in patients with anaemia undergoing major open abdominal surgery.
Protecting children with disabilities
Protecting children with disabilities.
Research capacity strengthening and knowledge generation to support preparedness and response to humanitarian crises and epidemics.
Renal protection against ischaemia-reperfusion in transplantation: a randomised double blind placebo-controlled trial of 400 living-donor renal transplant patients.
Multicentre prospective randomised open controlled trial aiming to evaluate the efficacy and safety of percutaneous coronary intervention compared to optimal medical therapy alone for ischaemic left ventricular dysfunction.
A randomised controlled trial of an intervention delivered by mobile phone messaging to reduce sexually transmitted infections (STI) by increasing sexual health precaution behaviours in young people.
The Sustainable Evaluation through Analysis of Routinely Collected HIV data (SEARCH) is a collaboration between the London School of Hygiene & Tropical Medicine and the Ministries of Health in Malawi, Tanzania and Zambia, and is funded by the Bill & Melinda Gates Foundation.
SPRING for MDG’s (Sustainable Program Incorporating Nutrition and Games) is a seven year research programme funded by the Wellcome Trust that brings together researchers from the UK, India and Pakistan.
Stronger-SAFE: Eliminating trachoma in Ethiopia
200 million people still live in trachoma-endemic regions and are at risk of becoming blind despite concerted international effort to tackle the disease. With the clock ticking towards the 2020 elimination goal, novel strategies are urgently needed to accelerate and strengthen the SAFE strategy.
Surgical Care for Female Urinary Incontinence Project (UIP)
This research project aims to improve surgical services for women with urinary incontinence in England.
Sustainable and Healthy Food Systems (SHEFS)
SHEFS is a programme aiming to provide policy makers with novel, interdisciplinary evidence to define future food systems policies that deliver nutritious and healthy foods in an environmentally sustainable and socially equitable manner.
A five-year programme of research and evaluation funded by the UK Department of International Development (DFID). SWiFT assesses, evaluates and informs the International Labour Organisation’s DFID-funded “Work in Freedom” multi-country intervention to minimise women’s vulnerability to labour trafficking in South Asia and the Middle East.
The Fifth Child Project
The value and unexpected by-product of a community engagement strategy aimed at addressing the immunisation gap in north-west Ethiopia.
The Global Vector Hub
The Global Vector Hub is an open access, interactive resource that not only has the capacity to transform vector research and vector control programmes, but revolutionise our preparedness and ability to respond quickly and effectively to vector-borne disease outbreaks, around the world.
The Good Schools Study
Reducing violence in Ugandan primary schools.
The RifT Study - improving diagnosis and treatment of TB meningitis
M. tuberculosis is a leading cause of meningitis in people living with HIV. Currently, over 50% of cases die and many survivors are left disabled. Finding better diagnostics and optimised treatments is a priority.
The sixteen18 project
Exploring young people’s sexual practices in the UK.
This Sickle Cell Life
This collaborative research project, funded by the National Institute for Health Research (NIHR), Health Services and Delivery Research Programme, examines the experiences of young people with sickle cell as they transition to adulthood and move from using child to adult services.
Tight K is a feasibility study investigating how potassium levels are controlled following cardiac surgery.
The TREATS project (Tuberculosis Reduction through Expanded Antiretroviral Treatment and Screening for active TB) will measure the impact of a combined TB and HIV intervention – of population level active case-finding for TB, combined with universal testing and treatment for HIV -- on TB incidence, prevalence and incidence of infection when delivered to the entire population of 14 urban, high-prevalence communities in South Africa and Zambia.
The effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage: an international, randomised, double-blind, placebo-controlled trial.
UK Public Health Rapid Support Team (UK-PHRST)
A specialist team ready to respond to disease outbreaks around the world before they develop into health emergencies. The team also conducts rigorous operational research to improve epidemic preparedness.
Utoto Salaama/Peaceful Childhood
Understanding and preventing sexual and other forms of violence against children in Zanzibar.
Our overall aim is to support decision-making about the choice or modification of vaccination schedules at international, regional and country levels.
The WOMAN trial, coordinated by the London School of Hygiene & Tropical Medicine (LSHTM) Clinical Trials Unit (CTU) is an international clinical trial of the effect of tranexamic acid on death, hysterectomy and other maternal outcomes, in women with PPH.14.
World AsthmaPhenotypes Study (WASP)
The World AsthmaPhenotypes Study (WASP) aims to better understand and characterise different sub-types (phenotypes) of asthma.
ZikaPLAN (Preparedness Latin America Network) at LSHTM
A multinational and multidisciplinary consortium implementing critical research on the existing Zika virus outbreak whilst preparing a sustainable response capacity for future emerging epidemics in Latin America.