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A

Adapting the Good School Toolkit for secondary schools

Adapting a complex violence prevention intervention.

AMBITION

AMBITION (High Dose AMBISOME on a Fluconazole Backbone for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: A Randomised Controlled Non-inferiority Trial) is a four-year project funded at just under €10M by the European and Developing Countries Clinical Trials Partnership, the Swedish International Development Agency and the DFID/MRC/Wellcome Trust Joint Global Health Trials Fund. It runs from 1 January 2017 – 31 December 2020 across a consortium of five European and six African partners.

Meningitis
HIV/AIDS
Clinical trials

AMR and Unregistered Medicine Sellers in Cambodia

Understand & develop strategies to address unresolved challenges relating to governance of a poorly characterised segment of the health system - unregulated, for-profit drug sellers.

Andra Pradesh Children and Parents Study (APCaPS)

The Andhra Pradesh Children and Parent Study (APCAPS) is a large prospective, intergenerational cohort study in Southern India that began with the long-term follow-up of the Hyderabad Nutrition Trial (1987-1990).  It is situated in 29 villages near the city of Hyderabad in Ranga Reddy district, Andhra Pradesh.

Cardiovascular disease
Chronic disease
Diabetes
Non-communicable diseases
Obesity
Adolescent health
Food
Physical activity
Social and structural determinants of health
Urbanisation
South Asia
India
Epidemiology
Genetic epidemiology
GIS/Spatial analysis
Life-course epidemiology
Nutrition

Anti-fibrinolytics Trialists Collaboration

The Anti-fibrinolytics Trialists Collaboration (ATC) is an international collaboration to conduct individual patient data meta-analyses of results from randomised trials of anti-fibrinolytics versus placebo.

Clinical trials

Anti-Microbials in Society (AMIS) Programme

Fresh approaches to the study of antimicrobials in society.

Infectious disease
Behaviour change
Drug resistance
Health promotion
Health systems
Social and structural determinants of health
Eastern Africa
Southeast Asia
Anthropology
Ethnography
History
Medicine
Sociology

B

BEYOND Cancer

Using Big Data to Identify Opportunities for Disease Prevention after Cancer.

Cancer
Cardiovascular disease
Mental health
Non-communicable diseases
Clinical databases
Electronic health records
England
United Kingdom
Europe
Epidemiology

Bilharzia and HIV (BILHIV)

HIV/AIDS
Diagnostics
Zambia
Epidemiology

BRAIN study

Former England rugby players taking part in major study to investigate effects of the sport on brain health.

Dementia
Neurological diseases
Rugby
Sport
Concussion
Ageing
Occupational health
Physical activity
Epidemiology

C

Care & prevent: skin infections and kidney disease

Addiction
Substance use
Mixed methods
Hygiene
Bacteria
London
United Kingdom
Public health
Social Sciences

Contexts of Violence in Adolescence Cohort Study (CoVAC)

Understanding how family, peer, school and community contexts affect children’s experience of violence in adolescence and early adulthood.

Violence
Adolescent health
Child health
Gender
Ethics
Epidemiology

D

DEGREE study

Seeking to measure and solve the mystery of a kidney disease epidemic which is leading to the premature deaths of thousands of young people in low and middle income countries.

DREAMS Impact Evaluation

Evaluating the impact of the Determined, Resilient, Empowered, AIDS-free, Mentored, and Safe (DREAMS) Partnership

Drug resistance maps

The purpose of this project is to map the geographical distribution of resistance mutations in African Plasmodium falciparum malaria.

E

EBOVAC

The Ebola vaccine projects – EBOVAC1, EBOVAC2, EBODAC and EBOMAN – are a series of trials and associated projects which aim to assess a novel prime-boost preventive vaccine regimen against Ebola Virus Disease (EVD).

Emerging and Pandemic diseases
Infectious disease
Zoonotic disease
Clinical trials
Drug discovery and development
Immunisation
Vaccines
Eastern Africa
Western Africa
Europe
Tanzania
Kenya
Anthropology
Immunology
Mathematical modelling
Vaccinology

ENLIST

The Erythema Nodosum Leprosum International Study (ENLIST) group is an international partnership between seven countries focused on improving the understanding and treatment of Erythema nodosum leprosum (ENL).

Entebbe Mother and Baby study

The Entebbe Mother and Baby Study (EMaBS) is a unique birth cohort, on-going in Africa.

ERIC PPCI

Effect of Remote Ischaemic Conditioning on clinical outcomes in ST-segment elevation myocardial infarction patients undergoing Primary Percutaneous Coronary Intervention (ERIC-PPCI).

F

Febrile Illness Evaluation in a Broad Range of Endemicities (FIEBRE)

FIEBRE aims to reveal leading causes of fever in sub-Saharan Africa and southeast Asia. What are the main infections causing fever in children and adults, and how should they be treated?

Fever
Non-malarial fever
Febrile illness
Infectious disease
Antimicrobial resistance
Drug resistance
Diagnostics
Bacteria
Malawi
Mozambique
Zimbabwe
Myanmar
Lao PDR
Anthropology
Ethnography
Bacteriology
Epidemiology

Forms of Care

The Forms of Care Project is an ESRC-funded three-year ethnographic study examining instances where healthcare care staff within one medical trust and focusing on the palliative care team, either individually or collectively, do not do something. We acknowledge that paradoxically, this mode of ‘not intervening’ is, from the palliative team’s standpoint, a valid and important variant of medical intervention, yet is regularly perceived as withholding or denying the patient services or treatment.

Ethics
Health services research
Methodology
Research : policy relationship
Europe
United Kingdom
Anthropology
Sociology

G

GenoScent

Investigating genetic mechanisms underlying attractiveness of humans to mosquitoes.

Vector control
Malaria
Vector borne diseases
Worldwide
Entomology
Genetics
Vector biology

Global Child Eye Health Project

Eye Health is essential to Child Health. We work to ensure that all children are getting access to eye health services to ensure they have the best vision possible.

Eye diseases
Child health
Eye health
Tanzania
India
Public health
Health services

H

Hararghe Health Research Partnership

Developing surveillance and research in Eastern Ethiopia to improve maternal and child health.

Infectious disease
Emerging and Pandemic diseases
Child health
Maternal health
Neonatal health
Surveillance
Vaccines
Eastern Africa
Epidemiology
Anthropology
Medicine
GIS/Spatial analysis

Health Reform Evaluation Programme (HREP)

The Health Reform Evaluation Programme (HREP) is a recently completed programme of research to evaluate the English NHS reforms set out in the Department of Health publication Health Reform in England: update and next steps.

Health care policy
Health policy
Policy analysis

HEMO study

The Health Economics MOdelling of Blood Donation study (the HEMO study) aims to determine the cost-effectiveness of the different ways of maintaining the future supply of blood to the NHS.

Asthma
Cancer
Cardiovascular disease
Non-communicable diseases
Mental health
Clinical care
Electronic health records
Primary care
Worldwide
Epidemiology
Pharmacoepidemiology
Statistics

HIV Self-Testing Africa (STAR) Project

The UNITAID/PSI HIV Self-Testing Africa (STAR) Project is a four-year initiative to catalyse the market for HIV self-testing.

HIV/AIDS
Sexually transmitted diseases and infection
Clinical trials
Diagnostics
Economic evaluation
Health care policy
Quality improvement
Southern Africa
Malawi
Zambia
Zimbabwe
Economics
Epidemiology
Mathematical modelling

I

IDEAS

IDEAS aims to improve the health and survival of mothers and babies through generating evidence to inform policy and practice.  Working in Ethiopia, North-Eastern Nigeria and the state of Uttar Pradesh in India, IDEAS uses measurement, learning and evaluation to find out what works, why and how in maternal and newborn health programmes.

Child health
Maternal health
Ethiopia
India
Nigeria
Economics
Epidemiology
Statistics

Improving General Practice Services (IGPS)

Investigating quality improvement in general practices – what do they do and how do they do it? A survey of GPs and Practice Managers.

Primary care
Quality improvement
Organisational research
Health services research
United Kingdom
Management

K

KalaCORE

Partnership to support the control and elimination of visceral leishmaniasis in six countries, three in Asia (India, Nepal and Bangladesh) and three in Africa (Ethiopia, Sudan and South Sudan).

Neglected Tropical Diseases
Vector borne disease
Evaluation
Health systems
Outbreaks
Surveillance
Vector control
Eastern Africa
South Asia
Education
Parasitology
Vector biology

L

LINEA: Learning Initiative on Norms, Exploitation and Abuse

Exploring the potential of communities and social norms to prevent violence against and exploitation of children and adolescents.

Social Sciences

LINK programme

Strengthening the use of data for malaria decision making in Africa.

Infectious disease
Malaria
Neglected Tropical Diseases
Vector borne disease
Decision analysis
Evaluation
Health systems
Research : policy relationship
Surveillance
Eastern Africa
Middle Africa
Southern Africa
Western Africa
Economics
Epidemiology
GIS/Spatial analysis
Political science
Geospatial modelling

Liver transplantation as a treatment for hepatocellular carcinoma

Investigating the best use of liver transplantation to treat patient’s with hepatocellular carcinoma (HCC).

Long-term follow-up of the ARTISTIC and Manchester cervical screening cohorts

Human papillomavirus
Cancer

M

Malaria Zero

Malaria Zero is an alliance of partners with one bold goal: to eliminate malaria from the island of Hispaniola by 2020.

Meta-analysis, Complexity and Heterogeneity (MACH)

Our research aims to develop new guidance for systematic reviewers when making a decision about whether or not to use a meta-analytical approach to the synthesis of quantitative evidence, with a particular emphasis on the synthesis of studies of complex interventions.

MONKEYBAR

MONKEYBAR is a project seeking to identify risk factors and control strategies for Plasmodium knowlesi, a zoonotic malaria carried by macaques.

N

National Chronic Kidney Disease Audit (NCKDA)

National Survey of Sexual Attitudes and Lifestyles (Natsal)

Revealing the changing sexual attitudes and behaviour of the British population, Natsal is one of the largest scientific studies of sexual health and lifestyles in the world.

Adolescent health
Reproductive health
Sexual behaviour
Sexual health
Sexual function
Epidemiology

O

Occupational Kidney Disease in Pacific Coast Central America

There is a mystery epidemic of Chronic kidney disease of unknown cause (CKDu) affecting agricultural and non-agricultural communities in Mesoamerica. This disease has reduced the life expectancy of thousands and caused the deaths of tens of thousands young males and females.

ODK@LSHTM

Open Data Kit is a suite of state of the art electronic data capture tools.

Clinical trials
Electronic health records
Mobile technologies
Surveillance
Worldwide

ORCA

ORCA aims to improve the quality of health data in Ethiopia by supporting analysts  at the Federal Ministry of Health.

Malaria
Tuberculosis
Data analysis
Public health
Maternal health
Neonatal health
Quantitative methods
Health systems
Nutrition
Epidemiology
Public health

P

Patient and Public Engagement

Advancing healthcare knowledge through patient and public involvement.

Patient reported outcome measures (PROMs)

Patients’ views are essential to achieving high-quality health care. Our PROMs research is helping to improve patient care by evaluating the performance of health care providers and guiding NHS reforms.

Peace Building in Cote d’Ivoire: Formative evaluation

Pilot Trial of Good School Toolkit for secondary schools

Pilot RCT of a complex violence prevention intervention.

Behaviour change
Implementation research
Mental health
Violence
Child health
Adolescent health
Complex interventions
Clinical trials
Uganda
Eastern Africa
Epidemiology
Public health
Social science
Anthropology
Psychology

Placing the Public in Public Health: Public Health in Britain, 1948-2010

This project is funded by a Wellcome Trust Medical Humanities New Investigator Award, awarded to Dr Alex Mold in 2013 and is based in the Centre for History in Public Health at the LSHTM.

Addiction
Cancer
Infectious disease
Non-communicable diseases
Obesity
Behaviour change
Social and structural determinants of health
Health promotion
Physical activity
Research : policy relationship
Europe
United Kingdom
Epidemiology
History
Policy analysis
Social Policy
Sociology

PopART

A major study in South Africa and Zambia to test a new approach to the prevention and control of HIV in Africa.

HIV/AIDS
Infectious disease
Tuberculosis
Clinical trials
Complex interventions
Evaluation
Implementation research
Southern Africa
South Africa
Zambia
Economics
Epidemiology
Mathematical modelling
Social science
Phylogenetics

Praziquantel in Preschool Children (PIP trial)

The Praziquantel in Preschoolers trial (PIP) aims to find the right treatment dose of praziquantel for preschool children living with intestinal schistosomiasis in Uganda.

PREVENTT

A randomised double-blind controlled phase III study to compare the efficacy and safety of intravenous ferric carboxymaltose with placebo in patients with anaemia undergoing major open abdominal surgery.

Protecting children with disabilities

Protecting children with disabilities.

Disability
Mental health
Violence
Child health
Adolescent health
Social and structural determinants of health
Mixed methods
Uganda
Malawi
Eastern Africa
Southern Africa
Epidemiology
Public health
Social science
Anthropology
Psychology

R

RECAP

Research capacity strengthening and knowledge generation to support preparedness and response to humanitarian crises and epidemics.

REPAIR

Renal protection against ischaemia-reperfusion in transplantation: a randomised double blind placebo-controlled trial of 400 living-donor renal transplant patients.

REVIVED

Multicentre prospective randomised open controlled trial aiming to evaluate the efficacy and safety of percutaneous coronary intervention compared to optimal medical therapy alone for ischaemic left ventricular dysfunction.

Rohingya Adolescent Research Network

s

safetxt

A randomised controlled trial of an intervention delivered by mobile phone messaging to reduce sexually transmitted infections (STI) by increasing sexual health precaution behaviours in young people.

S

SEARCH

The Sustainable Evaluation through Analysis of Routinely Collected HIV data (SEARCH) is a collaboration between the London School of Hygiene & Tropical Medicine and the Ministries of Health in Malawi, Tanzania and Zambia, and is funded by the Bill & Melinda Gates Foundation.

SPRING

SPRING for MDG’s (Sustainable Program Incorporating Nutrition and Games)  is a seven year research programme funded by the Wellcome Trust that brings together researchers from the UK, India and Pakistan.

Stronger-SAFE: Eliminating trachoma in Ethiopia

200 million people still live in trachoma-endemic regions and are at risk of becoming blind despite concerted international effort to tackle the disease. With the clock ticking towards the 2020 elimination goal, novel strategies are urgently needed to accelerate and strengthen the SAFE strategy.

Trachoma
Eye diseases
Neglected Tropical Diseases
Infectious disease
Behaviour change
Clinical trials
Hygiene
Sanitation
Vector control
Ethiopia
Entomology
Epidemiology
Genomics
Mathematical modelling
Social science

Surgical Care for Female Urinary Incontinence Project (UIP)

This research project aims to improve surgical services for women with urinary incontinence in England.

Sustainable and Healthy Food Systems (SHEFS)

SHEFS is a programme aiming to provide policy makers with novel, interdisciplinary evidence to define future food systems policies that deliver nutritious and healthy foods in an environmentally sustainable and socially equitable manner.

SWiFT

A five-year programme of research and evaluation funded by the UK Department of International Development (DFID). SWiFT assesses, evaluates and informs the International Labour Organisation’s DFID-funded “Work in Freedom” multi-country intervention to minimise women’s vulnerability to labour trafficking in South Asia and the Middle East.

Behaviour change
Implementation research
Missing data
Capacity Building
Migration
Gender
Violence
Behaviour change
Global Health
South Asia
India
Public health
Health services
Social Sciences
Social Policy
Programme evaluation

T

The Confronting Obesity: Co-creating policy with youth (Co-Create)

Co-Create is a project designed to reduce obesity and its co-morbidities by working with adolescents, to create, inform and disseminate obesity-preventive, evidence-based policies, using a complex systems approach.

The Fifth Child Project

The value and unexpected by-product of a community engagement strategy aimed at addressing the immunisation gap in north-west Ethiopia.

Infectious disease
Child health
Evaluation
Immunisation
Vaccines
Community engagement
Eastern Africa
Ethiopia
Programme evaluation
Qualitative evaluation
Public health
Health services

The Global Vector Hub

The Global Vector Hub is an open access, interactive resource that not only has the capacity to transform vector research and vector control programmes, but revolutionise our preparedness and ability to respond quickly and effectively to vector-borne disease outbreaks, around the world.

The Good Schools Study

Reducing violence in Ugandan primary schools.

Behaviour change
Implementation research
Mental health
Violence
Child health
Adolescent health
Complex interventions
Clinical trials
Uganda
Eastern Africa
Epidemiology
Public health
Social science
Anthropology
Psychology

The RifT Study - improving diagnosis and treatment of TB meningitis

M. tuberculosis is a leading cause of meningitis in people living with HIV. Currently, over 50% of cases die and many survivors are left disabled. Finding better diagnostics and optimised treatments is a priority.

The sixteen18 project

Exploring young people’s sexual practices in the UK.

This Sickle Cell Life

This collaborative research project, funded by the National Institute for Health Research (NIHR), Health Services and Delivery Research Programme, examines the experiences of young people with sickle cell as they transition to adulthood and move from using child to adult services.

Tight K

Tight K is a feasibility study investigating how potassium levels are controlled following cardiac surgery.

Cardiovascular disease
Clinical care
Clinical trials
United Kingdom

TREATS Project

The TREATS project (Tuberculosis Reduction through Expanded Antiretroviral Treatment and Screening for active TB) will measure the impact of a combined TB and HIV intervention – of population level active case-finding for TB, combined with universal testing and treatment for HIV -- on TB incidence, prevalence and incidence of infection when delivered to the entire population of 14 urban, high-prevalence communities in South Africa and Zambia.

TXA

The effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage: an international, randomised, double-blind, placebo-controlled trial.

U

UK Public Health Rapid Support Team (UK-PHRST)

A specialist team ready to respond to disease outbreaks around the world before they develop into health emergencies. The team also conducts rigorous operational research to improve epidemic preparedness.

Outbreaks
Implementation research
Diagnostics
Hygiene & Sanitation
Vector control
Emerging & Pandemic Diseases
Infectious Diseases
Vector borne diseases
Diarrhoea
Zoonotic diseases
Worldwide
Operational research
Epidemiology
Anthropology
Virology
GIS/Spatial analysis

Umoya omuhle

Tuberculosis
Hospital acquired infection
Behaviour change
Design thinking
Implementation research
Health services research
Public health
Social and structural determinants of health
Infectious disease policy
Infectious Diseases
South Africa
Southern Africa
Public health
Health services
Mathematical modelling
Social Sciences

Utoto Salaama/Peaceful Childhood

Understanding and preventing sexual and other forms of violence against children in Zanzibar.

Behaviour change
Implementation research
Mental health
Violence
Child health
Adolescent health
Complex interventions
Clinical trials
Tanzania
Eastern Africa
Epidemiology
Public health
Social science
Anthropology
Psychology

V

Vaccine Schedules

Our overall aim is to support decision-making about the choice or modification of vaccination schedules at international, regional and country levels.

W

Woman Trial

The WOMAN trial, coordinated by the London School of Hygiene & Tropical Medicine (LSHTM) Clinical Trials Unit (CTU) is an international clinical trial of the effect of tranexamic acid on death, hysterectomy and other maternal outcomes, in women with PPH.14.

World AsthmaPhenotypes Study (WASP)

The World AsthmaPhenotypes Study (WASP) aims to better understand and characterise different sub-types (phenotypes) of asthma.

Asthma

Z

ZikaPLAN (Preparedness Latin America Network) at LSHTM

A multinational and multidisciplinary consortium implementing critical research on the existing Zika virus outbreak whilst preparing a sustainable response capacity for future emerging epidemics in Latin America.

Vector borne disease
Vector borne diseases
Worldwide
Epidemiology