Adapting the Good School Toolkit for secondary schools
Adapting a complex violence prevention intervention.
Addressing quality in the private healthcare sector – a randomised controlled trial of the SafeCare Quality Improvement Programme in Tanzania
SafeCare is a quality improvement model developed by the NGO PharmAccess, aimed at lower-level public and private health facilities in sub-Saharan Africa. The private sector is a major and growing source of care, but there are concerns about quality and safety, and these are insufficiently addressed by government regulation or international hospital accreditation standards. SafeCare was designed to address this gap, offering realistic setting-appropriate standards and stepwise certification, as well as access to credit for implementing improvements.
African Population History
Reconstructing Africa’s demographic past. Exploring new sources, methods and technologies to uncover long-term population trends.
AMBITION (High Dose AMBISOME on a Fluconazole Backbone for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: A Randomised Controlled Non-inferiority Trial) is a four-year project funded at just under €10M by the European and Developing Countries Clinical Trials Partnership, the Swedish International Development Agency and the DFID/MRC/Wellcome Trust Joint Global Health Trials Fund. It runs from 1 January 2017 – 31 December 2020 across a consortium of five European and six African partners.
Andra Pradesh Children and Parents Study (APCaPS)
The Andhra Pradesh Children and Parent Study (APCAPS) is a large prospective, intergenerational cohort study in Southern India that began with the long-term follow-up of the Hyderabad Nutrition Trial (1987-1990). It is situated in 29 villages near the city of Hyderabad in Ranga Reddy district, Andhra Pradesh.
Anthropology of Antimicrobial Resistance Research Group
We develop perspectives on antimicrobial resistance that draw from social theories about medicines, care, technologies, infrastructures, global arrangements on health, multi-species interactions, futures and more.
Anti-fibrinolytics Trialists Collaboration
The Anti-fibrinolytics Trialists Collaboration (ATC) is an international collaboration to conduct individual patient data meta-analyses of results from randomised trials of anti-fibrinolytics versus placebo.
Anti-Microbials in Society (AMIS) Programme
Fresh approaches to the study of antimicrobials in society.
Using Big Data to Identify Opportunities for Disease Prevention after Cancer.
BHF PROTECT-TAVI is a research study examining the effect of cerebral embolic protection devices on the risk of stroke in patients undergoing Transcatheter Aortic Valve Implantation for aortic stenosis.
Bilharzia and HIV (BILHIV)
Former England rugby players are taking part in a major study to investigate the sport's effects on brain health.
Capacity Sharing for AntiMicrobial Stewardship (CaSAMS)
Care & prevent: skin infections and kidney disease
Promoting skin & soft tissue infection care and preventing AA amyloidosis among people who inject drugs in the UK.
Child-friendly Catholic Schools Study in Zimbabwe (CCSS-Z)
CCSS-Z is a mixed-methods study that works with partners in Zimbabwe to support the design and intervention of a child safeguarding intervention in Catholic Primary schools. The study consists of qualitative research being conducted alongside the development of the intervention, a process evaluation, and an impact evaluation.
Combating drug resistance through better governance of informal antibiotic sellers in Cambodia
Contexts of Violence in Adolescence Cohort Study (CoVAC)
Understanding how family, peer, school and community contexts affect children’s experience of violence in adolescence and early adulthood.
Dagu aims to develop Ethiopian excellence in public health evaluation and improve quality and utilisation of primary and community-based health care services.
DecodeME is the largest-ever DNA study of Myalgic Encephalomyelitis, or Chronic Fatigue Syndrome (ME/CFS). It will recruit 20,000 people for biomedical research into the causes of the disease.
Seeking to measure and solve the mystery of a kidney disease epidemic which is leading to the premature deaths of thousands of young people in low and middle income countries.
DREAMS Impact Evaluation
Evaluating the impact of the Determined, Resilient, Empowered, AIDS-free, Mentored, and Safe (DREAMS) Partnership
Drug resistance maps
The purpose of this project is to map the geographical distribution of resistance mutations in African Plasmodium falciparum malaria.
The Ebola vaccine projects – EBOVAC1, EBOVAC2, EBODAC and EBOMAN – are a series of trials and associated projects which aim to assess a novel prime-boost preventive vaccine regimen against Ebola Virus Disease (EVD).
The Erythema Nodosum Leprosum International STudy (ENLIST) group is an international partnership between seven countries focused on improving the understanding and treatment of Erythema nodosum leprosum (ENL).
Entebbe Mother and Baby study
The Entebbe Mother and Baby Study (EMaBS) is a unique birth cohort, on-going in Africa.
Effect of Remote Ischaemic Conditioning on clinical outcomes in ST-segment elevation myocardial infarction patients undergoing Primary Percutaneous Coronary Intervention (ERIC-PPCI).
Research question: how effective and cost-effective is emergency surgery for patients with common acute conditions presenting as emergency admissions to NHS hospitals.
Febrile Illness Evaluation in a Broad Range of Endemicities (FIEBRE)
FIEBRE aims to reveal leading causes of fever in sub-Saharan Africa and southeast Asia. What are the main infections causing fever in children and adults, and how should they be treated?
Forms of Care
The Forms of Care project ethnographically examines practices of ‘not doing’ in UK palliative care practice, and how these may nevertheless be an active and valuable form of care.
Investigating genetic mechanisms underlying attractiveness of humans to mosquitoes.
Global Child Eye Health Project
Eye Health is essential to Child Health. We work to ensure that all children are getting access to eye health services to ensure they have the best vision possible.
Supporting government and partners in strengthening health systems for better mental health of Syrian refugees and host communities in Lebanon.
Hararghe Health Research Partnership
Developing surveillance and research in Eastern Ethiopia to improve maternal and child health.
Former football players are taking part in a major study to investigate effects of the sport on brain health.
Health Reform Evaluation Programme (HREP)
The Health Reform Evaluation Programme (HREP) is a recently completed programme of research to evaluate the English NHS reforms set out in the Department of Health publication Health Reform in England: update and next steps.
The Health Economics MOdelling of Blood Donation study (the HEMO study) aims to determine the cost-effectiveness of the different ways of maintaining the future supply of blood to the NHS.
HIV Self-Testing Africa (STAR) Project
The UNITAID/PSI HIV Self-Testing Africa (STAR) Project is a four-year initiative to catalyse the market for HIV self-testing.
Homeless Health Peer Advocacy Evaluation
Evaluating the impact of Peer Advocates on the use of health care for adults in London who are homeless.
IAC-CKD: Improving acute cardiac care for patients with kidney disease through linkage of national audits in the UK
We are focused on improving outcomes for people with kidney and cardiovascular disease in the UK.
IDEAS aims to improve the health and survival of mothers and babies through generating evidence to inform policy and practice. Working in Ethiopia, North-Eastern Nigeria and the state of Uttar Pradesh in India, IDEAS uses measurement, learning and evaluation to find out what works, why and how in maternal and newborn health programmes.
Improving General Practice Services (IGPS)
Investigating quality improvement in general practices – what do they do and how do they do it? A survey of GPs and Practice Managers.
Investigating the predictors of intimate partner violence: A mixed method longitudinal study in Tanzania
This mixed-method study combines a four-wave longitudinal quantitative design with qualitative interviews to explore the predictors of intimate partner violence in Mwanza, Tanzania.
Partnership to support the control and elimination of visceral leishmaniasis in six countries, three in Asia (India, Nepal and Bangladesh) and three in Africa (Ethiopia, Sudan and South Sudan).
LAMP4Yaws is a multi-country EDCTP-funded project, assessing the real-life accuracy of a new diagnostic test in yaws-endemic areas of Ghana, Côte d’Ivoire and Cameroon, to support WHO’s yaws eradication strategy.
LINEA: Learning Initiative on Norms, Exploitation and Abuse
Exploring the potential of communities and social norms to prevent violence against and exploitation of children and adolescents.
Strengthening the use of data for malaria decision making in Africa.
Liver transplantation as a treatment for hepatocellular carcinoma
Investigating the best use of liver transplantation to treat patient’s with hepatocellular carcinoma (HCC).
Long-term follow-up of the ARTISTIC and Manchester cervical screening cohorts
Malaria Zero is an alliance of partners with one bold goal: to eliminate malaria from the island of Hispaniola by 2020.
Meta-analysis, Complexity and Heterogeneity (MACH)
Our research aims to develop new guidance for systematic reviewers when making a decision about whether or not to use a meta-analytical approach to the synthesis of quantitative evidence, with a particular emphasis on the synthesis of studies of complex interventions.
Migration Gender Health Systems (MiGHS)
A research collaboration addressing pressing issues facing health systems globally and at a national level in South Africa – the impacts of and response to migration and its intersection with gender.
MONKEYBAR is a project seeking to identify risk factors and control strategies for Plasmodium knowlesi, a zoonotic malaria carried by macaques.
National Chronic Kidney Disease Audit (NCKDA)
National Survey of Sexual Attitudes and Lifestyles (Natsal)
Revealing the changing sexual attitudes and behaviour of the British population, Natsal is one of the largest scientific studies of sexual health and lifestyles in the world.
NIHR Public Health Policy Research Unit
The NIHR Public Health PRU (PH-PRU) conducts public health research with a social determinants focus.
Occupational Kidney Disease in Pacific Coast Central America
There is a mystery epidemic of Chronic kidney disease of unknown cause (CKDu) affecting agricultural and non-agricultural communities in Mesoamerica. This disease has reduced the life expectancy of thousands and caused the deaths of tens of thousands young males and females.
Open Data Kit is a suite of state of the art electronic data capture tools.
The OPT-SMC project supports national malaria control programmes in West and Central Africa to conduct implementation research on Seasonal Malaria Chemoprevention by providing grants and technical assistance, and facilitates sharing of information and expertise between countries. The project is a partnership between the national malaria control programmes in 13 countries.
ORCA aims to improve the quality of health data in Ethiopia by supporting analysts at the Ministry of Health, Ethiopia.
The Pathfinder Initiative, funded by the Wellcome Trust with support from the Oak Foundation, supports rapid progress towards a healthy, zero-carbon society.
Patient and Public Engagement
Advancing healthcare knowledge through patient and public involvement.
Patient Reported Outcome Measures (PROMs)
Patients’ views are essential to achieving high-quality healthcare. Our PROMs research is helping to improve patient care by evaluating the performance of health care providers and guiding NHS reforms.
Peace Building in Cote d’Ivoire: Formative evaluation
PENDA: Programme for Evidence to Inform Disability Action
PENDA is consortium lead by the International Centre for Evidence in Disability, it is focused on creating evidence to achieve long-term improved wellbeing and inclusion of people with disabilities in Low and Middle Income Country's (LMICs), through building knowledge, people and tools.
Investigating the effectiveness of different treatments for Type 2 Diabetes Mellitus.
Pilot Trial of Good School Toolkit for secondary schools
Pilot RCT of a complex violence prevention intervention.
Placing the Public in Public Health: Public Health in Britain, 1948-2010
This project is funded by a Wellcome Trust Medical Humanities New Investigator Award, awarded to Dr Alex Mold in 2013 and is based in the Centre for History in Public Health at the LSHTM.
A major study in South Africa and Zambia to test a new approach to the prevention and control of HIV in Africa.
How people respond to vaccines, and how well they work, varies between populations. POPVAC’s goal is to understand these differences in order to identify strategies of improving vaccine effectiveness.
Praziquantel in Preschool Children (PIP trial)
The Praziquantel in Preschoolers trial (PIP) aims to find the right treatment dose of praziquantel for preschool children living with intestinal schistosomiasis in Uganda.
Preventing Violence Against Children in Schools (PVACS)
Training teachers on emotional self-regulation and positive discipline to prevent and reduce violence against children in schools in Nyarugusu refugee camp.
A randomised double-blind controlled phase III study to compare the efficacy and safety of intravenous ferric carboxymaltose with placebo in patients with anaemia undergoing major open abdominal surgery.
Promoting inclusion in decent work for Ugandan young people
Developing an evidence base and platform for action around how violence in childhood and adolescence affects child labour, participation in skills programmes and employment outcomes in Uganda.
Protecting children with disabilities
Protecting children with disabilities.
Research capacity strengthening and knowledge generation to support preparedness and response to humanitarian crises and epidemics.
Renal protection against ischaemia-reperfusion in transplantation: a randomised double blind placebo-controlled trial of 400 living-donor renal transplant patients.
Multicentre prospective randomised open controlled trial aiming to evaluate the efficacy and safety of percutaneous coronary intervention compared to optimal medical therapy alone for ischaemic left ventricular dysfunction.
Rohingya Adolescent Research Network
Romantic jealousy and IPV collaboration
Exploring infidelity, romantic jealousy and intimate partner violence.
A randomised controlled trial of an intervention delivered by mobile phone messaging to reduce sexually transmitted infections (STI) by increasing sexual health precaution behaviours in young people.
The Sustainable Evaluation through Analysis of Routinely Collected HIV data (SEARCH) is a collaboration between the London School of Hygiene & Tropical Medicine and the Ministries of Health in Malawi, Tanzania and Zambia, and is funded by the Bill & Melinda Gates Foundation.
Working in partnership across five institutions, we conduct multi-disciplinary research in Ghana and Ethiopia to improve experiences of severe and stigmatising neglected tropical diseases of the skin.
SPRING for MDG’s (Sustainable Program Incorporating Nutrition and Games) is a seven year research programme funded by the Wellcome Trust that brings together researchers from the UK, India and Pakistan.
Stronger-SAFE: Eliminating trachoma in Ethiopia
200 million people still live in trachoma-endemic regions and are at risk of becoming blind despite concerted international effort to tackle the disease. With the clock ticking towards the 2020 elimination goal, novel strategies are urgently needed to accelerate and strengthen the SAFE strategy.
SuNMaP 2 Longitudinal Study
We are assessing how UK funding to Support the National Malaria Programme in Nigeria is affecting change.
Surgical Care for Female Urinary Incontinence Project (UIP)
This research project aims to improve surgical services for women with urinary incontinence in England.
Sustainable and Healthy Food Systems (SHEFS)
SHEFS is a programme aiming to provide policy makers with novel, interdisciplinary evidence to define future food systems policies that deliver nutritious and healthy foods in an environmentally sustainable and socially equitable manner.
Sustainable Development Goal: Health & Wellbeing (SDG-HaW) Research Consortium
We conduct formative research into the health and wellbeing needs and priorities of host communities in which around 30 Anglo-American mines are situated, in eight countries.
A five-year programme of research and evaluation funded by the UK Department of International Development (DFID). SWiFT assesses, evaluates and informs the International Labour Organisation’s DFID-funded “Work in Freedom” multi-country intervention to minimise women’s vulnerability to labour trafficking in South Asia and the Middle East.
The Confronting Obesity: Co-creating policy with youth (Co-Create)
Co-Create is a project designed to reduce obesity and its co-morbidities by working with adolescents, to create, inform and disseminate obesity-preventive, evidence-based policies, using a complex systems approach.
The DE-grading Epidemiology (DEEP) Network
The DE-grading Epidemiology (DEEP) Network has been formed to encourage open debate about the use of algorithms to assess epidemiological studies, and maintain contacts between those of us who are working on these issues. It will pursue strategies to improve our ability to methodically and accurately integrate and interpret epidemiologic evidence.
The Fifth Child Project
The value and unexpected by-product of a community engagement strategy aimed at addressing the immunisation gap in north-west Ethiopia.
The Global Vector Hub
The Global Vector Hub is an open access, interactive resource. It has the capacity to transform vector research and vector control programmes, and to revolutionise our preparedness and ability to respond quickly and effectively to vector-borne disease outbreaks, around the world.
The Good Schools Study
Reducing violence in Ugandan primary schools.
The RifT Study - improving diagnosis and treatment of TB meningitis
M. tuberculosis is a leading cause of meningitis in people living with HIV. Currently, over 50% of cases die and many survivors are left disabled. Finding better diagnostics and optimised treatments is a priority.
The sixteen18 project
Exploring young people’s sexual practices in the UK.
This Sickle Cell Life
This collaborative research project, funded by the National Institute for Health Research (NIHR), Health Services and Delivery Research Programme, examines the experiences of young people with sickle cell as they transition to adulthood and move from using child to adult services.
Tight K is a study investigating how potassium levels are controlled following cardiac surgery.
TND: The test-negative design for COVID-19
This website is created to facilitate an informal network for researchers using the Test-Negative-Design (TND) for studying the causes of COVID-19 infection. We will create a repository of papers about the use of the TND, and for questionnaires for use in TND studies of the causes of COVID-19.
The TREATS project (Tuberculosis Reduction through Expanded Antiretroviral Treatment and Screening for active TB) will measure the impact of a combined TB and HIV intervention – of population level active case-finding for TB, combined with universal testing and treatment for HIV -- on TB incidence, prevalence and incidence of infection when delivered to the entire population of 14 urban, high-prevalence communities in South Africa and Zambia.
The effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage: an international, randomised, double-blind, placebo-controlled trial.
UK Public Health Rapid Support Team (UK-PHRST)
A specialist team ready to respond to disease outbreaks around the world before they develop into health emergencies. The team also conducts rigorous operational research to improve epidemic preparedness.
Use of the cytoskeleton to control Shigella infection
We use Shigella infection to discover new roles for the cytoskeleton in host defence, and use zebrafish to study the cell biology of infection in vivo.
Using dogs to detect COVID-19
Investigating whether dogs can be trained to identify unique odours associated with coronavirus infection
Utoto Salaama/Peaceful Childhood
Understanding and preventing sexual and other forms of violence against children in Zanzibar.
Our overall aim is to support decision-making about the choice or modification of vaccination schedules at international, regional and country levels.
The WOMAN trial, coordinated by the London School of Hygiene & Tropical Medicine (LSHTM) Clinical Trials Unit (CTU) is an international clinical trial of the effect of tranexamic acid on death, hysterectomy and other maternal outcomes, in women with PPH.14.
World AsthmaPhenotypes Study (WASP)
The World AsthmaPhenotypes Study (WASP) aims to better understand and characterise different sub-types (phenotypes) of asthma.
ZikaPLAN (Preparedness Latin America Network) at LSHTM
A multinational and multidisciplinary consortium implementing critical research on the existing Zika virus outbreak whilst preparing a sustainable response capacity for future emerging epidemics in Latin America.