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Dr Andrea Zelmer

Assistant Professor

Room
Room 480

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
+44 (0)207 958 8269

After obtaining a degree in Biology at the Technical University of Braunschweig, Germany I did my PhD at the Helmholtz Centre for Infection Research in Braunschweig where I worked on "Intracellular Bacteria as Vectors for Gene Transfer in vitro and in vivo".

In a previous project as a postdoctoral researcher I focussed on E. coli K1 infection in neonates and treatment thereof in keeping with the theme of bacterial infections.

I joined the School in June 2008 to set up an in vivo imaging system to facilitate testing of anti-Tuberculosis drugs and am currently working on the development of mycobacterial growth inhibition assays (MGIA) to test new TB vaccines. 

Affiliations

Faculty of Infectious and Tropical Diseases
Immunology and Infection Department

Centres

Tuberculosis (TB) Centre

Teaching

Distance learning tutor Infectious Diseases/ Principles of Biology

Research

Research Area
Bacteria
Innate immunity
Vaccines
Immunisation
Discipline
Immunology
Microbiology
Disease and Health Conditions
Infectious disease
Tuberculosis

Selected Publications

Deletion of zmp1 improves Mycobacterium bovis BCG-mediated protection in a guinea pig model of tuberculosis.
Sander, P. ; Clark, S. ; Petrera, A. ; Vilaplana, C. ; Meuli, M. ; Selchow, P. ; Zelmer, A. ; Mohanan, D. ; Andreu, N. ; Rayner, E. ; Dal Molin, M. ; Bancroft, G.J. ; Johansen, P. ; Cardona, P.J. ; Williams, A. ; Böttger, E.C. ;
Vaccine
Increased protective efficacy of recombinant BCG strains expressing virulence-neutral proteins of the ESX-1 secretion system.
Bottai, D. ; Frigui, W. ; Clark, S. ; Rayner, E. ; Zelmer, A. ; Andreu, N. ; de Jonge, M.I. ; Bancroft, G.J. ; Williams, A. ; Brodin, P. ; Brosch, R. ;
Vaccine
Rapid in vivo assessment of drug efficacy against Mycobacterium tuberculosis using an improved firefly luciferase.
Andreu, N.; Zelmer, A.; Sampson, S.L.; Ikeh, M.; Bancroft, G.J.; Schaible, U.E.; Wiles, S.; Robertson, B.D.;
J Antimicrob Chemother
A new in vivo model to test anti-tuberculosis drugs using fluorescence imaging.
Zelmer, A. ; Carroll, P. ; Andreu, N. ; Hagens, K. ; Mahlo, J. ; Redinger, N. ; Robertson, B.D. ; Wiles, S. ; Ward, T.H. ; Parish, T. ; Ripoll, J. ; Bancroft, G.J. ; Schaible, U.E. ;
J Antimicrob Chemother
Noninvasive biophotonic imaging for studies of infectious disease.
Andreu, N.; Zelmer, A.; Wiles, S.;
FEMS Microbiol Rev
Administration of Capsule-Selective Endosialidase E Minimises Up-Regulation of Organ Gene Expression Induced by Experimental Systemic Infection with Escherichia coli K1.
Zelmer, A.; Martin, M.J.; Gundogdu, O.; Birchenough, G.; Lever, R.; Wren, B.W.; Luzio, J.P.; Taylor, P.W.;
Microbiology
Optimisation of bioluminescent reporters for use with mycobacteria.
Andreu, N.; Zelmer, A.; Fletcher, T.; Elkington, P.T.; Ward, T.H.; Ripoll, J.; Parish, T.; Bancroft, G.J.; Schaible, U.; Robertson, B.D.; Wiles, S.;
PLoS One
See all Dr Andrea Zelmer's Publications