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Dr Laith Yakob

BSc MSc DPhil

Associate Professor

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
+44(0)207 927 2684

I am particularly interested in the epidemiology of infectious diseases and in novel technologies for their control. Main research themes include the relationships between climate and disease ecology, cutting-edge methods for combatting diseases (vaccines, integrated control strategy) and disease vectors (systemic insecticides, Wolbachia and genetic control). My research centres at the confluence of the lab, the field and computational modelling.

Affiliations

Faculty of Infectious and Tropical Diseases
Department of Disease Control

Centres

Malaria Centre
Centre for the Mathematical Modelling of Infectious Diseases (CMMID)
Antimicrobial Resistance Centre (AMR)

Teaching

I am on the Senate Postgraduate Taught Committee.  I am the Exam Board Chair for Medical Parasitology and Medical Entomology for Disease control.  I am the module organiser for Parasitology and Entomology (3122) supermodule, and module co-organiser for the Medical Parasitology & Medical Entomology 1-week field trip (3133).  I teach on Parasitology and Entomology (3122) supermodule; Vector Sampling, Identification & Incrimination (3141); Vector-Parasite Interactions (3166); Modelling & the Dynamics of Infectious Diseases (2464); Integrated Vector Management (3176).  I am a short course instructor for 'Introduction to Infectious Disease Modelling and Its Applications', and, 'Antimicrobial Resistance (AMR): a Multidisciplinary Approach'

Research

I am one of the founding eight core members of the UK Public Health Rapid Support Team, who support countries responding to and controlling disease outbreaks before they can develop into a global threat. I am also a founding member of the Antimicrobial Resistance Centre at LSHTM, where I previously acted as the disciplinary head for Epidemiology and Modelling.

 

ACTIVE RESEARCH PROJECTS:

2021-2023
Cost-effectiveness of a Clostridium difficile vaccine in the UK
Pfizer Inc. project grant

2021-2022
Developing target characteristics for mosquito suppression and replacement programmes using modelling
Bill & Melinda Gates Foundation grant

2019-2021
Modelling the impact of a transmission blocking vaccine against leishmaniasis on sand fly vectorial capacity
VALIDATE Network grant

 

 

Research Area
Climate change
Complex interventions
Decision analysis
Helminths
Insects
Parasites
Systematic reviews
Disease control
Global Health
Outbreaks
Protozoa
Vector control
Modelling
Discipline
Epidemiology
Mathematical modelling
Parasitology
Vector biology
Entomology
Disease and Health Conditions
Diarrhoeal diseases
Infectious disease
Malaria
Pandemic diseases
African trypanosomiasis
Dengue
Emerging Infectious Disease
Hospital acquired infection
Influenza
Neglected Tropical Diseases (NTDs)
Respiratory disease
Schistosomiasis
Tropical diseases
Vector borne disease
Zoonotic disease

Selected Publications

β-lactam resistant Streptococcus pneumoniae dynamics following treatment: a dose-response meta-analysis.
Griskaitis M; Furuya-Kanamori L; Allel K; Stabler R; Harris P; Paterson DL; Yakob L
2022
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
The importance of saturating density dependence for population-level predictions of SARS-CoV-2 resurgence compared with density-independent or linearly density-dependent models, England, 23 March to 31 July 2020.
Nightingale ES; Brady OJ; CMMID Covid-19 working group; Yakob L
2021
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
Repurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis.
Sterkel M; Haines LR; Casas-Sánchez A; Owino Adung'a V; Vionette-Amaral RJ; Quek S; Rose C; Silva Dos Santos M; García Escude N; Ismail HM
2021
PLoS biology
The cost-effectiveness of controlling dengue in Indonesia using wMel Wolbachia released at scale: a modelling study.
Brady OJ; Kharisma DD; Wilastonegoro NN; O'Reilly KM; Hendrickx E; Bastos LS; Yakob L; Shepard DS
2020
BMC medicine
Glycan–glycan interactions determine <i>Leishmania</i> attachment to the midgut of permissive sand fly vectors
Hall AR; Blakeman JT; Eissa AM; Chapman P; Morales-García AL; Stennett L; Martin O; Giraud E; Dockrell DH; Cameron NR
2020
CHEMICAL SCIENCE
Evidence of extrinsic factors dominating intrinsic blood host preferences of major African malaria vectors.
Orsborne J; Mohammed AR; Jeffries CL; Kristan M; Afrane YA; Walker T; Yakob L
2020
Scientific Reports
Optimising systemic insecticide use to improve malaria control.
Meredith HR; Furuya-Kanamori L; Yakob L
2019
BMJ Global Health
Projecting the end of the Zika virus epidemic in Latin America: a modelling analysis.
O'Reilly KM; Lowe R; Edmunds WJ; Mayaud P; Kucharski A; Eggo RM; Funk S; Bhatia D; Khan K; Kraemer MUG
2018
BMC medicine
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