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Dr Laith Yakob

BSc MSc DPhil

Associate Professor

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
+44(0)207 927 2684

I am an epidemiologist developing strategies for mitigating resistance in infectious disease control. There are two main themes in which I contribute research: modernized integrated management of insecticide-resistant disease vectors, and, improved methods of surveillance and control of antimicrobial resistance. Although these systems are distinct, there is considerable homology in the mechanisms by which resistance spreads and is managed. I use different kinds of statistical and mathematical modelling to address these themes.

Affiliations

Department of Disease Control
Faculty of Infectious and Tropical Diseases

Centres

Malaria Centre
Centre for the Mathematical Modelling of Infectious Diseases (CMMID)
Antimicrobial Resistance Centre (AMR)

Teaching

I am the Taught Programme co-Director for ITD. I teach on Parasitology and Entomology (3122) supermodule; the Medical Parasitology & Medical Entomology 1-week field trip (3133); Vector Sampling, Identification & Incrimination (3141); Vector-Parasite Interactions (3166); Modelling & the Dynamics of Infectious Diseases (2464); Integrated Vector Management (3176).  I am a short course instructor for 'Introduction to Infectious Disease Modelling and Its Applications', and, 'Antimicrobial Resistance (AMR): a Multidisciplinary Approach'

Research

ACTIVE RESEARCH PROJECTS:

2023-2027
Malaria vector biocontrol using Wolbachia
Private philanthropist funded

2023-2024
The role of Aedes albopictus in dengue transmission
Merck Sharp & Dohme project grant

2021-2024
Cost-effectiveness of a Clostridium difficile vaccine in the UK
Pfizer Inc. project grant

2021-2023
Developing target characteristics for mosquito suppression and replacement programmes using modelling
Bill & Melinda Gates Foundation grant

 

 

Research Area
Climate change
Complex interventions
Decision analysis
Helminths
Insects
Parasites
Systematic reviews
Disease control
Global Health
Outbreaks
Protozoa
Vector control
Modelling
Discipline
Epidemiology
Mathematical modelling
Parasitology
Vector biology
Entomology
Disease and Health Conditions
Diarrhoeal diseases
Infectious disease
Malaria
Pandemic diseases
African trypanosomiasis
Dengue
Emerging Infectious Disease
Hospital acquired infection
Influenza
Neglected Tropical Diseases (NTDs)
Respiratory disease
Schistosomiasis
Tropical diseases
Vector borne disease
Zoonotic disease

Selected Publications

Global antimicrobial-resistance drivers: an ecological country-level study at the human-animal interface.
Allel K; Day L; Hamilton A; Lin L; Furuya-Kanamori L; Moore CE; Van Boeckel T; Laxminarayan R; Yakob L
2023
The Lancet. Planetary health
β-Lactam-Resistant Streptococcus pneumoniae Dynamics Following Treatment: A Dose-Response Meta-analysis.
Griskaitis M; Furuya-Kanamori L; Allel K; Stabler R; Harris P; Paterson DL; Yakob L
2022
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
The importance of saturating density dependence for population-level predictions of SARS-CoV-2 resurgence compared with density-independent or linearly density-dependent models, England, 23 March to 31 July 2020.
Nightingale ES; Brady OJ; CMMID Covid-19 working group; Yakob L
2021
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
Repurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis.
Sterkel M; Haines LR; Casas-Sánchez A; Owino Adung'a V; Vionette-Amaral RJ; Quek S; Rose C; Silva Dos Santos M; García Escude N; Ismail HM
2021
PLoS biology
The cost-effectiveness of controlling dengue in Indonesia using wMel Wolbachia released at scale: a modelling study.
Brady OJ; Kharisma DD; Wilastonegoro NN; O'Reilly KM; Hendrickx E; Bastos LS; Yakob L; Shepard DS
2020
BMC medicine
Glycan–glycan interactions determine <i>Leishmania</i> attachment to the midgut of permissive sand fly vectors
Hall AR; Blakeman JT; Eissa AM; Chapman P; Morales-García AL; Stennett L; Martin O; Giraud E; Dockrell DH; Cameron NR
2020
CHEMICAL SCIENCE
Evidence of extrinsic factors dominating intrinsic blood host preferences of major African malaria vectors.
Orsborne J; Mohammed AR; Jeffries CL; Kristan M; Afrane YA; Walker T; Yakob L
2020
Scientific Reports
Optimising systemic insecticide use to improve malaria control.
Meredith HR; Furuya-Kanamori L; Yakob L
2019
BMJ Global Health
Projecting the end of the Zika virus epidemic in Latin America: a modelling analysis.
O'Reilly KM; Lowe R; Edmunds WJ; Mayaud P; Kucharski A; Eggo RM; Funk S; Bhatia D; Khan K; Kraemer MUG
2018
BMC medicine
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