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Dr Laith Yakob

BSc MSc DPhil

Associate Professor

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
+44(0)207 927 2684

I am an ecologist with particular interest in the role of migration on vector populations and on infectious disease dynamics. In terms of human movement, excellent data exist for informing connectivity between many populations and these can be capitalised upon to inform epidemiology. For example, we recently showed that the Zika epidemic likely spread across Latin/Central America following the road networks, not through air travel as previously believed. For zoonoses, migration data quality is more variable (generally better for livestock than wild animals) introducing greater uncertainty in the role of movement in disease transmission. For example, we showed that the potential for an outbreak of zoonotic knowlesi malaria in southeast Asia is critically dependent on how often macaque hosts enter human villages – a behaviour for which data are scant but burgeoning thanks to macaque-tracking drones. At the bottom of the spectrum, is knowledge of vector dispersal. Tracking vector movement is so difficult that many fundamental questions about them remain: How far does a mosquito fly? How big is a mosquito population? How influential is vector dispersal in infection spread? Questions like these drive much of my research focus.

Affiliations

Department of Disease Control
Faculty of Infectious and Tropical Diseases

Centres

Malaria Centre
Mathematical Modelling of Infectious Diseases
Antimicrobial Resistance Centre

Teaching

I am Deputy Course Director for the MSc in Medical Parasitology and in Medical Entomology for Disease Control (MEDiC). 

Research

I am one of the founding eight core members of the UK Public Health Rapid Support Team, who support countries responding to and controlling disease outbreaks before they can develop into a global threat. I am also a founding member of the Antimicrobial Resistance Centre at LSHTM, where I act as the disciplinary head for Epidemiology and Modelling.

 

ACTIVE RESEARCH PROJECTS:

2018-2021
Early warning systems for dengue outbreaks in SE Asia and Australia
NHMRC (PI Wenbiao Hu; Co-Is: Yakob, Devine, Tu).

2017-2019
New vectors, new diseases: the risk of chikungunya transmission in Australia
NHMRC (PI Francesca Frentiu; Co-Is: Hu, Devine, Yakob, McGraw). 

2017-2021
ZIKAPLAN: Zika Preparedness Latin American Network
ERC-funded Consortium (PI Annelise Wilder-Smith; large network of Co-Is including Yakob).

2016-2020
Mosquito biting behaviour and arboviral transmission: interactions between intrinsic host preferences and local environmental conditions
MRC (PI Yakob; Co-I Walker).

2016-18
ZIKA: surveillance, risk factors and vector management in Brazil
MRC/Newton/Wellcome Trust (PI Yakob; Co-Is: Brasil, Cameron, Edmunds, Funk, Lines, Logan, Rodrigues, Rowland, Walker).

 

Research Area
Climate change
Complex interventions
Decision analysis
Helminths
Insects
Parasites
Systematic reviews
Disease control
Global Health
Outbreaks
Protozoa
Vector control
Modelling
Discipline
Epidemiology
Mathematical modelling
Parasitology
Vector biology
Entomology
Disease and Health Conditions
Diarrhoeal diseases
Infectious disease
Malaria
Pandemic diseases
African trypanosomiasis
Dengue
Emerging Infectious Disease
Hospital acquired infection
Influenza
Neglected Tropical Diseases (NTDs)
Respiratory disease
Schistosomiasis
Tropical diseases
Vector borne disease
Zoonotic disease

Selected Publications

Economic evaluation of interventions designed to reduce Clostridium difficile infection.
Brain D; Yakob L; Barnett A; Riley T; Clements A; Halton K; Graves N
2018
PloS one
Variation in natural exposure to anopheles mosquitoes and its effects on malaria transmission.
Guelbéogo WM; Gonçalves BP; Grignard L; Bradley J; Serme SS; Hellewell J; Lanke K; Zongo S; Sepúlveda N; Soulama I
2018
eLife
Projecting the end of the Zika virus epidemic in Latin America: a modelling analysis.
O'Reilly KM; Lowe R; Edmunds WJ; Mayaud P; Kucharski A; Eggo RM; Funk S; Bhatia D; Khan K; Kraemer MUG
2018
BMC medicine
Heterogeneous and Dynamic Prevalence of Asymptomatic Influenza Virus Infections.
Furuya-Kanamori L; Yakob L
2018
Emerging infectious diseases
Spatiotemporal patterns and climatic drivers of severe dengue in Thailand
Xu Z; Bambrick H; Yakob L; Devine G; Lu J; Frentiu FD; Yang W; Williams G; Hu W
2018
Science of The Total Environment
Using the human blood index to investigate host biting plasticity: a systematic review and meta-regression of the three major African malaria vectors.
Orsborne J; Furuya-Kanamori L; Jeffries CL; Kristan M; Mohammed AR; Afrane YA; O'Reilly K; Massad E; Drakeley C; Walker T
2018
Malaria journal
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