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Dr Catherine Wedderburn

BA MBChB MSc DTM&H MRCPCH

Research Fellow
Wellcome Trust Clinical PhD Fellow in Global Child Health

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

I am a Wellcome Trust Clinical Research Fellow at the London School of Hygiene & Tropical Medicine (LSHTM) with an interest in Paediatrics, HIV and Neuroscience. I am conducting my PhD in South Africa examining the effects of HIV and antiretroviral therapy exposure in uninfected children born to HIV-infected mothers. My research aims to understand the impact of in utero and early life exposures on long-term health outcomes.

I have a Masters in Tropical Medicine and International Health and a Diploma in Tropical Medicine & Hygiene from LSHTM and work in the UK and South Africa. Prior to my PhD I worked on a joint project with LSHTM and the WHO on the dual elimination of mother-to-child transmission of HIV and syphilis initiative and developed an online dashboard to monitor progress towards this goal. While at the International Diagnosics Centre, LSHTM, I was the co-ordinator of the Early Infant Diagnosis of HIV (EID) Consortium (http://eidconsortium.org) which brings together principal investigators and partners working in the field of early infant diagnosis and point-of-care. More recently I have also worked for Médecins Sans Frontières in Khayelitsha, Western Cape, South Africa in the field of maternal and paediatric HIV.

Affiliations

Department of Clinical Research
Faculty of Infectious and Tropical Diseases

Centres

Centre for Maternal Adolescent Reproductive & Child Health (MARCH)

Teaching

I am supervising MSc students in Public Health and Epidemiology.

Research

I am doing my PhD on the ‘Neurodevelopmental effects of HIV and ART exposure: a prospective neuroimaging study of uninfected children born to HIV-infected mothers’ in South Africa funded by a Wellcome Trust Research Training Fellowship. My research involves magnetic resonance imaging of young children and measuring their clinical neurodevelopment with the aim to understand the effects of in utero exposure to HIV and antiretroviral treatment in order to improve global child health. I was awarded the Johnstone & Florence Stoney Studentship from the British Federation of Women Graduates for the research.

Research Area
Child health
Clinical care
Diagnostics
Health promotion
Maternal health
Viruses
Global Health
Medicines
Discipline
Immunoepidemiology
Epidemiology
Medicine
Virology
Disease and Health Conditions
HIV/AIDS
Meningitis
Neurological disease
Disability
Syphilis
Country
United Kingdom
South Africa
Region
Sub-Saharan Africa (all income levels)

Selected Publications

Serology testing in the COVID-19 pandemic response.
Peeling RW; Wedderburn CJ; Garcia PJ; Boeras D; Fongwen N; Nkengasong J; Sall A; Tanuri A; Heymann DL
2020
The Lancet. Infectious diseases
Neuroimaging young children and associations with neurocognitive development in a South African birth cohort study.
Wedderburn CJ; Subramoney S; Yeung S; Fouche J-P; Joshi SH; Narr KL; Rehman AM; Roos A; Ipser J; Robertson FC
2020
NeuroImage
Risk and protective factors for child development: An observational South African birth cohort.
Donald KA; Wedderburn CJ; Barnett W; Nhapi RT; Rehman AM; Stadler JAM; Hoffman N; Koen N; Zar HJ; Stein DJ
2019
PLOS Medicine
The impact of health programmes to prevent vertical transmission of HIV. Advances, emerging health challenges and research priorities for children exposed to or living with HIV: Perspectives from South Africa.
Goga A; Slogrove A; Wedderburn CJ; Feucht U; Wessels J; Ramokolo V; Bhana A; Du Plessis N; Green RJ; Pillay Y
2019
South African Medical Journal
Impact of HIV and antiretroviral drug exposure on lung growth and function over 2 years in an African Birth Cohort.
Gray DM; Wedderburn CJ; MacGinty RP; McMillan L; Jacobs C; Stadler JAM; Hall GL; Zar HJ
2019
AIDS (London, England)
Growth and Neurodevelopment of HIV-Exposed Uninfected Children: a Conceptual Framework.
Wedderburn CJ; Evans C; Yeung S; Gibb DM; Donald KA; Prendergast AJ
2019
Current HIV/AIDS Reports
Neurodevelopment of HIV-exposed uninfected children in South Africa: outcomes from an observational birth cohort study.
Wedderburn CJ; Yeung S; Rehman AM; Stadler JAM; Nhapi RT; Barnett W; Myer L; Gibb DM; Zar HJ; Stein DJ
2019
The Lancet Child & Adolescent Health
Drakenstein Child Health Study (DCHS): investigating determinants of early child development and cognition.
Donald KA; Hoogenhout M; du Plooy CP; Wedderburn CJ; Nhapi RT; Barnett W; Hoffman N; Malcolm-Smith S; Zar HJ; Stein DJ
2018
BMJ paediatrics open
Thyroid Function in Pregnant Women With Moderate to Severe Alcohol Consumption Is Related to Infant Developmental Outcomes.
Donald KA; Wedderburn CJ; Barnett W; Hoffman N; Zar HJ; Redei EE; Stein DJ
2018
FRONTIERS IN ENDOCRINOLOGY
The last and first frontier--emerging challenges for HIV treatment and prevention in the first week of life with emphasis on premature and low birth weight infants.
Cotton MF; Holgate S; Nelson A; Rabie H; Wedderburn C; Mirochnick M
2015
Journal of the International AIDS Society
Using electronic readers to monitor progress toward elimination of mother-to-child transmission of HIV and syphilis: An opinion piece.
Wedderburn CJ; Murtagh M; Toskin I; Peeling RW
2015
International journal of gynaecology and obstetrics
Airways obstruction and pulmonary capillary blood volume in children with sickle cell disease.
Wedderburn CJ; Rees D; Height S; Dick M; Rafferty GF; Lunt A; Greenough A
2014
Pediatric pulmonology
Airways obstruction and pulmonary capillary blood volume in children with sickle cell disease.
Wedderburn CJ; Rees D; Height S; Dick M; Rafferty GF; Lunt A; Greenough A
2013
Pediatric pulmonology
Respiratory support practices in infants born at term in the United Kingdom.
Chowdhury O; Wedderburn CJ; Lee S; Hannam S; Greenough A
2012
European Journal of Pediatrics
Economic evaluation of diagnosing and excluding ectopic pregnancy.
Wedderburn CJ; Warner P; Graham B; Duncan WC; Critchley HOD; Horne AW
2009
Human reproduction (Oxford, England)
The Cambridge Behavioural Inventory revised.
Wear HJ; Wedderburn CJ; Mioshi E; Williams-Gray CH; Mason SL; Barker RA; Hodges JR
2008
Dementia & neuropsychologia
The utility of the Cambridge Behavioural Inventory in neurodegenerative disease.
Wedderburn C; Wear H; Brown J; Mason SJ; Barker RA; Hodges J; Williams-Gray C
2008
Journal of neurology, neurosurgery, and psychiatry
Outcome after interventional or conservative management of unruptured brain arteriovenous malformations: a prospective, population-based cohort study.
Wedderburn CJ; van Beijnum J; Bhattacharya JJ; Counsell CE; Papanastassiou V; Ritchie V; Roberts RC; Sellar RJ; Warlow CP; Al-Shahi Salman R
2008
The Lancet. Neurology
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