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Dr Sam Wassmer

Ph.D.

Associate Professor
in Malaria Pathogenesis

Room
236a

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
+44 (0) 20 7612 7888

Following the completion of his Ph.D. in Marseille, Sam Wassmer joined the Liverpool School of Tropical Medicine in 2005, as a post-doctoral fellow. He was based at the Malawi-Liverpool-Wellcome Trust Clinical Research Programme in Blantyre, and was awarded a Wellcome Trust Research Training Fellowship in 2007 to investigate the influence of endothelial responsiveness to TNF on malaria severity and outcome. In parallel, he contributed to seminal work on the pivotal role of endothelial protein C receptor in fatal paediatric cerebral malaria, associating for the first time coagulation and inflammation with parasite sequestration in the brain.

In September 2010, Sam Wassmer was appointed Assistant Professor in the Department of Microbiology at the New York University School of Medicine, where he worked for over 5 years. During this time, he developed several research projects in Rourkela, India, as part of an NIH-funded International Center of Excellence for Malaria Research. His research focuses on the mechanisms underlying the pathological differences in cerebral malaria between African and Southeast Asian populations, the main affected groups. 

Sam Wassmer joined the School in May 2016 as an Associate Professor in Malaria Pathogenesis.

Affiliations

Department of Infection Biology
Faculty of Infectious and Tropical Diseases

Centres

Malaria Centre

Teaching

Sam has successfully completed the Postgraduate Certificate in Learning and Teaching  at the LSHTM and has become an Associate Fellow of the Higher Education Academy (HEA). He has a wide range of teaching activities, which include:

  • malaria blood stages & immunology (Immunology of Parasitic Infection MSc, M3177),
  • malaria pathophysiology (Infectious Diseases by Distance Learning IDM103, IDM213, IDM503)
  • immunopathology of infectious diseases & malaria pathogenesis (Immunology of Infectious Diseases MSc, M3120)
  • MSc exam marking

He is also tutoring for the Immunology of Infectious Diseases MSc and the Medical Parasitology MSc.

Research

Sam Wassmer's team investigates factors that lead to the development of cerebral malaria in patients infected with Plasmodium falciparum. This includes specific virulence factors of the parasite, as well as host-related determinants across cohorts from different age groups and geographic origins. Sam is also interested in the development of cost-effective and easily deployable diagnostic tools, specifically designed for malaria-endemic settings. 

Research Area
Drug discovery and development
Innate immunity
Parasites
Public health
Protozoa
Discipline
Genomics
Immunoepidemiology
Immunopathology
Cell biology
Medicine
Molecular biology
Parasitology
Pathology
Education
Disease and Health Conditions
Infectious disease
Malaria
Neurological disease
Country
Gabon
India
Malawi
Region
South Asia
Sub-Saharan Africa (all income levels)

Selected Publications

CD8+ T cells and human cerebral malaria: a shifting episteme.
Rénia L; Grau GE; Wassmer SC
2020
The Journal of clinical investigation
Plasmodium vivax in Hematopoietic Niches: Hidden and Dangerous.
Silva-Filho JL; Lacerda MVG; Recker M; Wassmer SC; Marti M; Costa FTM
2020
Trends in parasitology
Malaria inflammation by xanthine oxidase-produced reactive oxygen species.
Ty MC; Zuniga M; Götz A; Kayal S; Sahu PK; Mohanty A; Mohanty S; Wassmer SC; Rodriguez A
2019
EMBO Molecular Medicine
The burden of submicroscopic and asymptomatic malaria in India revealed from epidemiology studies at three varied transmission sites in India.
van Eijk AM; Sutton PL; Ramanathapuram L; Sullivan SA; Kanagaraj D; Priya GSL; Ravishankaran S; Asokan A; Sangeetha V; Rao PN
2019
Scientific reports
New Syndromes Identified by Neuroimaging during Cerebral Malaria.
Hoffmann A; Wassmer SC
2018
The American journal of tropical medicine and hygiene
Magnetic Resonance Imaging of Cerebral Malaria Patients Reveals Distinct Pathogenetic Processes in Different Parts of the Brain.
Mohanty S; Benjamin LA; Majhi M; Panda P; Kampondeni S; Sahu PK; Mohanty A; Mahanta KC; Pattnaik R; Mohanty RR
2017
mSphere
Type I Interferon in Malaria: A Balancing Act.
Mooney JP; Wassmer SC; Hafalla JC
2017
Trends in parasitology
THE EPIDEMIOLOGY OF GENDER DIFFERENCES IN MALARIA UNRELATED TO PREGNANCY
van Eijk AM; Choubey S; Sutton PL; Kanagaraj D; Ramanathapuram L; Patel A; Rao P; Sullivan SA; Wassmer SC; Singh R
2017
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
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