Professor Sarah Staedke


of Malaria & Global Health

Keppel Street
United Kingdom

I am a clinical epidemiologist with specialist training in infectious disease and global public health. I have conducted research on malaria since 1999, and am currently based in Uganda with the Infectious Diseases Research Collaboration.




Faculty of Infectious and Tropical Diseases
Department of Clinical Research


Malaria Centre
Maternal, Adolescent, Reproductive & Child Health (MARCH)
Antimicrobial Resistance Centre


I supervise Masters’ students and PhD candidates from LSHTM, Makerere University, and other institutions.  I also act as a tutor and Deputy Module Organiser for LSHTM’s Distance Learning Malaria module, and serve on the exam board for the East African Diploma in Tropical Medicine & Hygiene and MSc in Tropical Medicine & International Health.



My research is focused on P. falciparum malaria, including the efficacy and safety of antimalarial drugs, methods to improve quality of care and fever case management, surveillance of malaria-related morbidity and mortality, and novel approaches to prevent and control malaria. 

I am particularly interested in intermittent preventive treatment (IPT) of malaria in schoolchildren and the role of chemoprevention in malaria control. We recently completed the START-IPT trial (School-based treatment with ACT to reduce transmission of malaria) in Jinja, Uganda. This cluster-randomised trial assessed the impact of IPT for malaria in schoolchildren with dihydroartemisinin-piperaquine (DP) on population-level outcomes and malaria transmission in Uganda.

My current research projects include:

Uganda PBO Net Study: Impact of long-lasting insecticide treated bednets (LLINs) with and without piperonyl butoxide (PBO) on malaria indicators in Uganda; funded by the Against Malaria Foundation (Dec 2016 to Dec 2018). This cluster-randomised trial aims to evaluate the impact of LLINs distributed in a national campaign in 48 districts in Uganda.

Program for Resistance, Immunology, Surveillance and Modelling of Malaria in Uganda (PRISM2), funded by the US National Institutes of Health (July 2017 to June 2024). A cohort study of community residents living in Tororo, Uganda will provide the framework for research on the epidemiology and transmission of malaria, and parasite and insecticide resistance.

Anti-Microbials In Society: A Global Interdisciplinary Research Hub (AMIS Hub); funded by the UK’s Economic and Social Research Council (May 2017 to April 2021). This qualitative project will investigate use of antimicrobials (anti-malarial drugs and antibiotics) including how drugs are used in human health care, agriculture, farming, and factories.


Research Area
Child health
Clinical trials
Complex interventions
Drug resistance
Health services research
Disease control
Qualitative methods
Randomised controlled trials
Disease and Health Conditions
Infectious disease
Sub-Saharan Africa (developing only)

Selected Publications

Assessment of community-level effects of intermittent preventive treatment for malaria in schoolchildren in Jinja, Uganda (START-IPT trial): a cluster-randomised trial.
Staedke SG; Maiteki-Sebuguzi C; Rehman AM; Kigozi SP; Gonahasa S; Okiring J; Lindsay SW; Kamya MR; Chandler CIR; Dorsey G
The Lancet Global health
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