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Dr Nuno Sepulveda

BSs MSc PhD

Assistant Professor
of Biostatistics and Statistical Genetics

Room
280

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
+44 (0)2079272300

He has a PhD on theoretical immunology from University of Oporto. He joined the LSHTM in November 2010 as a member of the data analysis team of the MalariaGen, an international network for Genetic Epidemiology of Malaria. Since 2012 he is part of Chris Drakeley's group (in the Department of Infection and Immunology - ITD).  

Affiliations

Department of Infection Biology
Faculty of Infectious and Tropical Diseases

Centres

Malaria Centre
Mathematical Modelling of Infectious Diseases
Statistical Methodology

Teaching

He has been lecturing in the in-house Analysis and Design of Research Studies course. He has also been teaching statistics and epidemiology overseas, namely, in PhD programmes for biomedical researchers in Portugal and Cape Verde. 

Research

Currently he studies the statistics aspects of using serological data to assess malaria transmission intensity, its putative changes over time, and certification of malaria elimination. He is also involved in projects aiming to understand Malaria and Zika virus epidemiology in Cape Verde.

Research Area
Human genetics
Parasites
Statistical methods
T-cell immunology
Modelling
Discipline
Genetic epidemiology
Genomics
Immunoepidemiology
Epidemiology
Genetics
Mathematics
Mathematical modelling
Statistics
Disease and Health Conditions
Malaria
Tropical diseases
Vector borne disease
Country
Brazil
Cape Verde
Portugal
Region
Latin America & Caribbean (all income levels)
Sub-Saharan Africa (all income levels)

Selected Publications

Global analysis of Plasmodium falciparum histidine-rich protein-2 (pfhrp2) and pfhrp3 gene deletions using whole-genome sequencing data and meta-analysis.
Sepúlveda N; Phelan J; Diez-Benavente E; Campino S; Clark TG; Hopkins H; Sutherland C; Drakeley CJ; Beshir KB
2018
Infection, genetics and evolution
Malaria host candidate genes validated by association with current, recent and historic measures of transmission intensity.
Sepúlveda N; Manjurano A; Campino SG; Lemnge M; Lusingu J; Olomi R; Rockett KA; Hubbart C; Jeffreys A; Rowlands K
2017
The Journal of infectious diseases
African glucose-6-phosphate dehydrogenase alleles associated with protection from severe malaria in heterozygous females in Tanzania.
Manjurano A; Sepulveda N; Nadjm B; Mtove G; Wangai H; Maxwell C; Olomi R; Reyburn H; Riley EM; Drakeley CJ
2015
PLoS genetics
Current Mathematical Models for Analyzing Anti-Malarial Antibody Data with an Eye to Malaria Elimination and Eradication.
Sepúlveda N; Stresman G; White MT; Drakeley CJ
2015
Journal of immunology research
Estimation of T-cell repertoire diversity and clonal size distribution by Poisson abundance models.
Sepúlveda N; Paulino CD; Carneiro J
2010
Journal of immunological methods
Bayesian analysis of allelic penetrance models for complex binary traits
Sepulveda N; Paulino CD; Penha-Goncalves C
2009
Computational statistics & data analysis
Allelic penetrance approach as a tool to model two-locus interaction in complex binary traits.
Sepúlveda N; Paulino CD; Carneiro J; Penha-Gonçalves C
2007
Heredity
See more Publications