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Dr Sophie Rhodes

MMTH MSc PhD

Research Fellow

Room
LG19

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
07725090997

Sophie studied an MMTH in Applied Mathematics at the University of East Anglia, with a focus on mathematical biology. Her final year dissertation focussed on the mathematical modelling of blood flow in the microcirculatory system. Sophie then went on to complete an MSc in Epidemiology from Imperial College, where she directed her experience of mathematical modelling towards disease transmission dynamics and Bayesian parameter inference techniques for stochastic epidemic models.

Affiliations

Faculty of Epidemiology and Population Health
Department of Infectious Disease Epidemiology

Centres

Mathematical Modelling of Infectious Diseases
Tuberculosis (TB) Centre
Vaccine Centre

Research

Sophie has completed her PhD entitled "The development of a mathematical modelling framework to translate TB vaccine responses between species and predict the most immunogenic dose in humans using animal data". The overall purpose of her PhD was to develop a mathematical modelling framework to translate TB vaccine response between species and predict the most immunogenic dose in humans using animal data.

Sophie is now working as a Research Fellow at LSHTM, continuing to develop the mathematical modelling used in her PhD for Malaria, Yellow Fever and Polio vaccines.

Research Area
Bacteria
T-cell immunology
Vaccines
Viruses
Immunisation
Pharmacokinetics
Modelling
Discipline
Immunology
Mathematical modelling
Vaccinology
Disease and Health Conditions
Tuberculosis

Selected Publications

Predicting IFN-γ responses after BCG vaccination in humans from macaques: A proof-of-concept study of Immunostimulation/Immunodynamic modelling methods.
Rhodes, S.J. ; Sarfas, C. ; Knight, G.M. ; White, A. ; Pathan, A.A. ; McShane, H. ; Evans, T.G. ; Fletcher, H. ; Sharpe, S. ; White, R.G. ;
2017
Clin Vaccine Immunol
Individual-level factors associated with variation in mycobacterial-specific immune response: Gender and previous BCG vaccination status.
Rhodes, S.J. ; Knight, G.M. ; Fielding, K. ; Scriba, T.J. ; Pathan, A.A. ; McShane, H. ; Fletcher, H. ; White, R.G. ;
2016
Tuberculosis (Edinb)
The TB vaccine H56+IC31 dose-response curve is peaked not saturating: Data generation for new mathematical modelling methods to inform vaccine dose decisions.
Rhodes, S.J. ; Zelmer, A. ; Knight, G.M. ; Prabowo, S.A. ; Stockdale, L. ; Evans, T.G. ; Lindenstrøm, T. ; White, R.G. ; Fletcher, H. ;
2016
Vaccine
See all Dr Sophie Rhodes's Publications