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Dr Edward Parker

Assistant Professor

London School of Hygiene & Tropical Medicine
Keppel Street
London
WC1E 7HT
United Kingdom

My research explores factors influencing the implementation and effectiveness of vaccines. I am currently the co-lead of Theme 1 (Making the most of real-world data) for the NIHR Health Protection Research Unit in Immunisation at LSHTM. In collaboration with the UK Health Security Agency, our work seeks to harness electronic health record data to improve vaccine coverage and drive evidence-based policy in the UK.

Alongside my work in electronic health records, I am co-director of LSHTM’s Vaccine Centre and hold a position at LSHTM’s Department of Clinical Research, where I run several projects exploring the link between the gut microbiome and oral vaccine response in low-income settings. This includes a project comparing virome development among newborns in the UK and Malawi funded by a UKRI IMPRINT network pump-priming award.

I am interested in the visualisation and communication of data, and led the development of LSHTM’s COVID-19 vaccine tracker from April 2020 to August 2022. In late 2021, I acted as a consultant for the COVID-19 Working Group of the WHO's Strategic Advisory Group of Experts on Immunization.

I am a keen but sporadic science writer. My popular science writing has been published The Guardian, The Independent, Science-based Medicine and The Conversation, and I was shortlisted and highly commended for the 2014 Max Perutz science writing award.

Affiliations

Department of Clinical Research
Faculty of Infectious and Tropical Diseases

Centres

Vaccine Centre

Teaching

I am currently a lecturer on LSHTM’s MSc in Medical Microbiology, a tutor on the Distance Learning Viral Infections module, and a module organiser for the Professional Certificate in Pharmacoepidemiology & Pharmacovigilance.

Research

- Vaccines
- Electronic Health Records
- Microbiome
- Data Science
- Poliovirus
- Rotavirus
Research Area
Bacteria
Child health
Immunisation
Neonatal health
Systematic reviews
Vaccines
Bioinformatics
Epidemiology
Immunology
Molecular biology
Vaccinology
Virology
Disease and Health Conditions
Diarrhoeal diseases
Pandemic diseases
Infectious diseases
Country
Gambia
India
Malawi
Region
South Asia
Sub-Saharan Africa (developing only)

Selected Publications

Identification of patients undergoing chronic kidney replacement therapy in primary and secondary care data: validation study based on OpenSAFELY and UK Renal Registry.
Santhakumaran, S; Fisher, L; Zheng, B; MAHALINGASIVAM, V; Plumb, L; PARKER, EP; Steenkamp, R; Morton, C; Mehrkar, A; Bacon, S; Lyon, S; Konstant-Hambling, R; GOLDACRE, B; MacKenna, B; TOMLINSON, LA; Nitsch, D;
2024
BMJ medicine
Comparative safety and effectiveness of Pfizer BA.4-5 versus Sanofi during the spring 2023 COVID-19 booster vaccination programme in England: a matched cohort study in OpenSAFELY-TPP
Andrews, CD; PRESTIGE, E; PARKER, EP K; Walker, V; Palmer, T; Schaffer, AL; Green, AC A; Curtis, HJ; Walker, A; Smith, RM; Wood, C; Bates, C; Mehrkar, A; MacKenna, B; Bacon, SC J; GOLDACRE, B; Hernán, MA; Sterne, JA C; Hulme, WJ;
2024
Cold Spring Harbor Laboratory
Safe in pregnancy: A global living systematic review and meta-analysis of COVID-19 vaccines in pregnancy.
Buekens, P; Berrueta, M; Ciapponi, A; Bardach, A; Mazzoni, A; Rodriguez-Cairoli, F; Gottlieb, SL; KAMPMANN, B; PARKER, EP K; Xiong, X; Zaraa, S; Stergachis, A;
2024
Vaccine
Increased bacterial taxonomic and functional diversity is associated with impaired rotavirus vaccine immunogenicity in infants from India and Malawi.
Cunningham-Oakes, E; Bronowski, C; Chinyama, E; Jere, KC; Sindhu, KN C; Kang, G; Iturriza-Gómara, M; Darby, AC; PARKER, EP K;
2023
BMC microbiology
Effect of the 2022 COVID-19 booster vaccination campaign in 50 year olds in England: regression discontinuity analysis in OpenSAFELY
Schaffer, A; Hulme, W; Horne, E; PARKER, E; Walker, V; Stables, C; Mehrkar, A; Bacon, SC J; Bates, C; GOLDACRE, B; Walker, A; Hernán, M; Sterne, J; The OpenSAFELY Collaborative,;
2023
medRxiv
CHALLENGES IN ESTIMATING THE EFFECTIVENESS OF 2 DOSES OF COVID-19 VACCINE BEYOND 6 MONTHS IN ENGLAND.
Horne, EM F; Hulme, WJ; KEOGH, RH; Palmer, TM; WILLIAMSON, EJ; PARKER, EP K; Walker, VM; Knight, R; Wei, Y; Taylor, K; Fisher, L; Morley, J; Mehrkar, A; Dillingham, I; Bacon, S; GOLDACRE, B; Sterne, JA C; OpenSAFELY Collaborative, FT;
2023
American journal of epidemiology
Comparative effectiveness of sotrovimab and molnupiravir for preventing severe COVID-19 outcomes in patients on kidney replacement therapy: observational study using the OpenSAFELY-UKRR and SRR databases.
ZHENG, B; Campbell, J; Carr, EJ; Tazare, J; Nab, L; MAHALINGASIVAM, V; Mehrkar, A; Santhakumaran, S; Steenkamp, R; Loud, F; Lyon, S; Scanlon, M; Hulme, WJ; Green, AC A; Curtis, HJ; Fisher, L; PARKER, E; GOLDACRE, B; DOUGLAS, I; Evans, S; MacKenna, B; Bell, S; TOMLINSON, LA; NITSCH, D; OpenSAFELY Collaborative and LH&W NCS (or CONVALES,;
2023
Clinical kidney journal
Bias assessment of a test-negative design study of COVID-19 vaccine effectiveness used in national policymaking.
GRAHAM, S; Tessier, E; Stowe, J; Bernal, JL; PARKER, EP K; NITSCH, D; MILLER, E; Andrews, N; Walker, JL; McDonald, HI;
2023
Nature communications
Ethnic differences in the indirect effects of the COVID-19 pandemic on clinical monitoring and hospitalisations for non-COVID conditions in England: a population-based, observational cohort study using the OpenSAFELY platform.
COSTELLO, RE; Tazare, J; Piehlmaier, D; HERRETT, E; Parker, EP K; ZHENG, B; Mansfield, KE; HENDERSON, AD; CARREIRA, H; BIDULKA, P; WONG, AY S; WARREN-GASH, C; Hayes, JF; Quint, JK; MacKenna, B; Mehrkar, A; EGGO, RM; Katikireddi, SV; Tomlinson, L; LANGAN, SM; Mathur, R; LH&W NCS (or CONVALESCENCE) Collaborative,; OpenSAFELY collaborative,;
2023
EClinicalMedicine
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