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Dr Luis Nacul

MD, PhD

Associate Professor
of epidemiology and public health (clinical)

Room
490

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
02072994814

I have wide experience in public health, epidemiology and in general practice and medicine, having worked at health services and in clinical and public health research in Brazil, before joining the School, where I now work as a part-time Clinical Associate Professor in epidemiology and public health.

My main research interests are in ME/CFS and in chronic diseases and disability more generally. I direct the CureME research group (http://cureme.lshtm.ac.uk/) contributing with my clinical, epidemiological and public health skills to our multi-disciplinary research into ME/CFS, in partnership with experts from 3 Departments at the School and with people with ME/CFS. One of our flagship projects has been the UK ME/CFS Biobank, one of the pioneer biobank facilities in the world for the study of ME/CFS, which functions as an open resource for research in both ME/CFS and MS.   

Other interests include in congenital disorders and zika virus infection, with emphasis on the impact of disability and on interventions aiming at reducing disease incidence and morbidity. My activities in these fields have included leading on the creation of a toolkit for Health Needs Assessment in Congenital Disorders in Low and Middle-Income Countries (http://www.bornhealthy.org/toolkit.html) and participation in the Zika-Alliance consortium (https://zikalliance.tghn.org/).

Affiliations

Faculty of Infectious and Tropical Diseases
Department of Clinical Research

Teaching

My  main teaching has been in epidemiology and public health. I was one of the first course organisers for the Epidemiology MSc by Distant Learning with contribution to various teaching modules. I have supervised a number of post-graduate students in the UK and overseas. 

Research

I am the principal investigator for the National INstitutes of Health (US)-funded study ‘A longitudinal immunological and virological study for ME CFS biomarker discovery’; and for the ME Assocaitionfunded study on "UK ME/CFS Biobank: Opening our Doors") I have previously been the principal investigator for the feasibility studies on establishing a disease-specific post-mortem tissue bank and Biobank for the study of ME/CFS, which helped shape the current NIH-funded project. Previously I had been the London lead for the CFS/ME Observatory project, which encompassed a number of studies on the epidemiology, health services and social aspects of ME/CFS.

Research Area
Child health
Clinical care
Clinical databases
Diagnostics
Human genetics
Primary care
Public health
Health services
Public understanding
Discipline
Epidemiology
Genetics
Medicine
Disease and Health Conditions
Chronic disease
Disability
Chronic Fatigue Syndrome
Country
Argentina
Belgium
Brazil
Germany
Spain
France
United Kingdom
Italy
Latvia
Norway
Portugal
Uruguay
United States
Region
Euro area
European Union
Latin America & Caribbean (all income levels)

Selected Publications

Rethinking the Standard of Care for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.
Friedberg F; Sunnquist M; Nacul L
2019
Journal of general internal medicine
Myalgic encephalomyelitis/chronic fatigue Syndrome (ME/CFS): Investigating care practices pointed out to disparities in diagnosis and treatment across European Union.
Strand EB; Nacul L; Mengshoel AM; Helland IB; Grabowski P; Krumina A; Alegre-Martin J; Efrim-Budisteanu M; Sekulic S; Pheby D
2019
PloS one
Study protocol for the multicentre cohorts of Zika virus infection in pregnant women, infants, and acute clinical cases in Latin America and the Caribbean: the ZIKAlliance consortium.
Avelino-Silva VI; Mayaud P; Tami A; Miranda MC; Rosenberger KD; Alexander N; Nacul L; Segurado A; Pohl M; Bethencourt S
2019
BMC infectious diseases
HERV-K and HERV-W transcriptional activity in myalgic encephalomyelitis/chronic fatigue syndrome
Rodrigues LS; da Silva Nali LH; Leal COD; Sabino EC; Lacerda EM; Kingdon CC; Nacul L; Romano CM
2019
Autoimmunity Highlights
Circulating levels of GDF15 in patients with myalgic encephalomyelitis/chronic fatigue syndrome.
Melvin A; Lacerda E; Dockrell HM; O'Rahilly S; Nacul L
2019
Journal of translational medicine
Cellular immune function in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Cliff JM; King EC; Lee J-S; Sepúlveda N; Wolf A-S; Kingdon C; Bowman E; Dockrell HM; Nacul L; Lacerda E
2019
Frontiers in Immunology
A logistic regression analysis of risk factors in ME/CFS pathogenesis.
Lacerda EM; Geraghty K; Kingdon CC; Palla L; Nacul L
2019
BMC neurology
See more Publications