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Ms Amy Mulick

BSc MA MSc

Research Fellow
in Statistical Epidemiology

Room
249

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

I work as an applied statistician, addressing statistical and epidemiological questions in diverse medical specialties. Special interests are metabolomics, biomarker discovery, linear mixed modelling, statistical programming and complex modelling.

Currently (February 2018) I work with Dr Sinead Langan on the problem of phenotyping eczema. 

Affiliations

Faculty of Epidemiology and Population Health
Department of Medical Statistics

Centres

Statistical Methodology

Teaching

In Term 1 I organise Introduction to Statistical Computing on the London-based MSc in Medical Statistics and teach the Stata module, and I assist practical sessions for Robust Statistical Methods. In Term 3 I lecture on metabolomics during the 'Big Data' session. Throughout the year I tutor on the module ‘Further Statistical Methods for Clinical Trials’ on the distance learning MSc in Clinical Trials.

Previously I organised or assisted with other statistical modules including Probability, Inference, Analytical Techniques, Linear Regression, Statistical Methods in Epidemiology (SME) and Advanced Statistical Methods in Epidemiology (ASME), and have delivered similar content in summer short courses, externally in the UK and abroad.

Research

Currently I am researching and developing optimal statistical methods for identifying phenotypes of disease, with application to eczema (atopic dermatitis).  My ongoing work with Professor JP Casas at UCL is in using metabolomic profiles to quantify heterogeneity in serum high-density lipoprotein (HDL) metabolism and to identify metabolites that can discriminate between different (medical) causes of mortality.

Statistical methods: Survival analysis, linear mixed models, exploratory factor analysis, k-means and hierarchical cluster analysis, latent class analysis, meta-analysis.

Research Area
Statistical methods
Discipline
Epidemiology
Statistics

Selected Publications

Design optimization for clinical trials in early-stage manifest Huntington's disease.
Frost, C. ; Mulick, A. ; Scahill, R.I. ; Owen, G. ; Aylward, E. ; Leavitt, B.R. ; Durr, A. ; Roos, R.A.C. ; Borowsky, B. ; Stout, J.C. ; Reilmann, R. ; Langbehn, D.R. ; Tabrizi, S.J. ; Sampaio, C. ; TRACK-HD Investigators, . ;
2017
Mov Disord
Visuospatial Processing Deficits Linked to Posterior Brain Regions in Premanifest and Early Stage Huntington's Disease.
Labuschagne, I. ; Cassidy, A.M. ; Scahill, R.I. ; Johnson, E.B. ; Rees, E. ; O'Regan, A. ; Queller, S. ; Frost, C. ; Leavitt, B.R. ; Dürr, A. ; Roos, R. ; Owen, G. ; Borowsky, B. ; Tabrizi, S.J. ; Stout, J.C. ; TRACK-HD Investigators, . ;
2016
J Int Neuropsychol Soc
Mendelian Randomisation study of the influence of eGFR on coronary heart disease.
Charoen, P. ; Nitsch, D. ; Engmann, J. ; Shah, T. ; White, J. ; Zabaneh, D. ; Jefferis, B. ; Wannamethee, G. ; Whincup, P. ; Mulick Cassidy, A. ; Gaunt, T. ; Day, I. ; McLachlan, S. ; Price, J. ; Kumari, M. ; Kivimaki, M. ; Brunner, E. ; Langenberg, C. ; Ben-Shlomo, Y. ; Hingorani, A. ; Whittaker, J. ; Pablo Casas, J. ; Dudbridge, F. ; UCLEB Consortium, . ; COLLABORATORS;Dale, C. ; Finan, C. ; Wong, A. ; Ong, K. ; Drenos, F. ; Cooper, J. ; Sofat, R. ; Schmidt, F. ; Lawlor, D.A. ; Talmud, P.J. ; Humphries, S.E. ; Hardy, R. ; Kuh, D. ; Wareham, N. ; Morris, R. ; Plagno, V. ;
2016
Sci Rep
Improved survival in a cohort of trial participants with metastatic castration-resistant prostate cancer demonstrates the need for updated prognostic nomograms.
Omlin, A. ; Pezaro, C. ; Mukherji, D. ; Mulick Cassidy, A. ; Sandhu, S. ; Bianchini, D. ; Olmos, D. ; Ferraldeschi, R. ; Maier, G. ; Thompson, E. ; Parker, C. ; Attard, G. ; de Bono, J. ;
2013
Eur Urol
Sarcopenia and change in body composition following maximal androgen suppression with abiraterone in men with castration-resistant prostate cancer.
Pezaro, C. ; Mukherji, D. ; Tunariu, N. ; Cassidy, A.M. ; Omlin, A. ; Bianchini, D. ; Seed, G. ; Reid, A.H. ; Olmos, D. ; de Bono, J.S. ; Attard, G. ;
2013
Br J Cancer
Clinical and biochemical consequences of CYP17A1 inhibition with abiraterone given with and without exogenous glucocorticoids in castrate men with advanced prostate cancer.
Attard, G. ; Reid, A.H. ; Auchus, R.J. ; Hughes, B.A. ; Cassidy, A.M. ; Thompson, E. ; Oommen, N.B. ; Folkerd, E. ; Dowsett, M. ; Arlt, W. ; de Bono, J.S. ;
2012
J Clin Endocrinol Metab
Multi-purpose utility of circulating plasma DNA testing in patients with advanced cancers.
Perkins, G. ; Yap, T.A. ; Pope, L. ; Cassidy, A.M. ; Dukes, J.P. ; Riisnaes, R. ; Massard, C. ; Cassier, P.A. ; Miranda, S. ; Clark, J. ; Denholm, K.A. ; Thway, K. ; Gonzalez De Castro, D. ; Attard, G. ; Molife, L.R. ; Kaye, S.B. ; Banerji, U. ; de Bono, J.S. ;
2012
PLoS One
Unbiased and automated identification of a circulating tumour cell definition that associates with overall survival.
Ligthart, S.T. ; Coumans, F.A. ; Attard, G. ; Cassidy, A.M. ; de Bono, J.S. ; Terstappen, L.W. ;
2011
PLoS One
See all Ms Amy Mulick's Publications