Dr Daniela Manno
Clinical Assistant Professor
London School of Hygiene & Tropical Medicine
I am a clinical epidemiologist with extensive research experience in infectious diseases and clinical trials. I am one of the investigators of the EBOVAC1 and EBOVAC3 projects, which comprise a set of clinical trials on a two-dose Ad26.ZEBOV, MVA-BN-Filo Ebola vaccine regimen. The findings of these trials provided important data on the safety and immunogenicity of this vaccine regimen and supported its marketing authorisations in the European Union in 2020 for Ebola virus disease (EVD) prophylaxis.
As part of the EBOVAC projects, we also conducted a serosurvey to estimate the prevalence of IgG antibodies to Ebola virus amongst individuals who never experienced symptomatic EVD in a population previously exposed to Ebola and a cohort study to evaluate the effect of malaria infection on the immune response to the Ad26.ZEBOV, MVA-BN-Filo vaccine regimen in adults and children.
I am one of the tutors of the modules 'Applying Public Health Principles in Developing Countries' (3198) and ‘Control of Sexually Transmitted Infections’ (3192).
My main research interests focus on the conduct of clinical trials and other epidemiological studies in the field of infectious diseases and vaccines.