Dr Lola Madrid Castillo

Clin. Assist. Professor in Epidemiology

United Kingdom

I am a paediatrician and epidemiologist with more than 10 years of experience working in resources-constrain settings in South Africa, Mozambique, Ethiopia and Guinea-Bissau among other countries, as a clinician and researcher, especially focused on malaria, HIV, vertical transmission of infectious diseases, epidemiology and new diagnostic tools of bacterial invasive diseases and pneumonia, antimicrobial resistance and child mortality.

For the last five years, I have been working as an overstaff at the London School of Hygiene & Tropical Medicine based in Eastern Ethiopia, leading a new research unit in collaboration with a local University called Haramaya University in a partnership called Hararghe Health Research Partnership. I have been the site director implementing research projects such as Child Health and Mortality Prevention Surveillance (CHAMPS) and other projects in maternal and child health, combining scientific leadership roles with logistic and administrative responsibilities. I am now leading a new research area on micronutrient deficiencies and neural tube defects in Eastern Ethiopia, a condition found as a major cause of stillbirths and child death in CHAMPS-Ethiopia as well as other projects such as invasive bacterial diseases surveillance including prognosis biomarkers.


Department of Infectious Disease Epidemiology and International Health
Faculty of Epidemiology and Population Health


I have been involved in intermittent teachings such as seminars and practical sessions of modules offered at LSHTM, I have been a tutor for the module EPM 307 Global Epidemiology of non-communicable Diseases and have been recently selected as Module Organizer for the same module, role which starts in April 2024. Moreover, I am leading the scientific seminars agenda and workshops for the national staff in Ethiopia working in the partnership between LSHTM and Haramaya University.

I am supervising two Ethiopian PhD students as the first supervisor (2nd and 3rd of PhD, both with approved upgrading) and 1 DrPH student (2nd supervisor) enrolled at LSHTM in the CSRD scheme.


My current areas of research interest are major causes of child mortality and severe illness in low-income countries, including the aetiology of invasive bacterial diseases and associated antimicrobial resistance, prognosis biomarkers among children with severe illness and micronutrient deficiencies and related outcomes among pregnant women and children.
Research Area
AMR (Antimicrobial resistance)
Disease burden
Child health
Neonatal health
Disease and Health Conditions
Infectious diseases
Hospital acquired infection
Children with disabilities
Sub-Saharan Africa (developing only)

Selected Publications

Comparison of causes of stillbirth and child deaths as determined by verbal autopsy and minimally invasive tissue sampling
Assefa, N; Scott, A; Madrid, L; Dheresa, M; Mengesha, G; Mahdi, S; Mahtab, S; Dangor, Z; Myburgh, N; Mothibi, LK; Sow, SO; Kotloff, KL; Tapia, MD; Onwuchekwa, UU; Djiteye, M; Varo, R; Mandomando, I; Nhacolo, A; Sacoor, C; Xerinda, E; Ogbuanu, I; Samura, S; Duduyemi, B; Swaray-Deen, A; Bah, A; ... Whitney, C.
Cold Spring Harbor Laboratory
Burden of child mortality from malaria in high endemic areas: Results from the CHAMPS network using minimally invasive tissue sampling.
Ogbuanu, IU; Otieno, K; Varo, R; Sow, SO; Ojulong, J; Duduyemi, B; Kowuor, D; Cain, CJ; Rogena, EA; Onyango, D; Akelo, V; Tippett Barr, BA; TerKuile, F; Kotloff, KL; Tapia, MD; Keita, AM; Juma, J; Assefa, N; Assegid, N; Acham, Y; Madrid, L; SCOTT, JA G; Arifeen, SE; Gurley, ES; Mahtab, S; ... CHAMPS consortium,
The Journal of infection
Post-mortem investigation of deaths due to pneumonia in children aged 1-59 months in sub-Saharan Africa and South Asia from 2016 to 2022: an observational study.
Mahtab, S; Blau, DM; Madewell, ZJ; Ogbuanu, I; Ojulong, J; Lako, S; Legesse, H; Bangura, JS; Bassat, Q; Mandomando, I; Xerinda, E; Fernandes, F; Varo, R; Sow, SO; Kotloff, KL; Tapia, MD; Keita, AM; Sidibe, D; Onyango, D; Akelo, V; Gethi, D; Verani, JR; Revathi, G; SCOTT, JA G; Assefa, N; ... CHAMPS Consortium,
The Lancet. Child & adolescent health
Child deaths caused by Klebsiella pneumoniae in sub-Saharan Africa and south Asia: a secondary analysis of Child Health and Mortality Prevention Surveillance (CHAMPS) data.
Verani, JR; Blau, DM; Gurley, ES; Akelo, V; Assefa, N; Baillie, V; Bassat, Q; Berhane, M; Bunn, J; Cossa, AC A; El Arifeen, S; Gunturu, R; Hale, M; Igunza, A; Keita, AM; Kenneh, S; Kotloff, KL; Kowuor, D; Mabunda, R; Madewell, ZJ; Madhi, S; Madrid, L; Mahtab, S; Miguel, J; Murila, FV; ... Breiman, RF.
The Lancet. Microbe
Twice-Daily Dosing of Dolutegravir in Infants on Rifampicin Treatment: A Pharmacokinetic Substudy of the EMPIRICAL Trial.
Jacobs, TG; Mumbiro, V; Cassia, U; Zimba, K; Nalwanga, D; Ballesteros, A; Domínguez-Rodríguez, S; Tagarro, A; Madrid, L; Mutata, C; Chitsamatanga, M; Bwakura-Dangarembizi, M; Passanduca, A; Buck, WC; Nduna, B; Chabala, C; Najjingo, E; Musiime, V; Moraleda, C; Colbers, A; Mujuru, HA; Rojo, P; Burger, DM; EMPIRICAL Clinical Trial Group,;
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
First-Line Antituberculosis Drug Concentrations in Infants With HIV and a History of Recent Admission With Severe Pneumonia.
Chabala, C; Jacobs, TG; Moraleda, C; Ndaferankhande, JM; Mumbiro, V; Passanduca, A; Namuziya, N; Nalwanga, D; Musiime, V; Ballesteros, A; Domínguez-Rodríguez, S; Chitsamatanga, M; Cassia, U; Nduna, B; Bramugy, J; Sacarlal, J; Madrid, L; Nathoo, KJ; Colbers, A; Burger, DM; Mulenga, V; Buck, WC; Mujuru, HA; Te Brake, LH M; Rojo, P; ... EMPIRICAL clinical trial group
Journal of the Pediatric Infectious Diseases Society
Provider adherence to clinical care recommendations for infants and children who died in seven low- and middle-income countries in the Child Health and Mortality Prevention Surveillance (CHAMPS) network.
Rees, CA; Igunza, KA; Madewell, ZJ; Akelo, V; Onyango, D; El Arifeen, S; Gurley, ES; Hossain, MZ; Rahman, A; Alam, M; SCOTT, JA G; Assefa, N; Madrid, L; Belachew, A; Leulseged, H; Kotloff, KL; Sow, SO; Tapia, MD; Keita, AM; Sidibe, D; Sitoe, A; Varo, R; Ajanovic, S; Bassat, Q; Mandomando, I; ... Child Health and Mortality Prevention Surveillance,
Mortality associated with third-generation cephalosporin resistance in Enterobacterales bloodstream infections at eight sub-Saharan African hospitals (MBIRA): a prospective cohort study.
Aiken, AM; Rehman, AM; De Kraker, ME A; Madrid, L; Kebede, M; Labi, A-K; Obeng-Nkrumah, N; Nyamwaya, B; Kagucia, E; Cocker, D; Kawaza, K; Lester, R; Iregbu, KC; Medugu, N; Nwajiobi-Princewill, PI; Dramowski, A; Sonda, T; Hemed, A; Fwoloshi, S; Ojok, D; SCOTT, JA G; Whitelaw, A; MBIRA study collaborators,;
The Lancet. Infectious diseases
Stillbirths and Neonatal Deaths Caused by Group B <i>Streptococcus</i> in Africa and South Asia Identified Through Child Health and Mortality Prevention Surveillance (CHAMPS).
Mahtab, S; Madewell, ZJ; Madhi, SA; Wise, A; Swart, PJ; Velaphi, S; Mandomando, I; Bramugy, J; Mabunda, R; Xerinda, E; SCOTT, AG; Assefa, N; Madrid, L; Bweihun, M; Temesgen, F; Onyango, D; Akelo, V; Oliech, R; Otieno, P; Verani, JR; Arifeen, SE; Gurley, ES; Alam, M; Rahman, A; Hossain, MZ; ... CHAMPS Consortium ,
Open forum infectious diseases
See more information