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Prof Grant Mackenzie

Professor

United Kingdom

Dr Mackenzie is a clinical epidemiologist/paediatrician with a research focus to link clinical/field studies with laboratory investigations to answer biological and public health question relevant to infectious disease and child health in low-income settings. He trained clinically in Australia and completed his PhD there before undertaking additional training and experience in HIV care in London and Kenya. He has been based in West Africa at the Basse Field Station of the Medical Research Council Unit The Gambia at LSHTM since 2008.

Affiliations

Department of Disease Control
Faculty of Infectious and Tropical Diseases

Teaching

Dr Mackenzie has led the academic environment at the MRCG at LSHTM Basse Field Station since 2008, leading the regular Journal Club and Scientific Seminars and supporting others to gain experience coordinating these activities. He has supervised two PhD students to completion. He has supervised four Master's students and summer projects for five LSHTM Master's students.

Dr Mackenzie is a member of the team delivering the LSHTM distance learning programme for Control of Communicable Diseases, marking exams and assignments, formulating new questions and supporting students on the Moodle forum. He also lectures in the LSHTM short course on Introductory Epidemiology and Biostatistics held each year in The Gambia.

Research

Dr Mackenzie has co-ordinated surveillance for pneumococcal disease and carriage evaluating the clinical and economic effectiveness of the introduction of pneumococcal conjugate vaccine in The Gambia. He is currently conducting a large cluster-randomised trial of different pneumococcal vaccine schedules.

His other work has investigated long-term outcomes after childhood hospital admissions and the critical role of malnutrition, epidemiology, aetiology and risk factors for childhood pneumonia, the changing performance over time of IMCI criteria for pneumonia, causes of serious bacterial illness and interactions with malaria epidemiology, and the epidemiology of acute respiratory viral disease in children.

Selected Publications

Directly observed social contact patterns among school children in rural Gambia.
OSEI, I; Mendy, E; VAN ZANDVOORT, K; Jobe, O; Sarwar, G; WUTOR, BM; FLASCHE, S; Mohammed, NI; BRUCE, J; GREENWOOD, B; MACKENZIE, GA;
2024
Epidemics
Social contact data for the BHDSS and FWHDSS in the Gambia (2022)
OSEI, I; Mendy, E; Van Zandvoort, K; Jobe, O; Sarwar, MG; MOHAMMED, N; Bruce, J; GREENWOOD, B; MACKENZIE, GA;
2024
Zenodo
Community-acquired multidrug-resistant <i>Enterobacter cloacae</i> sepsis in a 25-month-old child in rural Gambia: A case report.
WUTOR, BM; Adefila, WO; Lamin, KM; Abdulsalam O, Y; Hossain, I; Molfa, M; Barjo, O; Salaudeen, R; OSEI, I; MACKENZIE, G;
2024
IDCases
Under-5 mortality surveillance in low-income and middle-income countries: insights from two Health and Demographic Surveillance Systems in rural Gambia.
WUTOR, BM; OSEI, I; Sarwar, G; Adefila, WO; Galega, LB; Hossain, I; Abdulsalam, Y; Lamin, KM; Baldeh, AM; Barry, B; Ezeani, E; MACKENZIE, G;
2024
BMJ global health
Stenotrophomonas maltophilia neonatal sepsis: a case report.
Adefila, WO; Osie, I; Keita, ML; WUTOR, BM; Yusuf, AO; Hossain, I; Molfa, M; Barjo, O; Salaudeen, R; MACKENZIE, G;
2024
Journal of medical case reports
Impact of pneumococcal conjugate vaccination on pneumococcal nasopharyngeal carriage in the Gambia: Population-based cross-sectional surveys.
MACKENZIE, GA; Hossain, I; SALAUDEEN, R; BADJI, H; Manjang, A; USUF, E; BOTTOMLEY, C; GREENWOOD, B; Hill, PC;
2024
Vaccine
Factors predicting mortality in hospitalised HIV-negative children with lower-chest-wall indrawing pneumonia and implications for management.
GALLAGHER, KE; Awori, JO; Knoll, MD; Rhodes, J; Higdon, MM; Hammitt, LL; Prosperi, C; Baggett, HC; Brooks, WA; Fancourt, N; Feikin, DR; Howie, SR C; Kotloff, KL; Tapia, MD; Levine, OS; Madhi, SA; Murdoch, DR; O'Brien, KL; Thea, DM; Baillie, VL; Ebruke, BE; Kamau, A; Moore, DP; Mwananyanda, L; Olutunde, EO; ... PERCH Study Group,
2024
PloS one
A genomic appraisal of invasive Salmonella Typhimurium and associated antibiotic resistance in sub-Saharan Africa.
Van Puyvelde, S; De Block, T; Sridhar, S; Bawn, M; Kingsley, RA; Ingelbeen, B; Beale, MA; Barbé, B; Jeon, HJ; Mbuyi-Kalonji, L; Phoba, M-F; Falay, D; Martiny, D; Vandenberg, O; Affolabi, D; Rutanga, JP; Ceyssens, P-J; Mattheus, W; Cuypers, WL; Van der Sande, MA B; Park, SE; Kariuki, S; Otieno, K; Lusingu, JP A; Mbwana, JR; ... Lunguya, O.
2023
Nature communications
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