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Professor Sinead Langan

FRCP MSc PhD

Professor
of Clinical Epidemiology and Wellcome Senior Clinical Fellow

Room
258f

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
0207 9272680

I trained in Medicine at the Queen's University of Belfast and continue to work clinically at St John's Institute of Dermatology, Guy's and St Thomas' Hospital. I joined the School in 2011 having completed my PhD at the University of Nottingham and  gained post-doctoral experience as a visiting scholar at the University of Pennsylvania, USA.

I am currently funded by a Wellcome Senior Clinical Fellowship in Science

I am former Chair of the European Dermatoepidemiology Network Steering committee (www.orgs.dermis.net/eden). I am also co-Chair and co-founder of the REporting of studies Conducted using Observational Routinely collected Data (RECORD) initiative (www.record-statement.org). I am Associate Director for Health Data Research UK London (www.hdruk.ac.uk).

Affiliations

Faculty of Epidemiology and Population Health
Department of Non-communicable Disease Epidemiology

Centres

Centre for Global Chronic Conditions

Teaching

I teach on a number of courses at the School, and I am currently the co-Course Organiser for the Certificate of Pharmacoepidemiology and Pharmacovigilance (PEPI)

Research

My research addresses two major areas:

  1. The epidemiology of skin diseases
  2. Reporting of observational research undertaken using routinely collected data

1. The epidemiology of skin diseases

My research addresses an important research gap, the causes, consequences and treatment of skin disease. Little is known about the epidemiology of skin diseases. My work focuses in particular on using the power of routine data sources to provide answers for important research questions. 

  • Eczema research  I am leading a programme of work on eczema using a variety of data sources. This work is supported by a Wellcome Senior Clinical fellowship in Science. I will identify eczema phenotypes using longitudinal population-based data and use a comprehensive approach to investigate if there are strong associations between eczema and major adverse health and social outcomes using large longitudinal population-based data. This cutting-edge work will make substantial contributions towards understanding eczema complexity and improving patient outcomes.
  • Other eczema-related work is focused on gene-environment interactions in eczema (in collaboration with the UK Translational Research Network in Dermatology), identifying costs and validating eczema diagnosis codes in UK general practice.

2.Reporting of observational research undertaken using routinely collected data

I co-founded the REporting of studies Conducted using Observational Routinely collected Data (RECORD) initiative (www.record-statement.org ) in 2012 in order to create reporting guidelines for studies undertaken using observational routinely-collected data. 

http://www.lshtm.ac.uk/eph/ncde/ehrresearchgroup/index.html

www.orgs.dermis.net/eden

www.record-statement.org

 

Research Area
Clinical databases
Health outcomes
Primary care
Public health
Systematic reviews
Vaccines
Electronic health records
Discipline
Epidemiology
Medicine
Disease and Health Conditions
Herpesviruses
Allergy
Asthma
Non-communicable diseases
Skin disease
Country
United Kingdom
Ireland
United States of America
Region
European Union
North America
World

Selected Publications

Is there an association between long-term antibiotics for acne and subsequent infection sequelae and antimicrobial resistance? A systematic review protocol.
Bhate K; Lin L-Y; Barbieri J; Leyrat C; Hopkins S; Stabler R; Shallcross L; Smeeth L; Francis NA; Mathur R
2020
BMJ open
Personalized prediction of daily eczema severity scores using a mechanistic machine learning model.
Hurault G; Domínguez-Hüttinger E; Langan SM; Williams HC; Tanaka RJ
2020
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
How 'benign' is cutaneous mastocytosis? A Danish registry-based matched cohort study
Kibsgaard L; Deleuran M; Flohr C; Langan S; Braae Olesen A; Vestergaard C
2020
International Journal of Women's Dermatology
Atopic dermatitis.
Langan SM; Irvine AD; Weidinger S
2020
Lancet (London, England)
Global reporting of cases of COVID-19 in psoriasis and atopic dermatitis: an opportunity to inform care during a pandemic.
Mahil SK; Yiu ZZN; Mason KJ; Dand N; Coker B; Wall D; Fletcher G; Bosma A; Capon F; Iversen L
2020
British Journal of Dermatology
Association Between Atopic Eczema and Cancer in England and Denmark.
Mansfield KE; Schmidt SAJ; Darvalics B; Mulick A; Abuabara K; Wong AYS; Sørensen HT; Smeeth L; Bhaskaran K; Dos Santos Silva I
2020
JAMA dermatology
Validation study of bullous pemphigoid and pemphigus vulgaris recording in routinely collected electronic primary healthcare records in England.
Persson MSM; Harman KE; Vinogradova Y; Langan SM; Hippisley-Cox J; Thomas KS; Gran S
2020
BMJ open
Partner bereavement and risk of chronic urticaria, alopecia areata and vitiligo: cohort studies in the UK and Denmark.
Wong AYS; Kjaersgaard A; Frøslev T; Forbes HJ; Mansfield KE; Silverwood RJ; Sørensen HT; Smeeth L; Schmidt SAJ; Langan SM
2020
The British Journal of Dermatology
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