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Professor Sinead Langan

FRCP MSc PhD

Professor
of Clinical Epidemiology and Wellcome Senior Clinical Fellow

Room
258f

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
0207 9272680

I trained in Medicine at the Queen's University of Belfast and continue to work clinically at St John's Institute of Dermatology, Guy's and St Thomas' Hospital. I joined the School in 2011 having completed my PhD at the University of Nottingham and  gained post-doctoral experience as a visiting scholar at the University of Pennsylvania, USA.

I am currently funded by a Wellcome Senior Clinical Fellowship in Science

I am former Chair of the European Dermatoepidemiology Network Steering committee (www.orgs.dermis.net/eden). I am also co-Chair and co-founder of the REporting of studies Conducted using Observational Routinely collected Data (RECORD) initiative (www.record-statement.org). I am Associate Director for Health Data Research UK London (www.hdruk.ac.uk).

Affiliations

Department of Non-communicable Disease Epidemiology
Faculty of Epidemiology and Population Health

Centres

Centre for Global Chronic Conditions

Teaching

I teach on a number of courses at the School, and I am currently the co-Course Organiser for the Certificate of Pharmacoepidemiology and Pharmacovigilance (PEPI)

Research

My research addresses two major areas:

  1. The epidemiology of skin diseases
  2. Reporting of observational research undertaken using routinely collected data

1. The epidemiology of skin diseases

My research addresses an important research gap, the causes, consequences and treatment of skin disease. Little is known about the epidemiology of skin diseases. My work focuses in particular on using the power of routine data sources to provide answers for important research questions. 

  • Eczema research  I am leading a programme of work on eczema using a variety of data sources. This work is supported by a Wellcome Senior Clinical fellowship in Science. I will identify eczema phenotypes using longitudinal population-based data and use a comprehensive approach to investigate if there are strong associations between eczema and major adverse health and social outcomes using large longitudinal population-based data. This cutting-edge work will make substantial contributions towards understanding eczema complexity and improving patient outcomes.
  • Other eczema-related work is focused on gene-environment interactions in eczema (in collaboration with the UK Translational Research Network in Dermatology), identifying costs and validating eczema diagnosis codes in UK general practice.

2.Reporting of observational research undertaken using routinely collected data

I co-founded the REporting of studies Conducted using Observational Routinely collected Data (RECORD) initiative (www.record-statement.org ) in 2012 in order to create reporting guidelines for studies undertaken using observational routinely-collected data. 

http://www.lshtm.ac.uk/eph/ncde/ehrresearchgroup/index.html

www.orgs.dermis.net/eden

www.record-statement.org

 

Research Area
Clinical databases
Health outcomes
Primary care
Public health
Systematic reviews
Vaccines
Electronic health records
Discipline
Epidemiology
Medicine
Disease and Health Conditions
Herpesviruses
Allergy
Asthma
Non-communicable diseases
Skin disease
Country
United Kingdom
Ireland
United States
Region
European Union
North America
World

Selected Publications

Risk of herpes zoster after exposure to varicella to explore the exogenous boosting hypothesis: self controlled case series study using UK electronic healthcare data.
Forbes H; Douglas I; Finn A; Breuer J; Bhaskaran K; Smeeth L; Packer S; Langan SM; Mansfield KE; Marlow R
2020
BMJ (Clinical research ed.)
The association between partner bereavement and melanoma: cohort studies in the U.K. and Denmark.
Wong AYS; Frøslev T; Dearing L; Forbes HJ; Mulick A; Mansfield KE; Silverwood RJ; Kjaersgaard A; Sørensen HT; Smeeth L
2020
British Journal of Dermatology
What is the evidence for interactions between filaggrin null mutations and environmental exposures in the aetiology of atopic dermatitis? A systematic review.
Blakeway H; Van-de-Velde V; Allen VB; Kravvas G; Palla L; Page MJ; Flohr C; Weller RB; Irvine AD; McPherson T
2019
British Journal of Dermatology
Partner Bereavement and Detection of Dementia: A UK-Based Cohort Study Using Routine Health Data.
Forbes HJ; Wong AYS; Morton C; Bhaskaran K; Smeeth L; Richards M; Schmidt SAJ; Langan SM; Warren-Gash C
2019
Journal of Alzheimer's Disease
The association of smoking and socioeconomic status on cutaneous melanoma: a population-based, data-linkage, case-control study.
Gibson JAG; Dobbs TD; Griffiths R; Song J; Akbari A; Whitaker S; Watkins A; Langan SM; Hutchings HA; Lyons RA
2019
The British journal of dermatology
Atopic eczema and fracture risk in adults: A population-based cohort study.
Lowe KE; Mansfield KE; Delmestri A; Smeeth L; Roberts A; Abuabara K; Prieto-Alhambra D; Langan SM
2019
Journal of Allergy and Clinical Immunology
Partner bereavement and risk of psoriasis and atopic eczema: cohort studies in the U.K. and Denmark.
Wong AYS; Frøslev T; Forbes HJ; Kjaersgaard A; Mulick A; Mansfield K; Silverwood RJ; Sørensen HT; Smeeth L; Schmidt SAJ
2019
The British Journal of Dermatology
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