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Jacqueline Knee

PhD MSPH

Assistant Professor
of Environmental Health & Microbiology

Room
411

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

I am an Assistant Professor in the Environmental Health Group, a multidisciplinary group of scientists and engineers focused on water, sanitation, and hygiene (WASH) related research. I joined LSHTM in 2019 as a Marshall Sherfield Fellow. I have a background in environmental health microbiology and hold a PhD in environmental engineering from the Georgia Institute of Technology and a Master of Science of Public Health from the UNC Gillings School of Global Public Health.

I am primarily interested in understanding the transmission of enteric pathogens in the environment, measuring their health impact, and evaluating WASH interventions aimed at reducing transmission and health risks in vulnerable populations. My main research project is the Maputo Sanitation (MapSan) trial, a health impact evaluation of an urban sanitation intervention in Maputo, Mozambique funded by the Bill and Melinda Gates Foundation. I also support several other research projects in the Environmental Health Group including the SaniVac trial, an assessment of the role of sanitation conditions and health status (specifically concurrent enteric infection) on the immunogenicity of an oral rotavirus vaccine in infants in Maputo, Mozambique. I am also interested in the use of serologic markers of immune response to enteric pathogens as an alternative metric of enteric infection and a potential surveillance tool for measuring enteric pathogen transmission.

Affiliations

Department of Disease Control
Faculty of Infectious and Tropical Diseases

Research

Research Area
Child health
Health impact analysis
Health outcomes
Hygiene
Sanitation
Water
Disease control
Environmental Health
Evaluation
Food
Global Health
Disease and Health Conditions
Diarrhoeal diseases
Infectious disease
Malnutrition
Tropical diseases
Soil-transmitted helminths
Country
Mozambique
Region
Sub-Saharan Africa (developing only)

Selected Publications

Elevated Fecal Mitochondrial DNA from Symptomatic Norovirus Infections Suggests Potential Health Relevance of Human Mitochondrial DNA in Fecal Source Tracking.
Zhu KJ; Suttner B; Knee J; Capone D; Moe CL; Stauber CE; Konstantinidis KT; Wallach TE; Pickering AJ; Brown J
2022
Environmental Science & Technology Letters
Impacts of an Urban Sanitation Intervention on Fecal Indicators and the Prevalence of Human Fecal Contamination in Mozambique.
Holcomb DA; Knee J; Capone D; Sumner T; Adriano Z; Nalá R; Cumming O; Brown J; Stewart JR
2021
Environmental science & technology
Effects of an urban sanitation intervention on childhood enteric infection and diarrhea in Maputo, Mozambique: A controlled before-and-after trial.
Knee J; Sumner T; Adriano Z; Anderson C; Bush F; Capone D; Casmo V; Holcomb D; Kolsky P; MacDougall A
2021
eLife
Human fecal contamination of water, soil, and surfaces in households sharing poor-quality sanitation facilities in Maputo, Mozambique.
Holcomb DA; Knee J; Sumner T; Adriano Z; de Bruijn E; Nalá R; Cumming O; Brown J; Stewart JR
2020
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
Risk factors for childhood enteric infection in urban Maputo, Mozambique: A cross-sectional study.
Knee J; Sumner T; Adriano Z; Berendes D; de Bruijn E; Schmidt W-P; Nalá R; Cumming O; Brown J
2018
PLoS neglected tropical diseases
See more Publications