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Professor Beate Kampmann

Staats Exam MD DTM&H PhD FRCPCH

Professor
Professor of Paediatric Infection & Immunity, Director of The Vaccine Centre

Room
367

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
0044 207612 7925

Professor Beate Kampmann joined the LSHTM from Imperial College London in May 2018 and is the Director of The Vaccine Centre @ LSHTM. She trained as a clinician-scientist in Paediatric Infectious Diseases in Germany, UK, France, USA and South Africa. Beate holds a Chair in Paediatric Infection & Immunity and was appointed as the Scientific Director (Theme Leader) for Vaccinology research at the MRC Unit The Gambia in July 2010. She directs a comprehensive childhood infection research program both in the UK and sub-saharan Africa.

As one of the three theme leaders at the MRC Unit in The Gambia, she oversees all research activities in infant immunology, childhood tuberculosis and molecular diagnostics, which range from basic research into innate and acquired immune responses to infection and vaccination in pregnant women and infants and the conduct of clinical trials of novel vaccines, adjuvants adn administration modalities. 

Over the last few years she has conducted a number of studies in both UK and West Africa  investigating the scientific and implementation challenges of maternal immunization.

She is the director of IMPRINT- the IMmunising PRegnant women and INfants network, one of the 5 MRC-funded networks for vaccines (www.imprint-network.co.uk).

Affiliations

Faculty of Infectious and Tropical Diseases
Department of Clinical Research

Centres

Maternal, Adolescent, Reproductive & Child Health (MARCH)
Tuberculosis (TB) Centre
Vaccine Centre

Teaching

Beate has a strong track record of developing the next generation of paediatric infectious diseases clinician scientists in the UK and Africa and has supervised a large group of PhD and MSc students in both locations. She was awarded the President's Medal for Excellence in research Supervision at Imperial College in 2015. She has acted as a mentor for many scientists and clinicians, in particular for women in science.

Research

The aim of Beate's research is to link scientific discoveries in the laboratory to the delivery of evidence-based care for children in the UK and Africa. 

She has conducted translational research in childhood tuberculosis for many years with a focus on correlates of protection, biomarkers for protection against disease progression and development and evaluation of novel diagnostics. She brought together investigators in Europe around childhood TB research by setting up the ptbnet- a network of clinicians and scientists aiming to improve the diagnosis, prevention and therapy of childhood TB.

Her vaccine-related work focuses on applying systems vaccinology tools to improve our insights into the development of the neonatal immune system, in the context of infections and vaccination.

She directs several projects exploring maternal immmunisation as a tool to decrease infant morbidity and mortality. This extends from the associated questions of transplacental antibody transfer, impact on developing neonatal immunity, role of co-infections and co-morbidities to the challenges of acceptancy and implementation of such an intervention.

Research Area
Child health
Clinical trials
Innate immunity
Maternal health
Perinatal health
T-cell immunology
Vaccines
Global Health
Immunisation
Neonatal health
Discipline
Immunology
Medicine
Vaccinology
Disease and Health Conditions
Diarrhoeal diseases
HIV/AIDS
Infectious disease
Meningitis
Pandemic diseases
Tuberculosis
Emerging Infectious Disease
Human papillomavirus (HPV)
Influenza
Respiratory disease
Tropical diseases
Country
Germany
United Kingdom
Gambia, The
Mali
Mozambique
Nigeria
Papua New Guinea
Senegal
Tanzania
United States
Vietnam
South Africa
Region
World

Selected Publications

Dynamic molecular changes during the first week of human life follow a robust developmental trajectory.
Lee AH; Shannon CP; Amenyogbe N; Bennike TB; Diray-Arce J; Idoko OT; Gill EE; Ben-Othman R; Pomat WS; van Haren SD
2019
Nature communications
Moving Toward Tuberculosis Elimination: Critical Issues for Research in Diagnostics and Therapeutics for Tuberculosis Infection.
Keshavjee S; Amanullah F; Cattamanchi A; Chaisson R; Dobos KM; Fox GJ; Gendelman HE; Gordon R; Hesseling A; Hoi LV
2018
American journal of respiratory and critical care medicine
Biomarkers for diagnosis of childhood tuberculosis: A systematic review.
Togun TO; MacLean E; Kampmann B; Pai M
2018
PloS one
Tuberculosis susceptibility and protection in children.
Basu Roy R; Whittaker E; Seddon JA; Kampmann B
2018
The Lancet. Infectious diseases
Evaluating UK National Guidance for Screening of Children for Tuberculosis A Prospective Multicenter Study
Kampmann B; Seddon JA; Paton J; Nademi Z; Keane D; Williams B; Williams A; Liebeschutz S; Riddell A; Bernatoniene J
2018
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
Association between functional antibody against Group B Streptococcus and maternal and infant colonization in a Gambian cohort
Le Doare K; Faal A; Jaiteh M; Sarfo F; Taylor S; Warburton F; Humphries H; Birt J; Jarju S; Darboe S
2017
VACCINE
Group B streptococcus and respiratory syncytial virus immunisation during pregnancy: a landscape analysis.
Heath PT; Culley FJ; Jones CE; Kampmann B; Le Doare K; Nunes MC; Sadarangani M; Chaudhry Z; Baker CJ; Openshaw PJM
2017
The Lancet. Infectious diseases
Factors Affecting Tb Transmission From Adult To Children Within Households In The Gambia
Mendy A; Tientcheu L; Ayorinde A; Coker E; Egere U; Kampmann B
2017
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
Identifying children with tuberculosis among household contacts in The Gambia
Egere U; Togun T; Sillah A; Mendy F; Otu J; Hoelscher M; Heinrich N; Hill PC; Kampmann B
2017
INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
Protecting the Newborn and Young Infant from Infectious Diseases: Lessons from Immune Ontogeny
Kollmann TR; Kampmann B; Mazmanian SK; Marchant A; Levy O
2017
IMMUNITY
Isoniazid preventive treatment among child contacts of adults with smear-positive tuberculosis in The Gambia
Egere U; Sillah A; Togun T; Kandeh S; Cole F; Jallow A; Able-Thomas A; Hoelscher M; Heinrich N; Hill PC
2016
PUBLIC HEALTH ACTION
The impact of BCG vaccination on tuberculin skin test responses in children is age dependent: evidence to be considered when screening children for tuberculosis infection
Seddon JA; Paton J; Nademi Z; Keane D; Williams B; Williams A; Welch SB; Liebeschutz S; Riddell A; Bernatoniene J
2016
THORAX
Role of human milk oligosaccharides in Group B Streptococcus colonisation
Andreas NJ; Al-Khalidi A; Jaiteh M; Clarke E; Hyde MJ; Modi N; Holmes E; Kampmann B; Le Doare KM
2016
CLINICAL & TRANSLATIONAL IMMUNOLOGY
Why the Convention on the Rights of the Child must become a guiding framework for the realization of the rights of children affected by tuberculosis
Roy RB; Brandt N; Moodie N; Motlagh M; Rasanathan K; Seddon JA; Detjen AK; Kampmann B
2016
BMC INTERNATIONAL HEALTH AND HUMAN RIGHTS
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