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Dr Rein Houben

PhD

Associate Professor
in Infectious Disease Epidemiology

Room
104b

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
+44(0)20 7927 2956

I came to the School in 2006, working primarily on the molecular epidemiology of Tuberculosis. After spending 3 years working on field studies in North Malawi, I moved back to London in 2012 to join the TB modelling and Analysis Consortium (www.tb-mac.org) and LSHTM TB modelling group.

Affiliations

Department of Infectious Disease Epidemiology
Faculty of Epidemiology and Population Health

Centres

Mathematical Modelling of Infectious Diseases
Tuberculosis (TB) Centre

Teaching

I have taught on a wide variety of courses in the In House and Distance Learning MSc Epidemiology. My organisational responsibilities have included EPM103: Practical Epidemiology (where I still run the Virtual Ethics Committee) and EPM302: Modelling and Dynamics of Infectious Diseases. Currently I am a module co-organiser for EP202: Statistical Methods in Epidemiology

Research

My main research focus is creating mathematical models that can inform TB policy and enable capacity building. I lead the development and implementation of TIME, a widely used TB modelling tool. I also work on models to improve our understanding of burden and treatment of latent TB infection as well as social determinants of TB.

Research Area
Modelling
Discipline
Epidemiology
Mathematical modelling
Disease and Health Conditions
Tuberculosis
Region
Euro area
South Asia
Sub-Saharan Africa (developing only)
Sub-Saharan Africa (all income levels)
World

Selected Publications

TIME Impact - a new user-friendly tuberculosis (TB) model to inform TB policy decisions.
Houben, R.M. ; Lalli, M. ; Sumner, T. ; Hamilton, M. ; Pedrazzoli, D. ; Bonsu, F. ; Hippner, P. ; Pillay, Y. ; Kimerling, M. ; Ahmedov, S. ; Pretorius, C. ; White, R.G. ;
BMC Med
Large-scale whole genome sequencing of M. tuberculosis provides insights into transmission in a high prevalence area.
Guerra-Assunção, J. ; Crampin, A. ; Houben, R. ; Mzembe, T. ; Mallard, K. ; Coll, F. ; Khan, P. ; Banda, L. ; Chiwaya, A. ; Pereira, R. ; McNerney, R. ; Fine, P. ; Parkhill, J. ; Clark, T. ; Glynn, J. ;
Elife
How can mathematical models advance tuberculosis control in high HIV prevalence settings?
Houben, R.M. ; Dowdy, D.W. ; Vassall, A. ; Cohen, T. ; Nicol, M.P. ; Granich, R.M. ; Shea, J.E. ; Eckhoff, P. ; Dye, C. ; Kimerling, M.E. ; White, R.G. ; TB MAC TB-HIV meeting participants, . ;
Int J Tuberc Lung Dis
The effect of diabetes and undernutrition trends on reaching 2035 global tuberculosis targets.
Odone, A. ; Houben, R.M. ; White, R.G. ; Lönnroth, K. ;
Lancet Diabetes Endocrinol
Using the TIME model in Spectrum to estimate tuberculosis-HIV incidence and mortality.
Pretorius, C. ; Glaziou, P. ; Dodd, P.J. ; White, R. ; Houben, R. ;
AIDS
Yield of HIV-associated tuberculosis during intensified case finding in resource-limited settings: a systematic review and meta-analysis.
Kranzer, K.; Houben, R.M.; Glynn, J.R.; Bekker, L.G.; Wood, R.; Lawn, S.D.;
Lancet Infect Dis
See all Dr Rein Houben's Publications