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Heidi Hopkins

MD

Associate Professor

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Since 2003, my professional focus has been clinical and implementation research on malaria diagnostic strategies and management of febrile patients in malaria-endemic areas. These interests have led to current work on fever etiology and antimicrobial resistance. I head the Clinical & Veterinary Sciences pillar of LSHTM’s Antimicrobial Resistance Centre.

Previous affiliations include the Foundation for Innovative New Diagnostics (FIND) in Uganda and Switzerland, and the Makerere University – University of California, San Francisco malaria research collaboration in Uganda.

My educational history includes degrees in anthropology (BA, University of Iowa), medicine (MD, Columbia College of Physicians & Surgeons, New York), and coursework in public health (University of California, Berkeley), as well as clinical training in internal medicine (Columbia-Presbyterian Medical Center, New York) and infectious diseases (University of California, San Francisco).

Affiliations

Department of Disease Control
Faculty of Infectious and Tropical Diseases

Centres

Malaria Centre
Antimicrobial Resistance Centre (AMR)

Teaching

I teach on LSHTM's Epidemiology & Control of Malaria module; the Epidemiology & Control of Communicable Disease module; the Infectious Disease Research Design, Management & Analysis course; and as of 2019, the Diploma in Tropical Medicine & Hygiene course. I also mentor Master's and doctoral students.

Research

I have served as investigator and coordinator for numerous efficacy, effectiveness, and implementation studies of point-of-care diagnostic tests in children, adults and pregnant women, and for evaluations of fever case management strategies. I have been based primarily in Uganda, and have also conducted collaborative research in other African and southeast Asian countries.

In 2018 we began FIEBRE (Febrile Illness Evaluation in a Broad Range of Endemicities), a prospective study of infectious causes of fever, and of antibiotic resistance, in inpatients and outpatients of all ages at multiple sites in Africa and Asia.

Other recent projects include synthesis of research results from ACT Consortium studies of malaria rapid diagnostic test (mRDT) implementation in various endemic settings; investigation of pfhrp2/3 gene deletions in P. falciparum that may affect mRDT results; and a collaborative effort to map data on non-malaria febrile illness.

My work includes collaboration with other academic researchers as well as with scientists and public health experts from the WHO, non-profit organizations, funding agencies, and diagnostics developers.

 

 

Disease and Health Conditions
Infectious disease
Malaria
Tropical diseases
Country
Burkina Faso
Laos
Mozambique
Malawi
Uganda
Zimbabwe

Selected Publications

Non-malarial febrile illness: a systematic review of published aetiological studies and case reports from Africa, 1980-2015.
Elven J; Dahal P; Ashley EA; Thomas NV; Shrestha P; Stepniewska K; Crump JA; Newton PN; Bell D; Reyburn H
2020
BMC Medicine
Febrile Illness Evaluation in a Broad Range of Endemicities (FIEBRE): protocol for a multisite prospective observational study of the causes of fever in Africa and Asia
Hopkins H; Bassat Q; Chandler CIR; Crump JA; Feasey NA; Ferrand RA; Kranzer K; Lalloo DG; Mayxay M; Newton PN
2020
BMJ Open
Patients with positive malaria tests not given artemisinin-based combination therapies: a research synthesis describing under-prescription of antimalarial medicines in Africa.
O'Boyle S; Bruxvoort KJ; Ansah EK; Burchett HED; Chandler CIR; Clarke SE; Goodman C; Mbacham W; Mbonye AK; Onwujekwe OE
2020
BMC medicine
Non-malarial febrile illness: a systematic review of published aetiological studies and case reports from Southern Asia and South-eastern Asia, 1980-2015.
Shrestha P; Dahal P; Ogbonnaa-Njoku C; Das D; Stepniewska K; Thomas NV; Hopkins H; Crump JA; Bell D; Newton PN
2020
BMC Medicine
Redefining typhoid diagnosis: what would an improved test need to look like?
Mather RG; Hopkins H; Parry CM; Dittrich S
2019
BMJ Global Health
pfhrp2 and pfhrp3 Gene Deletions That Affect Malaria Rapid Diagnostic Tests for Plasmodium falciparum: Analysis of Archived Blood Samples From 3 African Countries.
Thomson R; Beshir KB; Cunningham J; Baiden F; Bharmal J; Bruxvoort KJ; Maiteki-Sebuguzi C; Owusu-Agyei S; Staedke SG; Hopkins H
2019
The Journal of Infectious Diseases
Plasmodium falciparum parasites with histidine-rich protein 2 (pfhrp2) and pfhrp3 gene deletions in two endemic regions of Kenya.
Beshir KB; Sepúlveda N; Bharmal J; Robinson A; Mwanguzi J; Busula AO; de Boer JG; Sutherland C; Cunningham J; Hopkins H
2017
Scientific reports
The Impact of Introducing Malaria Rapid Diagnostic Tests on Fever Case Management: A Synthesis of Ten Studies from the ACT Consortium.
Bruxvoort KJ; Leurent B; Chandler CIR; Ansah EK; Baiden F; Björkman A; Burchett HED; Clarke SE; Cundill B; DiLiberto DD
2017
The American journal of tropical medicine and hygiene
Impact of introduction of rapid diagnostic tests for malaria on antibiotic prescribing: analysis of observational and randomised studies in public and private healthcare settings.
Hopkins H; Bruxvoort KJ; Cairns ME; Chandler CIR; Leurent B; Ansah EK; Baiden F; Baltzell KA; Björkman A; Burchett HED
2017
BMJ (Clinical research ed)
Rapid diagnostic tests versus clinical diagnosis for managing people with fever in malaria endemic settings.
Odaga J; Sinclair D; Lokong JA; Donegan S; Hopkins H; Garner P
2014
The Cochrane database of systematic reviews
Highly sensitive detection of malaria parasitemia in a malaria-endemic setting: performance of a new loop-mediated isothermal amplification kit in a remote clinic in Uganda.
Hopkins H; González IJ; Polley SD; Angutoko P; Ategeka J; Asiimwe C; Agaba B; Kyabayinze DJ; Sutherland CJ; Perkins MD
2013
The Journal of infectious diseases
Rapid diagnostic tests for malaria at sites of varying transmission intensity in Uganda.
Hopkins H; Bebell L; Kambale W; Dokomajilar C; Rosenthal PJ; Dorsey G
2008
The Journal of infectious diseases
See more Publications