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Professor Kat Holt

Professor
of Microbial Systems Genomics

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Kat is a computational biologist specialising in infectious disease genomics, and is Professor of Microbial Systems Genomics at LSHTM’s Department of Infection Biology and a Professor in the Department of Infectious Diseases at Monash University in Australia. She has a BA/BSc (Hons) majoring in Biochemistry, Applied Statistics and Philosophy (University of Western Australia); a Master of Epidemiology (University of Melbourne); and a PhD in Molecular Biology (University of Cambridge and Sanger Institute).

Kat is currently Editor-in-Chief of the UK Microbiology Society journal Microbial Genomics and a HHMI-Gates International Research Scholar.

Publications can be found via Google Scholar & ORCID

Affiliations

Faculty of Infectious and Tropical Diseases
Department of Infection Biology

Centres

Antimicrobial Resistance Centre

Research

Kat’s research group uses computational genomics and sequencing, phylogenetics, spatiotemporal analysis and epidemiology to study the evolution and transmission of bacterial pathogens, including tropical diseases such as typhoid, dysentery, E. coli diarrhea and tuberculosis; and hospital associated pathogens such as Klebsiella and Acinetobacter. Kat is particularly interested in the global health crisis of antimicrobial resistance (AMR), using genomic epidemiology tools to understand the evolutionary history and global dissemination of multidrug resistant pathogens, and developing new tools for prospective surveillance and tracking of emerging problems in the public health and clinical infectious disease space. Kat is also interested in human, animal and environmental microbiomes, and their role in chronic disease, infectious disease, and horizontal gene transfer. Her lab develops bioinformatics software when needed, and have developed numerous bioinformatics tools for pathogen genotyping and nanopore sequencing.

Research Area
Bacteria
Drug resistance
Public health
Surveillance
Global Health
Outbreaks
Discipline
Genetic epidemiology
Genomics
Bacteriology
Microbiology
Molecular biology
Bioinformatics
Disease and Health Conditions
Diarrhoeal diseases
Infectious disease
Tuberculosis
Allergy
Asthma
Emerging Infectious Disease
Hospital acquired infection
Country
Australia
France
United Kingdom
Kenya
Malawi
Norway
Nepal
Papua New Guinea
Singapore
Tanzania
United States
Vietnam
Region
East Asia & Pacific (developing only)
East Asia & Pacific (all income levels)
Europe & Central Asia (all income levels)
South Asia
Sub-Saharan Africa (all income levels)
World