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Dr Martin Goodier

BSc, D.Phil

Assistant Professor
Immunology

Room
236

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
020 7927 2815

Affiliations

Immunology and Infection Department
Faculty of Infectious and Tropical Diseases

Centres

Vaccine Centre

Research

Dr Goodier's research focus is on the biology of human Natural Killer cells; how the function of NK cells changes throughout life and how exposure to infections, including herpes viruses and HIV-1 influences these changes. Understanding how vaccines, including influenza and hepatitis B, induce protective mechanisms in NK cells is also a primary research goal.

 

Research Area
Innate immunity
Vaccines
Viruses
Discipline
Immunology
Disease and Health Conditions
Herpesviruses
HIV/AIDS
Influenza
Country
United Kingdom
Gambia, The
Senegal
Region
European Union
Sub-Saharan Africa (developing only)

Selected Publications

Influenza Vaccination Generates Cytokine-Induced Memory-like NK Cells: Impact of Human Cytomegalovirus Infection.
Goodier, M.R.; Rodriguez-Galan, A.; Lusa, C.; Nielsen, C.M.; Darboe, A.; Moldoveanu, A.L.; White, M.J.; Behrens, R.; Riley, E.M.;
J Immunol
Differential frequency of NKG2C/KLRC2 deletion in distinct African populations and susceptibility to Trachoma: a new method for imputation of KLRC2 genotypes from SNP genotyping data.
Goncalves, A.; Makalo, P.; Joof, H.; Burr, S.; Ramadhani, A.; Massae, P.; Malisa, A.; Mtuy, T.; Derrick, T.; Last, A.R.; Nabicassa, M.; Cassama, E.; Houghton, J.; Palmer, C.D.; Pickering, H.; Burton, M.J.; Mabey, D.C.; Bailey, R.L.; Goodier, M.R.; Holland, M.J.; Roberts, C.H.;
Hum Genet
Impaired NK Cell Responses to Pertussis and H1N1 Influenza Vaccine Antigens in Human Cytomegalovirus-Infected Individuals.
Nielsen, C.M.; White, M.J.; Bottomley, C.; Lusa, C.; Rodríguez-Galán, A.; Turner, S.E.; Goodier, M.R.; Riley, E.M.;
J Immunol
Rapid natural killer cell differentiation in a population with near universal human cytomegalovirus infection is attenuated by NKG2C deletions.
Goodier, M.R.; White, M.J.; Darboe, A.; Nielsen, C.M.; Goncalves, A.; Bottomley, C.; Moore, S.E.; Riley, E.M.;
Blood
Differential activation of CD57-defined natural killer cell subsets during recall responses to vaccine antigens
White, M.J.; Nielsen, C.M.; McGregor, R.H.C.; Riley, E.M.; Goodier, M.R.
Immunology
Elevated plasma lipopolysaccharide is not sufficient to drive natural killer cell activation in HIV-1-infected individuals.
Gregson, J.N. ; Steel, A. ; Bower, M. ; Gazzard, B.G. ; Gotch, F.M. ; Goodier, M.R. ;
AIDS
NKG2C+ NK cells are enriched in AIDS patients with advanced-stage Kaposi's sarcoma.
Goodier, M.R. ; Mela, C.M. ; Steel, A. ; Gazzard, B. ; Bower, M. ; Gotch, F. ;
J Virol
See all Dr Martin Goodier's Publications