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Dr Tony Fletcher

Associate Professor

United Kingdom

I am part time employed at the LSHTM. I have been at LSHTM since 1992,

and was also at UKHSA (formerly PHE) from 2013 to 2023.

I contribute to several studies of PFAS (perfluorinated alkyl substance) research,

on PFAS-exposed communities in Ronneby, Sweden and in Veneto, Italy.

I was Adjunct Research Professor in Environmental Health in the

School of Public Health, Boston University, Massachusetts, USA,

2007-2017 and elected President of the International Society for

Environmental Epidemiology: Presidential term 2004-5.

Previously employments: IARC, Lyon;

MRC Environmental Epidemiology Unit, Southampton:

Birmingham University; Aston University.

Affiliations

Department of Public Health, Environments and Society
Faculty of Public Health and Policy

Centres

Centre for Evaluation

Teaching

I contribute to teaching on the Public Health Msc, in

particular for the Environmental Epidemiology Module, and Environmental

Health Policy in the Environmental Health stream.

Research

My principal research interests are environmental epidemiology

(predominately on disease risks in relation to drinking water

contaminants; cancer in relation to occupation, arsenic and drinking

water; and respiratory disease in relation to air pollution) and

environmental health risk assessment (embracing quantitative risk

assessment, risk perception, environmental health policy making in

general and standard setting for chemicals in particular). A major

recent effort has been on perfluorinated chemicals.

I am co-investigator on studies of health effects of perfluoroalkyl

substance (PFAS) fire fighting foam exposures in Sweden. This programme

led by Gothenberg and Lund Universities, is in a community exposed via

drinking water exposure contaminated by fire fighting foams from a

nearby military airfield. I am PI on project funded by FORMAS: “The role of renal

and intestinal pathways for elimination and half-life of perfluorinated alkyl acids”. 

I am co-investigator in three projects funded by FORTE, on analyses of serum PFAS

and serum hormones and lipids, on exposure modelling and on

birth outcome/infant health in relation to in-utero exposure to PFAS 

I am co-investigator on studies of health effects of perfluoroalkyl substance

(PFAS) in drinking water in Veneto Italy: “Cross-sectional

epidemiological study on the association between internal dose of PFAS

and anthropometric and bio-humoral parameters in the exposed Veneto

population”, (University of Padova).

Past research

C8 Science Panel Community study.

I co-directed an epidemiological research programme on the potential

health effects of Perfluoro-octanoic acid (PFOA or C8) and other

perfluorinated chemicals in a community adjacent to a Teflon

manufacturing facility in West Virginia, USA. These studies include a

cross sectional study of Cancer, Immune function, Liver and Hormone

disorders in the community and a Geographical Study of Cancer Incidence

in the counties around the plant. More details at http://www.c8sciencepanel.org/study.html

Research Area
Environmental health
Region
Euro area

Selected Publications

Estimation of per- and polyfluoroalkyl substances (PFAS) half-lives in human studies: a systematic review and meta-analysis.
Rosato, I; Bonato, T; FLETCHER, T; Batzella, E; Canova, C;
2023
Environmental Research
Risk factors for SARS-Cov-2 infection at a United Kingdom electricity-generating company: a test-negative design case-control study
RUTTER, C; Van Tongeren, M; FLETCHER, T; Rhodes, S; Chen, Y; Hall, I; Warren, N; PEARCE, N;
2023
medRxiv
Associations between Mixture of Perfluoroalkyl Substances and Lipid Profile in a Highly Exposed Adult Community in the Veneto Region.
Batzella, E; Zare Jeddi, M; Pitter, G; Russo, F; FLETCHER, T; Canova, C;
2022
International journal of environmental research and public health
Transmission and Control of SARS-CoV-2 in the Food Production Sector: A Rapid Narrative Review of the Literature.
Hosseini, P; Mueller, W; Rhodes, S; PEMBREY, L; Van Tongeren, M; PEARCE, N; Loh, M; FLETCHER, T;
2022
International journal of environmental research and public health
PFAS Concentrations and Cardiometabolic Traits in Highly Exposed Children and Adolescents.
Canova, C; Di Nisio, A; Barbieri, G; Russo, F; FLETCHER, T; Batzella, E; Dalla Zuanna, T; Pitter, G;
2021
International Journal of Environmental Research and Public Health
PFAS Concentrations and Cardiometabolic Traits in Highly Exposed Children and Adolescents
Canova, C; Nisio, AD; Barbieri, G; Russo, F; FLETCHER, T; Dalla Zuanna, T; Pitter, G;
2021
Preprints.org
Occupational differences in COVID-19 incidence, severity, and mortality in the United Kingdom: Available data and framework for analyses.
PEARCE, N; Rhodes, S; Stocking, K; PEMBREY, L; VAN VELDHOVEN, K; BRICKLEY, EB; ROBERTSON, S; DAVOREN, D; Nafilyan, V; Windsor-Shellard, B; FLETCHER, T; Van Tongeren, M;
2021
Wellcome Open Research
Systemic PFOS and PFOA exposure and disturbed lipid homeostasis in humans: what do we know and what not?
Fragki, S; Dirven, H; FLETCHER, T; Grasl-Kraupp, B; Bjerve Gützkow, K; Hoogenboom, R; Kersten, S; Lindeman, B; Louisse, J; Peijnenburg, A; Piersma, AH; Princen, HM G; Uhl, M; Westerhout, J; Zeilmaker, MJ; Luijten, M;
2021
Critical reviews in toxicology
Perfluoroalkyl substance excretion: Effects of organic anion-inhibiting and resin-binding drugs in a community setting.
Ducatman, A; Luster, M; FLETCHER, T;
2021
Environmental toxicology and pharmacology
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