Dr Segun Fatumo


Assistant Professor
of Genetic Epidemiology & Bioinformatics

MRC/UVRI & LSHTM Uganda Research Unit
Uganda Medical Informatics Centre

Dr. Segun Fatumo is an Assistant Professor of Genetic Epidemiology and Bioinformatics at MRC/UVRI Uganda and London School of Hygiene and Tropical Medicine (LSHTM). He leads The African Computational Genomics (TACG) Research group. His group’s expertise includes but not limited to GWAS, meta-analysis, Multi-variates GWAS, Genetic Risk Score, Fine Mapping, Mendelian randomisation studies and Drug Targets Discovery. He was recently (July 2020) awarded a prestigious Wellcome International Intermediate Fellowship to lead an innovative research programme at the MRC/UVRI and LSHTM.

Dr Fatumo’s research largely focuses on the genetic impact of non-communicable diseases in Africa. He is actively involved in capacity building across Africa including teaching and/or postgraduate supervision at Makerere University Uganda, the University of Sciences, Techniques, and Technology of Bamako (USTTB) Mali, and Covenant University Nigeria and the H3Africa Bioinformatics Network (H3ABioNet) node at the Centre for Genomics Research and Innovation, National Biotechnology Development Agency (CGRI-NABDA) in Abuja, Nigeria. He is an Associate Fellow of the Higher Education Academy (AFHEA) in the UK and teaches on MSc programmes at LSHTM and Queen Mary University of London (QMUL).

Dr Fatumo co-leads the Nigerian Non-Communicable Diseases - Genetic Heritage Study (NCD-GHS) Consortium and co-directs the Nigerian cardio-metabolic genomic study (NicGen)  - A concerted effort to see over 100,000 Nigerians participate in the eponymous study, which will seek to understand the genetic basis of the highly prevalent non-Communicable Diseases (NCDs) in Nigeria such as chronic kidney, diabetes, obesity among others.

Dr Fatumo received postdoctoral training in genetic epidemiology at the University of Cambridge and Wellcome Sanger Institute and a postdoctoral fellowship in Bioinformatics at the University of Georgia, Athens, USA. Prior to that, He had postgraduate training in applied Bioinformatics at the University of Cologne, Germany and Ph.D. in Computer Science (Bioinformatics specialization) from Covenant University, Nigeria. During his Ph.D. Programme, Segun developed a model which identified twenty-two (22) potential novel drug targets against malaria, some of which have been tested and validated experimentally.

Dr. Fatumo is the Founder and pioneer President of the Nigerian Bioinformatics and Genomics Network. He is the immediate past vice-president of the African Society for Bioinformatics and Computational Biology (ASBCB).


Faculty of Epidemiology and Population Health
Department of Non-communicable Disease Epidemiology


I teach on various masters' degree programmes and supervise doctoral students.


My work largely centres on the genetic basis of Non-communicable diseases, particularly chronic kidney disease, lipid metabolism, coronary artery and infectious disease, and the use of genetic tools for causal inference.

Research Area
Human genetics
Genetic epidemiology
Disease and Health Conditions
Kidney disease
Non-communicable diseases
United Kingdom
European Union
Sub-Saharan Africa (all income levels)

Selected Publications

The trans-ancestral genomic architecture of glycemic traits.
Chen J; Spracklen CN; Marenne G; Varshney A; Corbin LJ; Luan J; Willems SM; Wu Y; Zhang X; Horikoshi M
Nature genetics
Non-communicable diseases pandemic and precision medicine: Is Africa ready?
Chikowore T; Kamiza AB; Oduaran OH; Machipisa T; Fatumo S
Metabolic Traits and Stroke Risk in Individuals of African Ancestry: Mendelian Randomization Analysis.
Fatumo S; Karhunen V; Chikowore T; Sounkou T; Udosen B; Ezenwa C; Nakabuye M; Soremekun O; Daghlas I; Ryan DK
Transcription-translation error: In-silico investigation of the structural and functional impact of deleterious single nucleotide polymorphisms in GULP1 gene
Soremekun OS; Ezenwa C; Soliman M; Chikowore T; Nashiru O; Fatumo S
Informatics in Medicine Unlocked
The Nigerian Bioinformatics and Genomics Network (NBGN): a collaborative platform to advance bioinformatics and genomics in Nigeria.
Fatumo S; Ebenezer TE; Ekenna C; Isewon I; Ahmad U; Adetunji C; Oladipo EK; Adebiyi M; Adebiyi E; Nashiru O
Global health, epidemiology and genomics
Distinct genetic architectures and environmental factors associate with host response to the γ2-herpesvirus infections.
Sallah N; Miley W; Labo N; Carstensen T; Fatumo S; Gurdasani D; Pollard MO; Dilthey AT; Mentzer AJ; Marshall V
Computational and drug target analysis of functional single nucleotide polymorphisms associated with Haemoglobin Subunit Beta (HBB) gene.
Soremekun OS; Ezenwa C; Isewon I; Soliman M; Idowu O; Nashiru O; Fatumo S
Computers in biology and medicine
See more Publications