Dr Abdi Elmi
BSc MSc PhD
Senior Scientific Officer
I have a Bachelor of Science degree in Microbial Biotechnology from University of Surrey, a Master of Science from Nottingham University and a Ph.D. from LSHTM. I joined the School in 2004. I am responsible for the management of a number of ITD laboratories. I am Health and Safety Supervisor for the Department of PMB, Deputy Radiation Supervisor of the School, a member of Gene Modification Advisory Committee and Scientific Manager for Professor Brendan Wren’s research group. I also carry out research in Bacterial pathogenesis, virulence and host immune response. I maintain regular output of high quality research and publish in leading research journals contributing significantly the School's strategy and policy of submission to future Research Excellence Framework (REF) programmes.
I am co-organiser of Molecular Biology and Recombinant DNA Technique (Module 3333). I also deliver a range of lectures across a range of modules.
I supervise Master and Doctoral research students. Currently I am co-supervisor of one PhD student.
I act as a Tutor for MSc students and advisor for PhD students.
My research focuses characterising the role of Outer Membrane Vesicles (OMVs) in Bacterial pathogenesis. This area of research has emerged as major area and we are beginning to appreciate that OMVs have an important role in bacterial virulence.
- Characterisation of the biological functions of the different compositions of C. jejuni OMVs.
- Understanding of how some proteins are incorporated within the OMVs while most proteins are spared. We know little about this critical process, in contrast to our understanding of the role of OMVs in pathogenesis.
- Characterisation of underlying mechanisms that lead to C. jejuni OMVs interaction with IECs eventually leading to the delivering of OMVs content into the IECs cytosol. We focus on the role of C. jejuni outer membrane proteins that have been reported to be involved in adhesion, as well as with other virulence associated proteins found in the periplasm.