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Alison Elliott

MA MBBS MD DTH&H FRCP

Professor
of Tropical Medicine

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
0207 927 2116

Alison Elliott is a physician, specialising in infectious diseases and tropical medical research.  After a degree in Natural Sciences and medical training in the UK she went to Zambia in 1988, and undertook early studies on the interaction between tuberculosis and HIV infection.  Between 1992 and 1995 she undertook an infectious diseases fellowship in the USA, with research on the immunology of tuberculosis at the National Jewish Center in Denver, Colorado.  Since 1996 she has been working in Uganda, supported by Wellcome Trust funding, at the Medical Research Council Unit at the Uganda Virus Research Institute (UVRI), where she is head of the Co-infection Studies Programme.

Affiliations

Department of Clinical Research
Faculty of Infectious and Tropical Diseases

Teaching

Alison's main "teaching" activity is in research capacity building in Uganda.  She currently leads the Wellcome Trust funded Makerere-UVRI Centre of Excellence for Infection and Immunity Research and Training (MUII; www.muii.org.ug) which aims to attract bright young Ugandans to develop an internationally competitive research career in the field of Infection and Immunity.  This programme is a collaboration between the Uganda Virus Research Institute, Makerere University, LSHTM and Cambridge University.  Activities include Open Days for schools, undergraduate internships, and a Masters, PhD and post-doctoral fellowship scheme; as well as a new short course in Immunology (Immunology in the Tropics) and a series of Hot Topics seminars presented by scientists who are world leaders in their fields as they visit Uganda.

Research

Alison's research interests focus on the immuno-modulating effects of chronic infections.  After early studies on HIV and tuberculosis she developed an interest in the immuno-modulating effects of helminths.  Current research particularly addresses the effects of maternal helminth infection, and helminth infections in young children, on outcomes in childhood.  In addition, she is leading a cluster-randomised trial among fishing villages in the islands of Lake Victoria, Uganda, investigating the effects of standard, versus intenstive, intervention against helminth infections on responses to vaccines, to microbial pathogens and to allergens.  

Research Area
Child health
Clinical trials
Helminths
Discipline
Immunoepidemiology
Epidemiology
Immunology
Medicine
Disease and Health Conditions
Tuberculosis
Allergy
Asthma
Neglected Tropical Diseases (NTDs)
Country
Uganda
Region
Sub-Saharan Africa (developing only)

Selected Publications

Helminths are positively associated with atopy and wheeze in Ugandan fishing communities: results from a cross-sectional survey.
Webb, E.L.; Nampijja, M.; Kaweesa, J.; Kizindo, R.; Namutebi, M.; Nakazibwe, E.; Oduru, G.; Kabubi, P.; Kabagenyi, J.; Nkurunungi, G.; Kizito, D.; Muhangi, L.; Akello, M.; Verweij, J.J.; Nerima, B.; Tukahebwa, E.; Elliott, A.M.; LaVIISWA trial team, .; COLLABORATORS;Sanya, R. ; Mirembe, B. ; Okello, J. ; Levin, J. ; Zziwa, C. ; Tumusiime, J. ; Sewankambo, M. ; Nsubuga, D. ; Cose, S. ; Wammes, L. ; Niwagaba, E. ; Kabami, G. ; Abayo, E. ; Muwonge, F. ; Abiriga, D. ; Nannozi, V. ; Kaweesa, J. ;
Allergy
Capacity for science in sub-Saharan Africa.
Elliott, A. ; Nerima, B. ; Bagaya, B. ; Kambugu, A. ; Joloba, M. ; Cose, S. ; Pantaleo, G. ; Yazdanbakhsh, M. ; Mabey, D. ; Dunne, D. ; Moffett, A. ; Rwakishaya, E.K. ; Kaleebu, P. ; Mbidde, E.K. ;
Lancet
Helminth therapy or elimination: epidemiological, immunological, and clinical considerations.
Wammes, L.J.; Mpairwe, H.; Elliott, A.M.; Yazdanbakhsh, M.;
Lancet Infect Dis
Effect of single-dose anthelmintic treatment during pregnancy on an infant's response to immunisation and on susceptibility to infectious diseases in infancy: a randomised, double-blind, placebo-controlled trial.
Webb, E.L.; Mawa, P.A.; Ndibazza, J.; Kizito, D.; Namatovu, A.; Kyosiimire-Lugemwa, J.; Nanteza, B.; Nampijja, M.; Muhangi, L.; Woodburn, P.W.; Akurut, H.; Mpairwe, H.; Akello, M.; Lyadda, N.; Bukusuba, J.; Kihembo, M.; Kizza, M.; Kizindo, R.; Nabulime, J.; Ameke, C.; Namujju, P.B.; Tweyongyere, R.; Muwanga, M.; Whitworth, J.A.; Elliott, A.M.;
Lancet
Anthelminthic treatment during pregnancy is associated with increased risk of infantile eczema: randomised-controlled trial results.
Mpairwe, H.; Webb, E.L.; Muhangi, L.; Ndibazza, J.; Akishule, D.; Nampijja, M.; Ngom-wegi, S.; Tumusime, J.; Jones, F.M.; Fitzsimmons, C.; Dunne, D.W.; Muwanga, M.; Rodrigues, L.C.; Elliott, A.M.;
Pediatr Allergy Immunol
Effect of Praziquantel Treatment during Pregnancy on Cytokine Responses to Schistosome Antigens: Results of a Randomized, Placebo-Controlled Trial
Tweyongyere, R.; Mawa, P.A.; Ngom-Wegi, S.; Ndibazza, J.; Duong, T.; Vennervald, B.J.; Dunne, D.W.; Katunguka-Rwakishaya, E.; Elliott, A.M.
Journal of Infectious Diseases
A Randomized, Double-Blind, Placebo-Controlled Trial of the Use of Prednisolone as an Adjunct to Treatment in HIV-1-Associated Pleural Tuberculosis.
Elliott, A.M.; Luzze, H.; Quigley, M.A.; Nakiyingi, J.S.; Kyaligonza, S.; Namujju, P.B.; Ducar, C.; Ellner, J.J.; Whitworth, J.A.; Mugerwa, R.; Johnson, J.L.; Okwera, A.;
J Infect Dis
Helminth Infection Is Not Associated with Faster Progression of HIV Disease in Coinfected Adults in Uganda.
Brown, M.; Kizza, M.; Watera, C.; Quigley, M.A.; Rowland, S.; Hughes, P.; Whitworth, J.A.; Elliott, A.M.;
J Infect Dis
See all Alison Elliott's Publications