Professor Alison Elliott


of Tropical Medicine

Keppel Street
United Kingdom

0207 927 2116

Alison Elliott is a physician, specialising in infectious diseases and tropical medical research.  After a degree in Natural Sciences and medical training in the UK she went to Zambia in 1988, and undertook early studies on the interaction between tuberculosis and HIV infection.  Between 1992 and 1995 she undertook an infectious diseases fellowship in the USA, with research on the immunology of tuberculosis at the National Jewish Center in Denver, Colorado.  Since 1996 she has been working in Uganda, supported by Wellcome Trust and MRC funding, at the Medical Research Council / Uganda Virus Research Institute (UVRI) and LSHTM Uganda Research Unit, where she is Theme Leader for Vaccines and Immunity and Head of the Immunomodulation and Vaccines Programme.


Department of Clinical Research
Faculty of Infectious and Tropical Diseases


Tuberculosis (TB) Centre
Vaccine Centre


Alison's main "teaching" activity is in research capacity building in Uganda.  She currently leads the Wellcome Trust funded Makerere-UVRI Centre of Excellence for Infection and Immunity Research and Training (MUII; which aims to attract bright young Ugandans to develop an internationally competitive research career in the field of Infection and Immunity.  This programme is a collaboration between the Uganda Virus Research Institute, Makerere University, LSHTM and Cambridge University (with many other, much-valued, regional and international partners).  Activities include Open Days for schools, undergraduate internships, and a Masters, PhD and post-doctoral fellowship scheme; as well as a flagship short course in Immunology (Immunology in the Tropics) and a series of Hot Topics seminars presented by scientists who are world leaders in their fields as they visit Uganda.


Alison's research interests focus on the immuno-modulating effects of chronic infections.  After early studies on HIV and tuberculosis she developed an interest in the immuno-modulating effects of helminths.  Current research particularly addresses the effects of early life exposures on outcomes in adolescence, based on the Entebbe Mother and Baby Study birth cohort (  The team has just completed a cluster-randomised trial among fishing villages in the islands of Lake Victoria, Uganda, investigating the effects of standard, versus intenstive, intervention against helminth infections on responses to vaccines, to microbial pathogens and to allergens; and is about to embark on a series of new trials investigating the role and reversibility of immunodulating parasitic infections in population differences in vaccines responses.

Research Area
Child health
Clinical trials
Adolescent health
Disease and Health Conditions
Neglected Tropical Diseases (NTDs)
Sub-Saharan Africa (developing only)

Selected Publications

The impact of intensive versus standard anthelminthic treatment on allergy-related outcomes, helminth infection intensity and helminth-related morbidity in Lake Victoria fishing communities, Uganda: results from the LaVIISWA cluster randomised trial.
Sanya, R.E. ; Nkurunungi, G. ; Hoek Spaans, R. ; Nampijja, M. ; O'Hara, G. ; Kizindo, R. ; Oduru, G. ; Kabuubi Nakawungu, P. ; Niwagaba, E. ; Abayo, E. ; Kabagenyi, J. ; Zziwa, C. ; Nakazibwe, E. ; Tumusiime, J. ; Kaweesa, J. ; Muwonge Kakooza, F. ; Akello, M. ; Lubyayi, L. ; Verweij, J. ; Nash, S. ; van Ree, R. ; Mpairwe, H. ; Tukahebwa, E. ; Webb, E.L. ; Elliott, A.M. ; LaVIISWA trial team, . ;
Clin Infect Dis
Capacity for science in sub-Saharan Africa.
Elliott, A. ; Nerima, B. ; Bagaya, B. ; Kambugu, A. ; Joloba, M. ; Cose, S. ; Pantaleo, G. ; Yazdanbakhsh, M. ; Mabey, D. ; Dunne, D. ; Moffett, A. ; Rwakishaya, E.K. ; Kaleebu, P. ; Mbidde, E.K. ;
Helminth therapy or elimination: epidemiological, immunological, and clinical considerations.
Wammes, L.J.; Mpairwe, H.; Elliott, A.M.; Yazdanbakhsh, M.;
Lancet Infect Dis
Maternal hookworm modifies risk factors for childhood eczema: results from a birth cohort in Uganda.
Mpairwe, H. ; Ndibazza, J. ; Webb, E.L. ; Nampijja, M. ; Muhangi, L. ; Apule, B. ; Lule, S. ; Akurut, H. ; Kizito, D. ; Kakande, M. ; Jones, F.M. ; Fitzsimmons, C.M. ; Muwanga, M. ; Rodrigues, L.C. ; Dunne, D.W. ; Elliott, A.M. ;
Pediatr Allergy Immunol
Effect of single-dose anthelmintic treatment during pregnancy on an infant's response to immunisation and on susceptibility to infectious diseases in infancy: a randomised, double-blind, placebo-controlled trial.
Webb, E.L.; Mawa, P.A.; Ndibazza, J.; Kizito, D.; Namatovu, A.; Kyosiimire-Lugemwa, J.; Nanteza, B.; Nampijja, M.; Muhangi, L.; Woodburn, P.W.; Akurut, H.; Mpairwe, H.; Akello, M.; Lyadda, N.; Bukusuba, J.; Kihembo, M.; Kizza, M.; Kizindo, R.; Nabulime, J.; Ameke, C.; Namujju, P.B.; Tweyongyere, R.; Muwanga, M.; Whitworth, J.A.; Elliott, A.M.;
Anthelminthic treatment during pregnancy is associated with increased risk of infantile eczema: randomised-controlled trial results.
Mpairwe, H.; Webb, E.L.; Muhangi, L.; Ndibazza, J.; Akishule, D.; Nampijja, M.; Ngom-wegi, S.; Tumusime, J.; Jones, F.M.; Fitzsimmons, C.; Dunne, D.W.; Muwanga, M.; Rodrigues, L.C.; Elliott, A.M.;
Pediatr Allergy Immunol
Effect of Praziquantel Treatment during Pregnancy on Cytokine Responses to Schistosome Antigens: Results of a Randomized, Placebo-Controlled Trial
Tweyongyere, R.; Mawa, P.A.; Ngom-Wegi, S.; Ndibazza, J.; Duong, T.; Vennervald, B.J.; Dunne, D.W.; Katunguka-Rwakishaya, E.; Elliott, A.M.
Journal of Infectious Diseases
A Randomized, Double-Blind, Placebo-Controlled Trial of the Use of Prednisolone as an Adjunct to Treatment in HIV-1-Associated Pleural Tuberculosis.
Elliott, A.M.; Luzze, H.; Quigley, M.A.; Nakiyingi, J.S.; Kyaligonza, S.; Namujju, P.B.; Ducar, C.; Ellner, J.J.; Whitworth, J.A.; Mugerwa, R.; Johnson, J.L.; Okwera, A.;
J Infect Dis
See all Professor Alison Elliott's Publications