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Dr Moses Egesa

Research Fellow

MRC/UVRI and LSHTM Uganda Research Unit
Entebbe
Uganda

I'm a parasite immunologist focusing on Schistosoma mansoni. I am currently based at the Uganda Virus Research Institute in Entebbe, Uganda. I joined LSHTM at the end of 2021 as a Research Fellow. I completed my PhD on immune responses during the skin-stage infection at Makerere University. 

Affiliations

MRC/UVRI and LSHTM Uganda Research Unit

Teaching

A tutor at the LSHTM, London on the Module IDM213 Immunology of Infections and Vaccines

A lecturer at Makerere University, Kampala for MSc Immunolgy and Clinical Microbiology, MMED Internal Medicine, and MMED Microbiology. 

Research

My research vision is to develop optimal vaccines against neglected parasitic infections such as schistosomiasis, leading to improved health of populations at risk in Africa and the tropics. My research has three foci. 

Focus 1. Identifying Schistosoma-specific protective human immune responses to guide vaccine design and (preclinical) development

Focus 2. Integrating controlled human infection models in vaccine trials to accelerate schistosomiasis vaccine development.

Focus 3. Building the capacity for schistosomiasis research in an endemic setting

Research Area
Immunology
Parasites
Parasitology
Disease and Health Conditions
Schistosomiasis
Neglected Tropical Diseases (NTDs)
Country
Uganda
Netherlands
United Kingdom
Region
Sub-Saharan Africa (all income levels)

Selected Publications

Uganda Schistosomiasis Symposium 2023: understanding morbidity drivers and developing controlled human infection models for vaccine research.
EGESA, M; Kiberu, D; Sanya, RE; Alabi, A; Sonnet, F; Koopman, JP R; Baluku, JB; Oguttu, DW; Driciru, E; Odongo, M; Walusimbi, B; ELLIOTT, AM; NKURUNUNGI, G;
2023
Trends in parasitology
Ethical and practical considerations arising from community consultation on implementing controlled human infection studies using Schistosoma mansoni in Uganda.
EGESA, M; SSALI, A; Tumwesige, E; Kizza, M; Driciru, E; Luboga, F; Roestenberg, M; SEELEY, J; ELLIOTT, AM;
2022
Global Bioethics
Antibody responses to Schistosoma mansoni schistosomula antigens.
EGESA, M; Lubyayi, L; Jones, FM; Van Diepen, A; Chalmers, IW; Tukahebwa, EM; Bagaya, BS; Hokke, CH; Hoffmann, KF; Dunne, DW; ELLIOTT, AM; Yazdanbakhsh, M; Wilson, S; COSE, S;
2018
Parasite immunology
Schistosoma mansoni schistosomula antigens induce Th1/Pro-inflammatory cytokine responses.
EGESA, M; Lubyayi, L; Tukahebwa, EM; Bagaya, BS; Chalmers, IW; Wilson, S; Hokke, CH; Hoffmann, KF; Dunne, DW; Yazdanbakhsh, M; Labuda, LA; COSE, S;
2018
Parasite immunology
Rethinking Schistosomiasis Vaccine Development: Synthetic Vesicles.
EGESA, M; Hoffmann, KF; Hokke, CH; Yazdanbakhsh, M; COSE, S;
2017
Trends in parasitology
Partnership to Develop an Inter-Disciplinary Schistosomiasis Research Training Program in Uganda
Nakanjako, D; EGESA, M; Byakwaga, H; Tolo, CU; Byaruhanga, AM; Beinamaryo, P; Banturaki, G; Nakiyingi, L; Ocama, P; Kamya, MR; Elliott, AM;
2025
The American Journal of Tropical Medicine and Hygiene
Identification of training needs in schistosomiasis research to build capacity for schistosomiasis control in Uganda.
Nakanjako, D; EGESA, M; Byakwaga, H; Tolo, CU; Byaruhanga, AM; Beinamaryo, P; Banturaki, G; Nakiyingi, L; Ocama, P; Kamya, MR; ELLIOTT, AM;
2025
Tropical medicine & international health : TM & IH
T cell responses in repeated controlled human schistosome infection compared to natural exposure
Driciru, E; Koopman, JP R; Steenbergen, S; Sonnet, F; Stam, KA; De Bes-Roeleveld, H; Iliopoulou, E; Janse, JJ; Sijtsma, J; Nambuya, I; Hilt, ST; König, M; Kruize, Y; Casacuberta-Partal, M; EGESA, M; Van Dam, GJ; Corstjens, PL A M; Van Lieshout, L; Mpairwe, H; MacDonald, AS; Yazdanbakhsh, M; Elliott, AM; Roestenberg, M; Houlder, EL;
2025
Cold Spring Harbor Laboratory
Identification of a Clade-Specific HLA-C*03:02 CTL Epitope GY9 Derived from the HIV-1 p17 Matrix Protein.
Kyobe, S; Mwesigwa, S; NKURUNUNGI, G; Retshabile, G; EGESA, M; Katagirya, E; Amujal, M; Mlotshwa, BC; Williams, L; Sendagire, H; On Behalf Of The CAfGEN Consortium,; Kiragga, D; Mardon, G; Matshaba, M; Hanchard, NA; Kyosiimire-Lugemwa, J; Robinson, D;
2024
International journal of molecular sciences
The rise of pathogen genomics in Africa.
Mboowa, G; Kakooza, F; EGESA, M; Tukwasibwe, S; Kanyerezi, S; Sserwadda, I; R Kidenya, B; Kabahita, JM; Namaganda, MM; Nsubuga, M; Nabisubi, P; Ayitewala, A; Kebirungi, G; Nakafu, E; Akwii, NP;
2024
F1000Research
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