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Professor Ian DOUGLAS

BSc MSc PhD

Professor
of Pharmacoepidemiology

Room
Room 248a

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
+44 (0)20 7927 2968

I am a pharmacoepidemiolgist and previouly studied physiology and completed a PhD in Manchester. Since then I have spent several years at the UK Medicines & Healthcare Products Regulatory Agency and in the pharmaceutcial industry investigating adverse effects of drugs - both in clinical trials and post-marketing. I completed the MSc in epidemiology at LSHTM in 2005.

Affiliations

Department of Non-communicable Disease Epidemiology
Faculty of Epidemiology and Population Health

Teaching

I am Programme Director for the MSc in Epidmiology. I teach on the MSc as well as the LSHTM short courses in pharmacoepdemiology and pharmacovigilance.

Research

I'm interested in pharmacoepidemiology, and in particular, how we can use large linked electronic healthcare record databases to investigate the effects of drugs - both harmful and beneficial. I am exploring methodologies to minimise some of the biases inherent in the research of drug effects, and my main current areas of interest are case-only approaches to study design and how we can determine whether routine care data can be used to estimate the intended effects of medications.

Research Area
Drug discovery and development
Pharmacovigilance
Primary care
Public health
Electronic health records
Discipline
Pharmacoepidemiology
Epidemiology
Medicine
Pharmacology

Selected Publications

Evaluation of the risk of cardiovascular events with clarithromycin using both propensity score and self-controlled study designs.
Root, A.A.; Wong, A.Y.; Ghebremichael-Weldeselassie, Y.; Smeeth, L.; Bhaskaran, K.; Evans, S.J.; Brauer, R.; Wong, I.C.; Navaratnam, V.; Douglas, I.;
2016
Br J Clin Pharmacol
Glitazone Treatment and Incidence of Parkinson's Disease among People with Diabetes: A Retrospective Cohort Study.
Brauer, R. ; Bhaskaran, K. ; Chaturvedi, N. ; Dexter, D.T. ; Smeeth, L. ; Douglas, I. ;
2015
PLoS Med
Antipsychotic drugs and risks of myocardial infarction: a self-controlled case series study.
Brauer, R.; Smeeth, L.; Anaya-Izquierdo, K.; Timmis, A.; Denaxas, S.C.; Farrington, C.P.; Whitaker, H.; Hemingway, H.; Douglas, I.;
2014
Eur Heart J
Clopidogrel and interaction with proton pump inhibitors: comparison between cohort and within person study designs.
Douglas, I.J. ; Evans, S.J. ; Hingorani, A.D. ; Grosso, A.M. ; Timmis, A. ; Hemingway, H. ; Smeeth, L. ;
2012
BMJ
Effect of statins on a wide range of health outcomes: a cohort study validated by comparison with randomized trials
Smeeth, L.; Douglas, I.; Hall, A.J.; Hubbard, R.; Evans, S.
2009
British Journal of Clinical Pharmacology
The risk of fractures associated with thiazolidinediones: a self-controlled case-series study
Douglas, I.J.; Evans, S.J.; Pocock, S.; Smeeth, L.
2009
PLoS Med
See all Professor Ian DOUGLAS's Publications