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Dr Enny Cruz

PhD

Assistant Professor

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Dr Enny Paixao Cruz is a Sir Henry Wellcome Fellow of Infectious Disease Epidemiology in the Faculty of Epidemiology and Population Health at the London School of Hygiene and Tropical Medicine (UK). Dr Paixao's research focuses on the use of electronic health data in middle-income countries, infectious disease and maternal and child health. In collaboration with partners at CIDACS-Fiocruz (http://cidacs.bahia.fiocruz.br/), she uses big data approaches to investigate the effect of obstetric and pre-natal conditions, congenital infections, and other potential social and environmental determinants and impact of social policies on birth, growth, morbidity, and survival, overall and in subgroups of interest in a dynamic Brazilian birth cohort.

Affiliations

Department of Infectious Disease Epidemiology
Faculty of Epidemiology and Population Health

Centres

Centre for Maternal Adolescent Reproductive & Child Health (MARCH)

Teaching

Dr Paixao teaching areas are public health and epidemiology. At LSHTM she is a distance learning CO-Module Organizer "EPM101 Fundamentals of Epidemiology". She is also a tutor for face to face program "Basic Epidemiology" and "Extended Epidemiology".  She supervises MSc student projects.

Research

Research Area
Child health
Health inequalities
Infectious disease policy
Maternal health
Public health
Surveillance
Viruses
Impact evaluation
Inequalities
Neonatal health
Outbreaks
Discipline
Epidemiology
Disease and Health Conditions
Infectious disease
Syphilis
Emerging Infectious Disease
Neglected Tropical Diseases (NTDs)
Zoonotic disease
Dengue
Zika
Country
Brazil
Region
Latin America & Caribbean (all income levels)

Selected Publications

Effectiveness of CoronaVac, ChAdOx1 nCoV-19, BNT162b2, and Ad26.COV2.S among individuals with previous SARS-CoV-2 infection in Brazil: a test-negative, case-control study.
Cerqueira-Silva T; Andrews JR; Boaventura VS; Ranzani OT; de Araújo Oliveira V; Paixão ES; Júnior JB; Machado TM; Hitchings MDT; Dorion M
2022
The Lancet Infectious diseases
Vaccination plus previous infection: protection during the omicron wave in Brazil.
Cerqueira-Silva T; de Araujo Oliveira V; Paixão ES; Florentino PTV; Penna GO; Pearce N; Werneck GL; Barreto ML; Boaventura VS; Barral-Netto M
2022
The Lancet Infectious Diseases
Vaccine effectiveness of heterologous CoronaVac plus BNT162b2 in Brazil.
Cerqueira-Silva T; Katikireddi SV; de Araujo Oliveira V; Flores-Ortiz R; Júnior JB; Paixão ES; Robertson C; Penna GO; Werneck GL; Barreto ML
2022
Nature Medicine
Evaluating the effect of Bolsa Familia, Brazil's conditional cash transfer programme, on maternal and child health: A study protocol.
Falcão IR; Ribeiro-Silva RDC; Alves FJO; Ortelan N; Silva NJ; Fiaccone RL; de Almeida MF; Pescarini JM; Lisboa CS; Júnior EPP
2022
PloS one
Audiological follow-up of children with congenital Zika syndrome.
Muniz LF; Maciel RJF; Ramos DS; Albuquerque KMG; Leão ÂC; Van Der Linden V; Paixão ES; Brickley EB; Cordeiro MT; Leitão GGS
2022
Heliyon
Mortality from Congenital Zika Syndrome - Nationwide Cohort Study in Brazil.
Paixao ES; Cardim LL; Costa MCN; Brickley EB; de Carvalho-Sauer RCO; Carmo EH; Andrade RFS; Rodrigues MS; Veiga RV; Costa LC
2022
The New England journal of medicine
CoronaVac vaccine is effective in preventing symptomatic and severe COVID-19 in pregnant women in Brazil: a test-negative case-control study.
Paixao ES; Wong KLM; Alves FJO; de Araújo Oliveira V; Cerqueira-Silva T; Júnior JB; Machado TM; Junior EPP; Boaventura VS; Penna GO
2022
BMC Medicine
Socioeconomic risk markers of arthropod-borne virus (arbovirus) infections: a systematic literature review and meta-analysis.
Power GM; Vaughan AM; Qiao L; Sanchez Clemente N; Pescarini JM; Paixão ES; Lobkowicz L; Raja AI; Portela Souza A; Barreto ML
2022
BMJ Global Health
Differences in risk factors for incident and recurrent preterm birth: a population-based linkage of 3.5 million births from the CIDACS birth cohort.
Rocha AS; de Cássia Ribeiro-Silva R; Fiaccone RL; Paixao ES; Falcão IR; Alves FJO; Silva NJ; Ortelan N; Rodrigues LC; Ichihara MY
2022
BMC MEDICINE
Cohort Profile: The 100 Million Brazilian Cohort.
Barreto ML; Ichihara MY; Pescarini JM; Ali MS; Borges GL; Fiaccone RL; Ribeiro-Silva RDC; Teles CA; Almeida D; Sena S
2021
International journal of epidemiology
Associations between Maternal Dietary Patterns and Infant Birth Weight in the NISAMI Cohort: A Structural Equation Modeling Analysis.
da Mota Santana J; de Oliveira Queiroz VA; Pereira M; Paixão ES; Brito SM; Dos Santos DB; Oliveira AM
2021
NUTRIENTS
Impact of COVID-19 pandemic on time series of maternal mortality ratio in Bahia, Brazil: analysis of period 2011-2020.
de Carvalho-Sauer RDCO; Costa MDCN; Teixeira MG; do Nascimento EMR; Silva EMF; Barbosa MLA; da Silva GR; Santos TP; Paixao ES
2021
BMC Pregnancy and Childbirth
Factors associated with small- and large-for-gestational-age in socioeconomically vulnerable individuals in the 100 Million Brazilian Cohort.
Falcão IR; Ribeiro-Silva RDC; de Almeida MF; Fiaccone RL; Silva NJ; Paixao ES; Ichihara MY; Rodrigues LC; Barreto ML
2021
The American journal of clinical nutrition
Risk of mortality for small newborns in Brazil, 2011-2018: A national birth cohort study of 17.6 million records from routine register-based linked data.
Paixao ES; Blencowe H; Falcao IR; Ohuma EO; Rocha ADS; Alves FJO; Costa MDCN; Suárez-Idueta L; Ortelan N; Smeeth L
2021
The Lancet Regional Health - Americas
Associations between cesarean delivery and child mortality: A national record linkage longitudinal study of 17.8 million births in Brazil.
Paixao ES; Bottomley C; Pescarini JM; Wong KLM; Cardim LL; Ribeiro Silva RDC; Brickley EB; Rodrigues LC; Oliveira Alves FJ; Leal MDC
2021
PLoS medicine
Using the Robson classification to assess caesarean section rates in Brazil: an observational study of more than 24 million births from 2011 to 2017.
Paixao ES; Bottomley C; Smeeth L; da Costa MCN; Teixeira MG; Ichihara MY; Gabrielli L; Barreto ML; Campbell OMR
2021
BMC pregnancy and childbirth
Methods to evaluate COVID-19 vaccine effectiveness, with an emphasis on quasi-experimental approaches.
Pescarini JM; Teixeira CSS; Cruz EP; Ortelan N; Pinto PFPS; Ferreira AJF; Alves FJO; Pinto Junior EP; Falcão IR; Rocha ADS
2021
Ciencia & saude coletiva
Conditional cash transfer program and child mortality: A cross-sectional analysis nested within the 100 Million Brazilian Cohort.
Ramos D; da Silva NB; Ichihara MY; Fiaccone RL; Almeida D; Sena S; Rebouças P; Júnior EPP; Paixão ES; Ali S
2021
PLoS medicine
Long-term impact of a conditional cash transfer programme on maternal mortality: a nationwide analysis of Brazilian longitudinal data.
Rasella D; Alves FJO; Rebouças P; de Jesus GS; Barreto ML; Campello T; Paixao ES
2021
BMC Medicine
COVID-19, Food Insecurity and Malnutrition: A Multiple Burden for Brazil.
Ribeiro-Silva RDC; Pereira M; Aragão É; Guimarães JMDM; Ferreira AJF; Rocha ADS; Silva NDJ; Teixeira CSS; Falcão IR; Paixao ES
2021
Frontiers in nutrition
Time trends and social inequalities in child malnutrition: nationwide estimates from Brazil's food and nutrition surveillance system, 2009-2017.
Ribeiro-Silva RDC; Silva NDJ; Felisbino-Mendes MS; Falcão IR; de Andrade RDCS; Silva SA; Nilson EAF; Spaniol AM; Fiaccone RL; Paixão E
2021
Public health nutrition
Recurrence of preterm births: A population-based linkage with 3.5 million live births from the CIDACS Birth Cohort.
Rocha AS; de Cássia Ribeiro-Silva R; Paixao ES; Falcão IR; Alves FJO; Ortelan N; de Almeida MF; Fiaccone RL; Rodrigues LC; Ichihara MY
2021
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
Combined association of obesity and other cardiometabolic diseases with severe COVID-19 outcomes: a nationwide cross-sectional study of 21 773 Brazilian adult and elderly inpatients.
Silva NDJ; Ribeiro-Silva RDC; Ferreira AJF; Teixeira CSS; Rocha AS; Alves FJO; Falcão IR; Pinto EDJ; Santos CADST; Fiaccone RL
2021
BMJ open
Seroprevalence of Chikungunya virus and living conditions in Feira de Santana, Bahia-Brazil.
Teixeira MG; Skalinski LM; Paixão ES; Costa MDCN; Barreto FR; Campos GS; Sardi SI; Carvalho RH; Natividade M; Itaparica M
2021
PLoS neglected tropical diseases
Classification algorithm for congenital Zika Syndrome: characterizations, diagnosis and validation.
Veiga RV; Schuler-Faccini L; França GVA; Andrade RFS; Teixeira MG; Costa LC; Paixão ES; Costa MDCN; Barreto ML; Oliveira JF
2021
Scientific Reports
Examining the quality of record linkage process using nationwide Brazilian administrative databases to build a large birth cohort.
Almeida D; Gorender D; Ichihara MY; Sena S; Menezes L; Barbosa GCG; Fiaccone RL; Paixão ES; Pita R; Barreto ML
2020
BMC Medical Informatics and Decision Making
Social distancing measures to control the COVID-19 pandemic: potential impacts and challenges in Brazil.
Aquino EML; Silveira IH; Pescarini JM; Aquino R; Souza-Filho JAD; Rocha ADS; Ferreira A; Victor A; Teixeira C; Machado DB
2020
Ciencia & saude coletiva
Covid-19: The time to shield all pregnant frontline workers is now.
Brickley EB; Paixão ES
2020
BMJ (Clinical research ed.)
Cross-sectional study of the anthropometric characteristics of children with congenital Zika syndrome up to 12 months of life.
Carvalho-Sauer RDCOD; Costa MDCN; Paixão ES; de Jesus Silva N; Barreto FR; Teixeira MG
2020
BMC Pediatrics
New Insights on the Zika Virus Arrival in the Americas and Spatiotemporal Reconstruction of the Epidemic Dynamics in Brazil.
Costa LC; Veiga RV; Oliveira JF; Rodrigues MS; Andrade RFS; Paixão ES; Teixeira MG; Costa MDCN; Cardim LL; Carmo EH
2020
Viruses
Factors associated with low birth weight at term: a population-based linkage study of the 100 million Brazilian cohort.
Falcão IR; Ribeiro-Silva RDC; de Almeida MF; Fiaccone RL; Dos S Rocha A; Ortelan N; Silva NJ; Paixao ES; Ichihara MY; Rodrigues LC
2020
BMC Pregnancy and Childbirth
Case Fatality Rate Related to Microcephaly Congenital Zika Syndrome and Associated Factors: A Nationwide Retrospective Study in Brazil †.
N Costa MC; Cardim LL; Teixeira MG; Barreto ML; Carvalho-Sauer RDCOD; Barreto FR; Carvalho MSI; Oliveira WK; França GVA; Carmo EH
2020
VIRUSES-BASEL
Interdependence between confirmed and discarded cases of dengue, chikungunya and Zika viruses in Brazil: A multivariate time-series analysis.
Oliveira JF; Rodrigues MS; Skalinski LM; Santos AES; Costa LC; Cardim LL; Paixão ES; Costa MDCN; Oliveira WK; Barreto ML
2020
PLOS ONE
Cohort Profile: Centro de Integração de Dados e Conhecimentos para Saúde (CIDACS) Birth Cohort.
Paixao ES; Cardim LL; Falcao IR; Ortelan N; Silva NDJ; Rocha ADS; Sena S; Almeida D; Ramos DO; Alves FJO
2020
International journal of epidemiology
The need for fast-track, high-quality and low-cost studies about the role of the BCG vaccine in the fight against COVID-19.
Pereira M; Paixão E; Trajman A; de Souza RA; da Natividade MS; Pescarini JM; Pereira SM; Barreto FR; Ximenes R; Dalcomo M
2020
RESPIRATORY RESEARCH
Repercussions of Zika virus emergency on the health of the population of Tocantins state, Brazil, 2015 and 2016: a descriptive study.
Rodrigues MDSP; Costa MDCN; Barreto FR; Brustulin R; Paixão ES; Teixeira MG
2020
Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil
Zika virus infection in pregnancy and adverse fetal outcomes in São Paulo State, Brazil: a prospective cohort study.
Sanchez Clemente N; Brickley EB; Paixão ES; De Almeida MF; Gazeta RE; Vedovello D; Rodrigues LC; Witkin SS; Passos SD
2020
SCIENTIFIC REPORTS
Investigation of an outbreak of acute respiratory disease in an indigenous village in Brazil: Contribution of Influenza A(H1N1)pdm09 and human respiratory syncytial viruses.
Cardoso AM; Resende PC; Paixao ES; Tavares FG; Farias YN; Barreto CTG; Pantoja LN; Ferreira FL; Martins AL; Lima ÂB
2019
PloS one
Dengue during pregnancy and live birth outcomes: a cohort of linked data from Brazil.
Paixão ES; Campbell OM; Teixeira MG; Costa MC; Harron K; Barreto ML; Leal MB; Almeida MF; Rodrigues LC
2019
BMJ open
Validating linkage of multiple population-based administrative databases in Brazil.
Paixão ES; Campbell OMR; Rodrigues LC; Teixeira MG; Costa MDCN; Brickley EB; Harron K
2019
PloS one
Impact evaluation of Zika epidemic on congenital anomalies registration in Brazil: An interrupted time series analysis.
Paixão ES; Rodrigues MS; Cardim LL; Oliveira JF; L C C; Costa MDCN; Barreto ML; Rodrigues LC; Smeeth L; Andrade RFS
2019
PLoS neglected tropical diseases
Impact evaluation of Zika epidemic on congenital anomalies registration in Brazil: An interrupted time series analysis
Paixão ES; Rodrigues MS; Cardim LL; Oliveira JF; L. C. C; Costa MDCN; Barreto ML; Rodrigues LC; Smeeth L; Andrade RFS
2019
Seroprevalence of Chikungunya Virus after Its Emergence in Brazil.
Dias JP; Costa MDCN; Campos GS; Paixão ES; Natividade MS; Barreto FR; Itaparica MSC; Goes C; Oliveira FLS; Santana EB
2018
Emerging infectious diseases
Dengue in pregnancy and maternal mortality: a cohort analysis using routine data.
Paixao ES; Harron K; Campbell O; Teixeira MG; Costa MDCN; Barreto ML; Rodrigues LC
2018
Scientific reports
Asymptomatic Prenatal Zika Virus Infection and Congenital Zika Syndrome.
Paixao ES; Leong W-Y; Rodrigues LC; Wilder-Smith A
2018
Open forum infectious diseases
Chikungunya chronic disease: a systematic review and meta-analysis.
Paixão ES; Rodrigues LC; Costa MDCN; Itaparica M; Barreto F; Gérardin P; Teixeira MG
2018
Transactions of the Royal Society of Tropical Medicine and Hygiene
Symptomatic Dengue during Pregnancy and Congenital Neurologic Malformations.
Paixão ES; Teixeira MG; Costa MDCN; Barreto ML; Rodrigues LC
2018
Emerging infectious diseases
Conquistas do SUS no enfrentamento das doenças transmissíveis
Teixeira MG; Costa MDCN; Paixão ESD; Carmo EH; Barreto FR; Penna GO
2018
Ciência & Saúde Coletiva
Leprosy in children under 15 years of age in Brazil: A systematic review of the literature.
Vieira MCA; Nery JS; Paixão ES; Freitas de Andrade KV; Oliveira Penna G; Teixeira MG
2018
PLoS neglected tropical diseases
Symptomatic dengue infection during pregnancy and the risk of stillbirth in Brazil, 2006-12: a matched case-control study.
Paixão ES; Costa MDCN; Teixeira MG; Harron K; de Almeida MF; Barreto ML; Rodrigues LC
2017
The Lancet infectious diseases
Evaluation of record linkage of two large administrative databases in a middle income country: stillbirths and notifications of dengue during pregnancy in Brazil.
Paixão ES; Harron K; Andrade K; Teixeira MG; Fiaccone RL; Costa MDCN; Rodrigues LC
2017
BMC medical informatics and decision making
History, Epidemiology, and Clinical Manifestations of Zika: A Systematic Review.
Paixão ES; Barreto F; Teixeira MDG; Costa MDCN; Rodrigues LC
2016
American journal of public health
What we need to know about Zika virus.
Paixão ES; Rodrigues LC
2016
British journal of hospital medicine (London, England
Dengue during pregnancy and adverse fetal outcomes: a systematic review and meta-analysis.
Paixão ES; Teixeira MG; Costa MDCN; Rodrigues LC
2016
The Lancet infectious diseases
Trends and factors associated with dengue mortality and fatality in Brazil.
Paixão ES; Costa MDCN; Rodrigues LC; Rasella D; Cardim LL; Brasileiro AC; Teixeira MGLC
2015
Revista da Sociedade Brasileira de Medicina Tropical
Arterial hypertension and skin allergy are risk factors for progression from dengue to dengue hemorrhagic fever: a case control study.
Teixeira MG; Paixão ES; Costa MDCN; Cunha RV; Pamplona L; Dias JP; Figueiredo CA; Figueiredo MAA; Blanton R; Morato V
2015
PLoS neglected tropical diseases
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