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Dr Fiona Cresswell

Clinical Assistant Professor

United Kingdom

I am a practicing clinician in HIV and Sexual Health at University Hospital Sussex and an active clinical academic working on improving the treatment of HIV and opportunistic infections in sub-Saharan Africa.

I hope to support the effective and equitable implementation of long-acting HIV treatments in programmatic care settings in Africa through clinical trials, clinical pharmacology, translational and implementation research. I am Lead Investigator of a phase III randomised clinical trial called IMPALA 'Improving HIV outcomes in Africa with Long-acting Antiretroviral therapy' so I work closely with colleagues at the trial coordinating centre at MRC/UVRI-LSHTM Uganda Research Unit and collaborators in Uganda, Kenya and South Africa. I am also site-investigator on the Cabotegravir and Rilpivirine Efficacy and Safety (CARES) study in Uganda.

My PhD research was with the Infectious Disease Institute in Uganda where i worked with the meningitis research team on improving the diagnosis and treatment of TB meningitis. I continue to study TB meningitis an Investigator on the HARVEST multi-country trial of high-dose rifampicin for TB meningitis at the Infectious Diseases Institute, Uganda, Caprisa in South Africa, Oxford University Clinical Research Unit in Indonesia, Universities Padjadjaran, Radboud University in the Netherlands and University of Minnesota.

Affiliations

Department of Clinical Research
Faculty of Infectious and Tropical Diseases

Teaching

Coordinator of TB module on Diploma in Tropical Medicine and Hygiene 2023
Tutor on the East African Diploma in Tropical Medicine and Hygiene since 2010.
HIV/TB module lead on the EADTMH in 2019.
I enjoy small group bedside teaching.
I have examined medical student OSCEs for Makerere University in Uganda and Brighton and Sussex Medical School

Research

My interests lie in HIV treatment, the diagnosis and treatment of HIV-related opportunistic infections, and sexually transmitted infections.
Research Area
Clinical care
Clinical guidelines
Clinical trials
Diagnostics
Global Health
Medicines
Pharmacokinetics
Sexual health
Epidemiology
Medicine
Pharmacology
Disease and Health Conditions
HIV/AIDS
Syphilis
Tropical diseases
Tuberculosis
Infectious diseases
Sexually transmitted infections
Country
Indonesia
Netherlands
Uganda
United Kingdom
United States
Region
Sub-Saharan Africa (developing only)

Selected Publications

Standardized Urine-Based Tuberculosis (TB) Screening With TB-Lipoarabinomannan and Xpert MTB/RIF Ultra in Ugandan Adults With Advanced Human Immunodeficiency Virus Disease and Suspected Meningitis.
CRESSWELL, FV; ELLIS, J; Kagimu, E; Bangdiwala, AS; Okirwoth, M; Mugumya, G; Rutakingirwa, M; Kasibante, J; Quinn, CM; Ssebambulidde, K; Rhein, J; Nuwagira, E; Tugume, L; Martyn, E; Skipper, CP; Muzoora, C; GRINT, D; Meya, DB; Bahr, NC; ELLIOTT, AM; Boulware, DR;
2020
OPEN FORUM INFECTIOUS DISEASES
Xpert MTB/RIF Ultra for the diagnosis of HIV-associated tuberculous meningitis: a prospective validation study.
CRESSWELL, FV; Tugume, L; Bahr, NC; Kwizera, R; Bangdiwala, AS; Musubire, AK; Rutakingirwa, M; Kagimu, E; Nuwagira, E; Mpoza, E; Rhein, J; Williams, DA; Muzoora, C; GRINT, D; ELLIOTT, AM; Meya, DB; Boulware, DR; ASTRO-CM team,;
2020
The Lancet. Infectious diseases
Erratum to: The Changing Epidemiology of HIV-Associated Adult Meningitis, Uganda 2015-2017.
ELLIS, J; Bangdiwala, AS; CRESSWELL, FV; Rhein, J; Nuwagira, E; Ssebambulidde, K; Tugume, L; Rajasingham, R; Bridge, SC; Muzoora, C; Meya, DB; Boulware, DR;
2019
OPEN FORUM INFECTIOUS DISEASES
Recent Developments in Tuberculous Meningitis Pathogenesis and Diagnostics.
CRESSWELL, FV; Davis, AG; Sharma, K; BASU ROY, R; Ganiem, AR; Kagimu, E; Solomons, R; Wilkinson, RJ; Bahr, NC; Thuong, NT T; Tuberculous Meningitis International Research Cons,;
2019
Wellcome Open Research
Pilot project demonstrating the feasibility of HIV antiretroviral therapy waste bottle collection and recycling
CB Muyise, R; CRESSWELL, F; Kwizera, R; AO Laker, E; C Owarwo, N; B Meya, D; Lamorde, M;
2024
Wellcome Open Res
Integrated management of cryptococcal meningitis and concurrent opportunistic infections to improve outcomes in advanced HIV disease: a randomised strategy trial
ELLIS, J; Nsangi, L; Bangdiwala, A; Hale, G; Gakuru, J; Kagimu, E; Mugabi, T; Kigozi, E; Tukundane, A; Okirwoth, M; Kandole, TK; Cresswel, F; Harrison, T; MOORE, D; Fielding, K; Meya, D; Boulware, D; JARVIS, J;
2024
Wellcome Open Res
Recently activated CD4 T cells in tuberculosis express OX40 as a target for host-directed immunotherapy.
Gress, AR; Ronayne, CE; Thiede, JM; Meyerholz, DK; Okurut, S; Stumpf, J; Mathes, TV; Ssebambulidde, K; Meya, DB; CRESSWELL, FV; Boulware, DR; Bold, TD;
2023
Nature communications
1490. Predictors of Early Mortality in HIV-associated Tuberculous Meningitis
Kagimu, E; Bangdiwala, A; Kasibante, J; Kabahubya, M; Gakuru, J; Timothy, M; Namombwe, S; Kimuda, S; Kasozi, D; Rutakingirwa, MK; Ssebambulidde, K; Tugume, L; Nuwagira, E; Okurut, S; Nsangi, L; Atukunda, M; ELLIS, JP; Williams, DA; Musubire, AK; Boulware, DR; Meya, D; Bahr, NC; CRESSWELL, FV;
2023
Open Forum Infectious Diseases
Advancing Diagnosis and Treatment in People Living with HIV and Tuberculosis Meningitis.
Kimuda, S; Kasozi, D; Namombwe, S; Gakuru, J; Mugabi, T; Kagimu, E; Rutakingirwa, MK; Leon, KE; Chow, F; Wasserman, S; Boulware, DR; CRESSWELL, FV; Bahr, NC;
2023
Current HIV/AIDS reports
Long-acting antiretrovirals: research and implementation considerations in Africa.
NORCROSS, C; Ombajo, LA; Kassim, S; Garrett, N; CRESSWELL, FV; RUZAGIRA, E;
2023
The lancet. HIV
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