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Dr Sharon Cox

Bsc Msc PhD

Associate Professor
Professor of Epidemiology & Nutrition at Nagasaki School of Tropical Medicine & Global Health

School of Tropical Medicine & Global Health
Nagasaki University
Nagasaki,
Japan

Tel.
+44 (0) 207 927 2797

Fax.
+44 (0) 207 958 8111

I graduated from University College London with a BSc. (Biochemistry, First Class Hons) in 1996, followed by a post graduate teaching qualification (1997), a Masters in Public Health Nutrition at LSHTM (1998) and finally a PhD, also at LSHTM (2003). My PhD comprised a clinical trial in Ghana of low-dose maternal vitamin A supplementation to determine effects on immunity to malaria in pregnancy. In 2002 I became a staff member at LSHTM within the MRC International Nutrition Group and worked on malaria and anemia in Gambian children. In 2007 I moved to be based in Dar es Salaam Tanzania, working mostly on sickle cell disease. In 2015 I was appointed as a Professor at the School of Tropical Medicine & Global Health, Nagasaki, where I am now based. I hold a joint position as an Associate Professor at LSHTM. 

Affiliations

Faculty of Epidemiology and Population Health
Department of Population Health

Centres

Centre for Global Chronic Conditions
Malaria Centre
Centre for Maternal Adolescent Reproductive & Child Health (MARCH)
TB Centre

Teaching

I have previously taught and managed units within the MSc in Nutrition for Global Health and I have been a tutor for units on distance based learning MSc courses: ID202 “Nutrition and Infection” (MSc Infectious Diseases) & EPM201 "Study Design: writing a grant application" (MSc Epidemiology). 


In my role at the Nagasaki Graduate School of Tropical Medicine & Global Health, I teach on the three graduate courses; the  MSc in Global Health, Masters in Public Health and MSc in Tropical Medicine. I coordinate the joint teaching in epidemiology and statistics between LSHTM and Nagasaki staff on the above Masters programmes. I also teach sessions on nutrition, research methodology and organise the Nutrition and Global Health module in Semester 3.

Research

Nutrition and Tuberculosis

In collaboration with colleagues in infectious diseases I am conducting research to investigate how nutrition and nutritional management of moderate and severe acute malnutrition and diabetes may determine TB disease outcomes. This includes a study of acutely unwell patients admitted to the TB ward in the Philippines with investigators from the San Lazaro Hospital, Manila. In collaboration with  with the Nutrition Centre Philippines and the Filipino National TB Programme we completed a cross-sectional study in TB patients recieving anti-TB treatment through public TB-DOTS clinics in sites in Manila and rural/semi-rural sites in the Western Visayas Region (ISRCTN12506117). In February 2019 we finsihed recruiting Filipino TB patients (N=902) at the start of treatment with planned follow-up until 2 years post-treatment (ISRCTN16347615). Within this cohort, there are currently  3 Phd student research projects covering health economics, health systems and psychosocial health, supported by expert researchers in these areas at LSHTM and elsewhere. 

Other research areas include:

  • Maternal and child health: focusing on nutrition and infection and effects on growth and anaemia.
  • Long-term effects of severe acute malnutrition (Co-Investigator with Prof Suzanne Filteau on MRC grant - SAMPA, starting Jan 2021)
  • Detection and management of malnutrition in hospitalized children (all ages) and in the community 
  • Sickle cell disease in LMIC

My previous research in sickle cell disease in Tanzaia is outlined below.  


I worked with the Muhimbili Sickle Cohort in Tanzania, comprising over 4,000 patients in routine follow-up  since 2007. My research focussed on nutritional and genetic modulation of sickle cell disease (SCD). We completed a Wellcome Trust funded clinical trial of a nutraceutical intervention in children with SCD with primary endpoints of growth and improved vascular function (ISRCTN74331412);  Cox et al. Lancet Haematology 2018 .  My main collaborators in the Muhimbili Sicke Cohort are Dr Julie Makani, (Muhimbili University of Health & Allied Sciences & University of Oxford) & Professor Charles Newton (University of Oxford & KEMRI-Kilifi, Kenya).

 

 

 

Research Area
Child health
Maternal health
Micronutrients
Global Health
Discipline
Genetic epidemiology
Immunoepidemiology
Biochemistry
Epidemiology
Nutrition
Disease and Health Conditions
Cardiovascular disease
Infectious disease
Malaria
Malnutrition
Tuberculosis
Diabetes
Non-communicable diseases
Tropical diseases
Country
Burundi
The Gambia
India
Japan
Kenya
Cambodia
Myanmar (Burma)
Mongolia
Nepal
Philippines
Tanzania
Vietnam
Region
East Asia & Pacific (all income levels)
South Asia
Sub-Saharan Africa (developing only)

Selected Publications

Effects of comorbidities on quality of life in Filipino people with tuberculosis
Edwards T; White LV; Lee N; Castro MC; Sauldar NR; Faguer BN; Fuente ND; Mayoga F; Ariyoshi K; Garfin AMCG
2020
International Journal of Tuberculosis and Lung Disease
Frequent unregulated use of antibiotics in rural Cambodian infants.
Miyazaki A; Tung R; Taing B; Matsui M; Iwamoto A; Cox SE
2020
Transactions of the Royal Society of Tropical Medicine and Hygiene
Prevalence and risk factors of Schistosoma mansoni infection among children under two years of age in Mbita, Western Kenya.
Sassa M; Chadeka EA; Cheruiyot NB; Tanaka M; Moriyasu T; Kaneko S; Njenga SM; Cox SE; Hamano S
2020
PLoS neglected tropical diseases
Patterns and predictors of co-morbidities in Tuberculosis: A cross-sectional study in the Philippines.
White LV; Edwards T; Lee N; Castro MC; Saludar NR; Calapis RW; Faguer BN; Fuente ND; Mayoga F; Saito N
2020
Scientific reports
Transcranial Doppler and Magnetic Resonance in Tanzanian Children With Sickle Cell Disease.
Kija EN; Saunders DE; Munubhi E; Darekar A; Barker S; Cox TCS; Mango M; Soka D; Komba J; Nkya DA
2019
Stroke
Mid-upper arm circumference predicts death in adult patients admitted to a TB ward in the Philippines: A prospective cohort study.
Lee N; White LV; Marin FP; Saludar NR; Solante MB; Tactacan-Abrenica RJC; Calapis RW; Suzuki M; Saito N; Ariyoshi K
2019
PloS one
Ready-to-use food supplement, with or without arginine and citrulline, with daily chloroquine in Tanzanian children with sickle-cell disease: a double-blind, random order crossover trial.
Cox SE; Ellins EA; Marealle AI; Newton CR; Soka D; Sasi P; Luca Di Tanna G; Johnson W; Makani J; Prentice AM
2018
The Lancet Haematology
Decreased Hepcidin Levels Are Associated with Low Steady-state Hemoglobin in Children With Sickle Cell Disease in Tanzania.
Lee N; Makani J; Tluway F; Makubi A; Armitage AE; Pasricha S-R; Drakesmith H; Prentice AM; Cox SE
2018
EBioMedicine
Population-Based Incidence Rates of First-Ever Stroke in Central Vietnam.
Yamanashi H; Ngoc MQ; Huy TV; Suzuki M; Tsujino A; Toizumi M; Takahashi K; Thiem VD; Anh DD; Anh NTH
2016
PloS one
Effect of Daily Antenatal Iron Supplementation on Plasmodium Infection in Kenyan Women: A Randomized Clinical Trial.
Mwangi MN; Roth JM; Smit MR; Trijsburg L; Mwangi AM; Demir AY; Wielders JPM; Mens PF; Verweij JJ; Cox SE
2015
JAMA
Expression of the iron hormone hepcidin distinguishes different types of anemia in African children.
Pasricha S-R; Atkinson SH; Armitage AE; Khandwala S; Veenemans J; Cox SE; Eddowes LA; Hayes T; Doherty CP; Demir AY
2014
Science translational medicine
See more Publications