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Dr Sharon Cox

Bsc Msc PhD

Associate Professor
Professor of Epidemiology & Nutrition at Nagasaki School of Tropical Medicine & Global Health

School of Tropical Medicine & Global Health
Nagasaki University
Nagasaki,
Japan

Tel.
+44 (0) 207 927 2797

Fax.
+44 (0) 207 958 8111

I graduated from University College London with a BSc. (Biochemistry, First Class Hons) in 1996, followed by a post graduate teaching qualification (1997), a Masters in Public Health Nutrition at LSHTM (1998) and finally a PhD, also at LSHTM (2003). My PhD comprised a clinical trial in Ghana of low-dose maternal vitamin A supplementation to determine effects on immunity to malaria in pregnancy. In 2002 I became a staff member at LSHTM within the MRC International Nutrition Group and worked on malaria and anemia in Gambian children. In 2007 I moved to be based in Dar es Salaam Tanzania, working mostly on sickle cell disease. In 2015 I was appointed as a Professor at the School of Tropical Medicine & Global Health, Nagasaki, where I am now based. I hold a joint position as an Associate Professor at LSHTM. 

Affiliations

Department of Population Health
Faculty of Epidemiology and Population Health

Centres

Malaria Centre
Maternal, Adolescent, Reproductive & Child Health (MARCH)
Tuberculosis (TB) Centre

Teaching

I have previously taught and managed units within the MSc in Nutrition for Global Health and I have been a tutor for units on distance based learning MSc courses: ID202 “Nutrition and Infection” (MSc Infectious Diseases) & EPM201 "Study Design: writing a grant application" (MSc Epidemiology). 


In my role at the Nagasaki Graduate School of Tropical Medicine & Global Health, I am involved in a new MSc in Global Health taught alongside a Masters in Public Health and MSc in Tropical Medicine. I coordinate the joint teaching in epidemiology and statistics between LSHTM and Nagasaki staff on the above Masters programmes. I also teach sessions on epidemiology, research methodology and organise the Nutrition and Global Health module in Semester 3.

Research

Nutrition and Tuberculosis

In collaboration with colleagues in infectious diseases I am conducting research to investigate how nutrition and nutritional management of moderate and severe acute malnutrition and diabetes may determine TB disease outcomes. This includes a study of acutely unwell patients admitted to the TB ward in the Philippines with investigators from the San Lazaro Hospital, Manila. In collaboration with  with the Nutrition Centre Philippines and the Filipino National TB Programme we recently completed a cross-sectional study in TB patients recieving anti-TB treatment through public TB-DOTS clinics in sites in Manila and rural/semi-rural sites in the Western Visayas Region (ISRCTN12506117). In August 2018 we started recruiting Filipino TB patients (N=800) at the start of treatment with planned follow-up until 2 years post-treatment. Within this cohort, there are currently  3 Phd student research projects covering health economics, health systems and psychosocial health, supported by expert researchers in these areas at LSHTM and elsewhere. 

Other research areas include:

  • Maternal and child health: focussing on nutrition and infection and effects on growth and anaemia.
  • Detection and management of malnutrition in hospitalized children (all ages) and in the community 
  • Sickle cell disease in LMIC

My previous research in sickle cell disease in Tanzaia is outlined below.  


I worked with the Muhimbili Sickle Cohort in Tanzania, comprising over 4,000 patients in routine follow-up  since 2007. My research focussed on nutritional and genetic modulation of sickle cell disease (SCD). We completed a Wellcome Trust funded clinical trial of a nutraceutical intervention in children with SCD with primary endpoints of growth and improved vascular function (ISRCTN74331412);  Cox et al. Lancet Haematology 2018 .  My main collaborators in the Muhimbili Sicke Cohort are Dr Julie Makani, (Muhimbili University of Health & Allied Sciences & University of Oxford) & Professor Charles Newton (University of Oxford & KEMRI-Kilifi, Kenya).

 

 

 

Research Area
Child health
Maternal health
Micronutrients
Global Health
Discipline
Genetic epidemiology
Immunoepidemiology
Biochemistry
Epidemiology
Nutrition
Disease and Health Conditions
Cardiovascular disease
Infectious disease
Malaria
Malnutrition
Tuberculosis
Diabetes
Non-communicable diseases
Tropical diseases
Country
Burundi
Gambia, The
India
Japan
Kenya
Cambodia
Mongolia
Nepal
Philippines
Tanzania
Vietnam
Region
East Asia & Pacific (all income levels)
South Asia
Sub-Saharan Africa (developing only)

Selected Publications

Ready-to-use food supplement, with or without arginine and citrulline, with daily chloroquine in Tanzanian children with sickle-cell disease: a double-blind, random order crossover trial.
Cox SE; Ellins EA; Marealle AI; Newton CR; Soka D; Sasi P; Luca Di Tanna G; Johnson W; Makani J; Prentice AM
2018
The Lancet Haematology
Decreased Hepcidin Levels Are Associated with Low Steady-state Hemoglobin in Children With Sickle Cell Disease in Tanzania.
Lee N; Makani J; Tluway F; Makubi A; Armitage AE; Pasricha SR; Drakesmith H; Prentice AM; Cox SE
2018
EBioMedicine
Serum calcium levels, chronic inflammation and glucose metabolism: A cross- sectional analysis in Andhra Pradesh Parents and Children Study (APCaPS)
Shridhar K; Kinra S; Gupta R; Khandelwal S; D P; Cox SE; Dhillon PK
2018
Current Developments in Nutrition
Population-Based Incidence Rates of First-Ever Stroke in Central Vietnam.
Yamanashi H; Ngoc MQ; Huy TV; Suzuki M; Tsujino A; Toizumi M; Takahashi K; Thiem VD; Anh DD; Anh NT
2016
PloS one
Effect of Daily Antenatal Iron Supplementation on Plasmodium Infection in Kenyan Women: A Randomized Clinical Trial.
Mwangi MN; Roth JM; Smit MR; Trijsburg L; Mwangi AM; Demir AY; Wielders JP; Mens PF; Verweij JJ; Cox SE
2015
JAMA
See more Publications