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Professor David Conway

Professor of Biology

United Kingdom

David conducts research on malaria, particularly involving population genetic, experimental and epidemiological studies of parasites. Based in London, he also works with colleagues in several countries in West Africa, as well as in Malaysia. He has served as Associate Dean for Research in the Faculty, and also as Head of Department and as Departmental Research Degrees Coordinator. He was previously Head of Malaria Research Programme at the MRC Unit in The Gambia where he studied many aspects of the disease in relation to natural infection and transmission. Prior to that has also worked on other infectious diseases including trachoma and strongyloidiasis. He studied at the University of Nottingham and University of Edinburgh, and worked at Imperial College London before joining LSHTM.

Affiliations

Department of Infection Biology
Faculty of Infectious and Tropical Diseases

Centres

Malaria Centre
Vaccine Centre

Teaching

Module Organiser for Pathogen Genomics (MSc Module 3460)

Research

Malaria, Parasite Biology, Genomics, Epidemiology, Population Genetics
Research Area
Genetics
Genomics
Epidemiology
Immunology
Disease and Health Conditions
Malaria
Country
Ghana
Gambia
Senegal
Nigeria
Mali
Guinea
Guinea-Bissau
Mauritania
Malaysia
Region
Sub-Saharan Africa (developing only)
East Asia & Pacific (developing only)

Selected Publications

Multiplication rate variation of malaria parasites from hospital cases and community infections.
STEWART, LB; Escolar, EL; Philpott, J; Claessens, A; AMAMBUA-NGWA, A; CONWAY, DJ;
2025
Scientific reports
Expression of the MSPDBL2 antigen in a discrete subset of <i>Plasmodium falciparum</i> schizonts is regulated by GDV1 but may not be linked to sexual commitment.
FREVILLE, A; STEWART, LB; Tetteh, KK A; Treeck, M; Cortes, A; Voss, TS; Tarr, SJ; BAKER, DA; CONWAY, DJ;
2024
mBio
Genomic variation during culture adaptation of genetically complex Plasmodium falciparum clinical isolates.
Claessens, A; STEWART, LB; Drury, E; Ahouidi, AD; AMAMBUA-NGWA, A; Diakite, M; Kwiatkowski, DP; Awandare, GA; CONWAY, DJ;
2023
Microbial genomics
Chloroquine resistance evolution in Plasmodium falciparum is mediated by the putative amino acid transporter AAT1.
AMAMBUA-NGWA, A; Button-Simons, KA; Li, X; Kumar, S; Brenneman, KV; Ferrari, M; Checkley, LA; Haile, MT; Shoue, DA; McDew-White, M; Tindall, SM; Reyes, A; Delgado, E; Dalhoff, H; Larbalestier, JK; Amato, R; Pearson, RD; Taylor, AB; Nosten, FH; D'ALESSANDRO, U; Kwiatkowski, D; Cheeseman, IH; Kappe, SH I; Avery, SV; CONWAY, DJ; ... Anderson, TJ C.
2023
Nature microbiology
Malaria parasite density and detailed qualitative microscopy enhances large-scale profiling of infection endemicity in Nigeria.
Oyibo, W; Latham, V; Oladipo, O; Ntadom, G; Uhomoibhi, P; Ogbulafor, N; Okoronkwo, C; Okoh, F; Mahmoud, A; Shekarau, E; ORESANYA, O; Cherima, YJ; Jalingo, I; Abba, B; Audu, M; CONWAY, DJ;
2023
Scientific reports
Highly Variable Expression of Merozoite Surface Protein MSPDBL2 in Diverse Plasmodium falciparum Clinical Isolates and Transcriptome Scans for Correlating Genes.
Hocking, SE; STEWART, LB; FREVILLE, A; Reid, AJ; Tarr, SJ; TETTEH, KK A; Flueck, C; Ahouidi, AD; AMAMBUA-NGWA, A; Diakite, M; Awandare, GA; CONWAY, DJ;
2022
mBio
Malaria protection due to sickle haemoglobin depends on parasite genotype.
Band, G; Leffler, EM; Jallow, M; Sisay-Joof, F; Ndila, CM; Macharia, AW; Hubbart, C; Jeffreys, AE; Rowlands, K; Nguyen, T; Gonçalves, S; Ariani, CV; Stalker, J; Pearson, RD; Amato, R; Drury, E; Sirugo, G; D'ALESSANDRO, U; BOJANG, KA; Marsh, K; Peshu, N; Saelens, JW; Diakité, M; Taylor, SM; CONWAY, DJ; ... Kwiatkowski, DP.
2021
Nature
A heat-shock response regulated by the PfAP2-HS transcription factor protects human malaria parasites from febrile temperatures.
Tintó-Font, E; Michel-Todó, L; Russell, TJ; Casas-Vila, N; CONWAY, DJ; Bozdech, Z; Llinás, M; Cortés, A;
2021
Nature microbiology
Intrinsic multiplication rate variation and plasticity of human blood stage malaria parasites.
STEWART, LB; Diaz-Ingelmo, O; Claessens, A; Abugri, J; Pearson, RD; Goncalves, S; Drury, E; Kwiatkowski, DP; Awandare, GA; CONWAY, DJ;
2020
COMMUNICATIONS BIOLOGY
Modelling pathogen load dynamics to elucidate mechanistic determinants of host-Plasmodium falciparum interactions.
Georgiadou, A; Lee, HJ; Walther, M; Van Beek, AE; Fitriani, F; Wouters, D; Kuijpers, TW; Nwakanma, D; D'ALESSANDRO, U; Riley, EM; Otto, TD; Ghani, A; Levin, M; Coin, LJ; CONWAY, DJ; Bretscher, MT; Cunnington, AJ;
2019
Nature microbiology
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