Close

Tapan Bhattacharyya

PhD

Research Fellow
: serological diagnostics for protozoal diseases.

Room
Rm 390 (open plan), Rm 347 (lab)

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
0207 927 2319 (office)

Tapan joined LSHTM in 2009.

Molecular epidemiology of Trypanosoma cruzi, agent of Chagas disease. Chagas disease remains an important parasitic infection in the Americas. The vectors for the protozoan agent T. cruzi are triatomine bugs, which transmit the infective stage of the parasite in their faeces when taking a blood-meal. T. cruzi is classified into genetic lineages TcI-TcVI exhibiting a complex geographical distribution and a poorly understood relationship to clinical symptoms. My work is directed towards furthering understanding of the epidemiology of the different parasite lineages in this neglected tropical disease.

Serological diagnostics for Leishmania donovani, agent of visceral leishmaniasis. Visceral leishmaniasis, caused by infection with protozoa of the Leishmania donovani complex, remains a major public health problem in endemic regions of South Asia, East Africa, and Brazil. Phlebotomus and Lutzomyia sandflies are vectors in the Old and New World, respectively. My work is directed toward comparing and improving serological tests across endemicities, including identifying novel antigens.

Affiliations

Faculty of Infectious and Tropical Diseases
Department of Infection Biology

Teaching

Supervision of Masters student summer research projects (Asia, Africa, South America)

Lecturer: Advanced Diagnostic Parsitology module

 

 

Research

Research Area
Diagnostics
Parasites
Trypanosomes
Protozoa
Discipline
Genetic epidemiology
Immunoepidemiology
Molecular epidemiology
Immunology
Microbiology
Molecular biology
Parasitology
Disease and Health Conditions
Leishmaniasis
Chagas Disease
Neglected Tropical Diseases (NTDs)
Tropical diseases
Region
World

Selected Publications

Refining wet lab experiments with in silico searches: A rational quest for diagnostic peptides in visceral leishmaniasis.
Bremer Hinckel BC; Marlais T; Airs S; Bhattacharyya T; Imamura H; Dujardin J-C; El-Safi S; Singh OP; Sundar S; Falconar AK
2019
PLoS neglected tropical diseases
Severity of Chagasic Cardiomyopathy Is Associated With Response To A Novel Rapid Diagnostic Test For Trypanosoma cruzi TcII/V/VI.
Bhattacharyya T; Messenger LA; Bern C; Mertens P; Gilleman Q; Zeippen N; Bremer Hinckel BC; Murphy N; Gilman RH; Miles MA
2018
Clinical infectious diseases
Detection of IgG1 against rK39 improves monitoring of treatment outcome in visceral leishmaniasis
Mollet G; Bremer Hinckel BC; Bhattacharyya T; Marlais T; Singh OP; Mertens P; Falconar A; El-Safi S; Sundar S; Miles M
2018
Clinical Infectious Diseases
Visceral leishmaniasis IgG1 rapid monitoring of cure versus relapse, and potential for diagnosis of post kala-azar dermal leishmaniasis
Marlais T; Bhattacharyya T; Singh OP; Mertens P; Gilleman Q; 18 Others; Miles M
2018
Frontiers in Cellular and Infection Microbiology
Diagnostic antigens for visceral leishmaniasis: clarification of nomenclatures.
Bhattacharyya T; Marlais T; Miles MA
2017
Parasites & vectors
Significantly Lower Anti-Leishmania IgG Responses in Sudanese versus Indian Visceral Leishmaniasis.
Bhattacharyya T; Bowes DE; El-Safi S; Sundar S; Falconar AK; Singh OP; Kumar R; Ahmed O; Boelaert M; Miles MA
2014
PLoS neglected tropical diseases
IgG1 as a Potential Biomarker of Post-chemotherapeutic Relapse in Visceral Leishmaniasis, and Adaptation to a Rapid Diagnostic Test.
Bhattacharyya T; Ayandeh A; Falconar AK; Sundar S; El-Safi S; Gripenberg MA; Bowes DE; Thunissen C; Singh OP; Kumar R
2014
PLoS neglected tropical diseases
Development of Peptide-based lineage-specific serology for chronic chagas disease: geographical and clinical distribution of epitope recognition.
Bhattacharyya T; Falconar AK; Luquetti AO; Costales JA; Grijalva MJ; Lewis MD; Messenger LA; Tran TT; Ramirez JD; Guhl F
2014
PLoS neglected tropical diseases
Multiple Mitochondrial Introgression Events and Heteroplasmy in Trypanosoma cruzi Revealed by Maxicircle MLST and Next Generation Sequencing.
Messenger LA; Llewellyn MS; Bhattacharyya T; Franzén O; Lewis MD; Ramírez JD; Carrasco HJ; Andersson B; Miles MA
2012
PLoS neglected tropical diseases
See more Publications