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Tapan Bhattacharyya

PhD

Research Fellow
: serological diagnostics for protozoal diseases.

Room
Rm 390 (open plan), Rm 347 (lab)

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

Tel.
0207 927 2319 (office)

Tapan joined LSHTM in 2009.

Molecular epidemiology of Trypanosoma cruzi, agent of Chagas disease. Chagas disease remains an important parasitic infection in the Americas. The vectors for the protozoan agent T. cruzi are triatomine bugs, which transmit the infective stage of the parasite in their faeces when taking a blood-meal. T. cruzi is classified into genetic lineages TcI-TcVI exhibiting a complex geographical distribution and a poorly understood relationship to clinical symptoms. My work is directed towards furthering understanding of the epidemiology of the different parasite lineages in this neglected tropical disease.

Serological diagnostics for Leishmania donovani, agent of visceral leishmaniasis. Visceral leishmaniasis, caused by infection with protozoa of the Leishmania donovani complex, remains a major public health problem in endemic regions of South Asia, East Africa, and Brazil. Phlebotomus and Lutzomyia sandflies are vectors in the Old and New World, respectively. My work is directed toward comparing and improving serological tests across endemicities, including identifying novel antigens.

Affiliations

Faculty of Infectious and Tropical Diseases
Department of Pathogen Molecular Biology

Teaching

M3333 Molecular biology module: Lecture; organiser of laboratory practical.

Supervision of Masters student summer research projects (Asia, Africa, South America)

Personal Tutor for MSc Control of Infectious Diseases

Research

Research Area
Diagnostics
Parasites
Trypanosomes
Protozoa
Discipline
Genetic epidemiology
Immunoepidemiology
Molecular epidemiology
Immunology
Microbiology
Molecular biology
Parasitology
Disease and Health Conditions
Leishmaniasis
Chagas Disease
Neglected Tropical Diseases (NTDs)
Tropical diseases
Region
World

Selected Publications

Severity of Chagasic Cardiomyopathy Is Associated With Response To A Novel Rapid Diagnostic Test For Trypanosoma cruzi TcII/V/VI.
Bhattacharyya, T. ; Messenger, L.A. ; Bern, C. ; Mertens, P. ; Gilleman, Q. ; Zeippen, N. ; Bremer Hinckel, B.C. ; Murphy, N. ; Gilman, R.H. ; Miles, M.A. ; Chagas Working Group in Bolivia and Peru, . ;
2018
Clin Infect Dis
Diagnostic antigens for visceral leishmaniasis: clarification of nomenclatures.
Bhattacharyya, T. ; Marlais, T. ; Miles, M.A. ;
2017
Parasit Vectors
Significantly Lower Anti-Leishmania IgG Responses in Sudanese versus Indian Visceral Leishmaniasis.
Bhattacharyya, T. ; Bowes, D.E. ; El-Safi, S. ; Sundar, S. ; Falconar, A.K. ; Singh, O.P. ; Kumar, R. ; Ahmed, O. ; Boelaert, M. ; Miles, M.A. ;
2014
PLoS Negl Trop Dis
Development of Peptide-based lineage-specific serology for chronic chagas disease: geographical and clinical distribution of epitope recognition.
Bhattacharyya, T. ; Falconar, A.K. ; Luquetti, A.O. ; Costales, J.A. ; Grijalva, M.J. ; Lewis, M.D. ; Messenger, L.A. ; Tran, T.T. ; Ramirez, J.D. ; Guhl, F. ; Carrasco, H.J. ; Diosque, P. ; Garcia, L. ; Litvinov, S.V. ; Miles, M.A. ;
2014
PLoS Negl Trop Dis
IgG1 as a Potential Biomarker of Post-chemotherapeutic Relapse in Visceral Leishmaniasis, and Adaptation to a Rapid Diagnostic Test.
Bhattacharyya, T. ; Ayandeh, A. ; Falconar, A.K. ; Sundar, S. ; El-Safi, S. ; Gripenberg, M.A. ; Bowes, D.E. ; Thunissen, C. ; Singh, O.P. ; Kumar, R. ; Ahmed, O. ; Eisa, O. ; Saad, A. ; Silva Pereira, S. ; Boelaert, M. ; Mertens, P. ; Miles, M.A. ;
2014
PLoS Negl Trop Dis
Multiple Mitochondrial Introgression Events and Heteroplasmy in Trypanosoma cruzi Revealed by Maxicircle MLST and Next Generation Sequencing.
Messenger, L.A. ; Llewellyn, M.S. ; Bhattacharyya, T. ; Franzén, O. ; Lewis, M.D. ; Ramírez, J.D. ; Carrasco, H.J. ; Andersson, B. ; Miles, M.A. ;
2012
PLoS Negl Trop Dis
See all Tapan Bhattacharyya's Publications