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Dr Edwin Armitage

BMBS MSc DTM&H DFPH

Research Fellow
in Global Health

LSHTM
Keppel Street
London
WC1E 7HT
United Kingdom

I am a public health specialty registrar currently funded by the Wellcome Trust as a clinical PhD fellow in Global Health at LSHTM. My PhD is based in The Gambia investigating Group A Streptococcal (StrepA) skin and throat carriage and its relationship to disease. I am conducting a longitudinal household cohort study with frequent microbiological sampling to understand the importance of StrepA carriage in sub-Saharan Africa, and how carriage infleunces StrepA disease. I will also use whole genome sequencing of StrepA isolates to gather to serotype strains and identify transmission events in order to build a mathematical model of within and between household StrepA transmission.

I previously worked for 2 years at the MRC Unit The Gambia on a trial looking at intranasal live attenuated influenza vaccine in children, where I gained experience conducting studies in low-resource settings. I developed an interest in StrepA during that time due to noticing a significant burden of StrepA skin disease in children combined with paradoxically low pharyngitis rates, yet a huge amount of morbidity and mortality from rheumatic heart disease (RHD) in The Gambia. From there I conducted a cross-sectional prevalence study of scabies and StrepA skin disease in children in The Gambia showing a high burden of disease and a marked seasonal increase in bacterial skin infections.

I am working with my supervisors Dr Michael Marks at LSHTM, Dr Thushan de Silva at University of Sheffield, and Dr Adam Kucharski at LSHTM. I am also part of the MRC Unit The Gambia Group A Streptococcal Research Group, where I hope to continue my collaborations with other colleagues, and broaden my research interests and experience.

Affiliations

Department of Clinical Research
MRC - Gambia
Faculty of Infectious and Tropical Diseases

Teaching

I currently have no teaching responsibilities

Research

Group A Streptococcus: Epidemiology and transmission of carriage and disease in The Gambia.

Research Area
Infectious disease policy
Public health
Vaccines
Disease control
Global Health
Immunisation
Randomised controlled trials
Modelling
Discipline
Molecular epidemiology
Bacteriology
Epidemiology
Medicine
Microbiology
Mathematical modelling
Disease and Health Conditions
Infectious disease
Influenza
Neglected Tropical Diseases (NTDs)
Skin disease
Tropical diseases
Scabies
Country
The Gambia
Region
Sub-Saharan Africa (developing only)

Selected Publications

Comparative genomic analysis of skin and soft tissue Streptococcus pyogenes isolates from low- and high-income settings
Bah SY; Keeley AJ; Armitage EP; Khalid H; Chaudhuri RR; Senghore E; Manneh J; Tilley L; Marks M; Darboe S
2021
Molecular Epidemiology of Group A Streptococcus Infections in The Gambia.
Jabang S; Erhart A; Darboe S; Baldeh A-K; Delforge V; Watson G; Foster-Nyarko E; Salaudeen R; Lawal B; Mackenzie G
2021
Vaccines
The effect of live attenuated influenza vaccine on pneumococcal colonisation densities among children aged 24–59 months in The Gambia: a phase 4, open label, randomised, controlled trial
Peno C; Armitage EP; Clerc M; Balcazar Lopez C; Jagne YJ; Drammeh S; Jarju S; Sallah H; Senghore E; Lindsey BB
2021
The Lancet Microbe
Estimation of seasonal influenza attack rates and antibody dynamics in children using cross-sectional serological data.
Minter A; Hoschler K; Jagne YJ; Sallah H; Armitage E; Lindsey B; Hay JA; Riley S; de Silva TI; Kucharski A
2020
The Journal of infectious diseases
High burden and seasonal variation of paediatric scabies and pyoderma prevalence in The Gambia: A cross-sectional study.
Armitage EP; Senghore E; Darboe S; Barry M; Camara J; Bah S; Marks M; Cerami C; Roca A; Antonio M
2019
PLoS neglected tropical diseases
Effect of a Russian-backbone live-attenuated influenza vaccine with an updated pandemic H1N1 strain on shedding and immunogenicity among children in The Gambia: an open-label, observational, phase 4 study.
Lindsey BB; Jagne YJ; Armitage EP; Singanayagam A; Sallah HJ; Drammeh S; Senghore E; Mohammed NI; Jeffries D; Höschler K
2019
The Lancet. Respiratory medicine
Acceptability of intranasal live attenuated influenza vaccine, influenza knowledge and vaccine intent in The Gambia.
Armitage EP; Camara J; Bah S; Forster AS; Clarke E; Kampmann B; de Silva TI
2018
VACCINE
The efficacy, effectiveness, and immunogenicity of influenza vaccines in Africa: a systematic review.
Lindsey BB; Armitage EP; Kampmann B; de Silva TI
2018
The Lancet. Infectious diseases
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