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Interventions to improve water quality for preventing diarrhoea: systematic review and meta-analysis.

BMJ, 2007; 334(7597):782
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Centre for Global Non-Communicable Diseases (NCDs)

pub_id
17353208
pubmedid
17353208
ISI
246037300028
reference_type
author
Clasen, T.; Schmidt, W.P.; Rabie, T.; Roberts, I.; Cairncross, S.;
title
Interventions to improve water quality for preventing diarrhoea: systematic review and meta-analysis.
secondary_title
BMJ
ISBNISSN
0959-8138
volume
334
number
7597
pages
782
year
2007
abstract
OBJECTIVE: To assess the effectiveness of interventions to improve the microbial quality of drinking water for preventing diarrhoea. DESIGN: Systematic review. DATA SOURCES: Cochrane Infectious Diseases Group's trials register, CENTRAL, Medline, Embase, LILACS; hand searching; and correspondence with experts and relevant organisations. STUDY SELECTION: Randomised and quasirandomised controlled trials of interventions to improve the microbial quality of drinking water for preventing diarrhoea in adults and in children in settings with endemic disease. DATA EXTRACTION: Allocation concealment, blinding, losses to follow-up, type of intervention, outcome measures, and measures of effect. Pooled effect estimates were calculated within the appropriate subgroups. DATA SYNTHESIS: 33 reports from 21 countries documenting 42 comparisons were included. Variations in design, setting, and type and point of intervention, and variations in defining, assessing, calculating, and reporting outcomes limited the comparability of study results and pooling of results by meta-analysis. In general, interventions to improve the microbial quality of drinking water are effective in preventing diarrhoea. Effectiveness was not conditioned on the presence of improved water supplies or sanitation in the study setting and was not enhanced by combining the intervention with instructions on basic hygiene, a water storage vessel, or improved sanitation or water supplies--other common environmental interventions intended to prevent diarrhoea. CONCLUSION: Interventions to improve water quality are generally effective for preventing diarrhoea in all ages and in under 5s. Significant heterogeneity among the trials suggests that the level of effectiveness may depend on a variety of conditions that research to date cannot fully explain.
keywords
secondary_author
place_published
publisher
number_of_volumes
tertiary_author
tertiary_title
edition
date
2007-03-12
type_of_work
subsidiary_author
alternate_title
call_number
accession_number
custom_1
WOS OK
custom_2
Unknown
custom_3
custom_4
10.1136/bmj.39118.489931.BE
custom_5
PMC
custom_6
10
label
2016-10-18
notes
Journal Article
url
author_address
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London WC1E 7HT. thomas.clasen@lshtm.ac.uk
library
bmj.39118.489931.BE 10.1136/bmj.39118.489931.BE 17353208
date_accepted
date_online
created
2007-03-15 12:16:11
modified
2016-07-08 00:00:00
library
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<ArticleId IdType="doi">10.1136/bmj.39118.489931.BE</ArticleId>
<ArticleId IdType="pubmed">17353208</ArticleId>