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Handwashing and risk of respiratory infections: a quantitative systematic review.

Trop Med Int Health, 2006; 11(3):258-67
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pub_id
16553905
pubmedid
16553905
ISI
235843200002
reference_type
author
Rabie, T.; Curtis, V.;
title
Handwashing and risk of respiratory infections: a quantitative systematic review.
secondary_title
Trop Med Int Health
ISBNISSN
1360-2276
volume
11
number
3
pages
258-67
year
2006
abstract
OBJECTIVE: To determine the effect of handwashing on the risk of respiratory infection. METHODS: We searched PubMed, CAB Abstracts, Embase, Web of Science, and the Cochrane library for articles published before June 2004 in all languages. We had searched reference lists of all primary and review articles. Studies were included in the review if they reported the impact of an intervention to promote hand cleansing on respiratory infections. Studies relating to hospital-acquired infections, long-term care facilities, immuno-compromised and elderly people were excluded. We independently evaluated all studies, and inclusion decisions were reached by consensus. From a primary list of 410 articles, eight interventional studies met the eligibility criteria. RESULTS: All eight eligible studies reported that handwashing lowered risks of respiratory infection, with risk reductions ranging from 6% to 44% [pooled value 24% (95% CI 6-40%)]. Pooling the results of only the seven homogenous studies gave a relative risk of 1.19 (95% CI 1.12%-1.26%), implying that hand cleansing can cut the risk of respiratory infection by 16% (95% CI 11-21%). CONCLUSIONS: Handwashing is associated with lowered respiratory infection. However, studies were of poor quality, none related to developing countries, and only one to severe disease. Rigorous trials of the impact of handwashing on acute respiratory tract infection morbidity and mortality are urgently needed, especially in developing countries.
keywords
secondary_author
place_published
publisher
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tertiary_title
edition
date
type_of_work
subsidiary_author
alternate_title
call_number
accession_number
custom_1
WOS OK
custom_2
Unknown
custom_3
custom_4
10.1111/j.1365-3156.2006.01568.x
custom_5
Free
custom_6
10
label
2016-10-18
notes
Journal Article
url
author_address
Department of Infectious and Tropical Diseases, The Hygiene Centre, London School of Hygiene and Tropical Medicine, London, UK.
library
TMI1568 10.1111/j.1365-3156.2006.01568.x 16553905
date_accepted
date_online
created
2006-03-27 10:38:12
modified
2016-07-08 00:00:00
library

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