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Factors associated with rotavirus diarrhoea in children living in a socially diverse urban centre in Brazil

Strina, A.; Rodrigues, L. C.; Cairncross, S.; Ferrer, S. R.; Fialho, A. M.; Leite, J. P. G.; Ribeiro, H. C.; Barreto, M. L.
Transactions of the Royal Society of Tropical Medicine and Hygiene, 2012; 106(7):445-451
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Centre for Maternal, Reproductive and Child Health (MARCH)
Centre for Global Non-Communicable Diseases (NCDs)

pub_id
22657535
pubmedid
22657535
ISI
306195100009
reference_type
Journal Article
author
Strina, A.; Rodrigues, L. C.; Cairncross, S.; Ferrer, S. R.; Fialho, A. M.; Leite, J. P. G.; Ribeiro, H. C.; Barreto, M. L.
title
Factors associated with rotavirus diarrhoea in children living in a socially diverse urban centre in Brazil
secondary_title
Transactions of the Royal Society of Tropical Medicine and Hygiene
ISBNISSN
0035-9203
volume
106
number
7
pages
445-451
year
2012
abstract
A case-control study, aimed at identifying factors associated with rotavirus diarrhoea cases presenting to health facilities, was conducted in children from low-income and middle-low-income families in Brazil. Cases were 390 children with diarrhoea and rotavirus in stools; controls were 1674 children without diarrhoea presenting to the same facilities. Data were collected by questionnaire and observations during home visits. Explanatory variables were grouped according to a conceptual model of causation. The ORs by non-conditional logistic regression and population-attributable fractions were calculated. Socioeconomic factors contributed a third of cases, followed by contact with diarrhoea cases and by not being breast fed. In cases aged <1 year, not being breast fed was the main determinant, followed by socioeconomic factors, and crowding and contact outside the home; in older children, socioeconomic factors followed by contact inside and outside the home were the main determinants. Environmental and sanitation variables were not associated with diarrhoea in the final model, and socioeconomic factors were only partly mediated by proximal variables. Transmission of rotavirus appears to be mostly by person-to-person contact, and shows marked social differentials not explained by the biological factors studied. The rotavirus vaccine is unlikely to protect against the full range of circulating genotypes of rotavirus, and understanding rotavirus epidemiology remains essential to the development of control policies. (C) 2012 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.
keywords
Rotavirus Diarrhoea Children Risk factors Brazil group-a rotavirus infectious intestinal disease risk-factors childhood diarrhea protective factors sao-paulo gastroenteritis vaccine hospitalization adenovirus
secondary_author
place_published
publisher
number_of_volumes
tertiary_author
tertiary_title
edition
date
Jul
type_of_work
Article
subsidiary_author
alternate_title
Trans Roy Soc Trop Med Hyg
call_number
accession_number
WOS:000306195100009
custom_1
WOS_OK
custom_2
Unknown
custom_3
custom_4
10.1016/j.trstmh.2012.02.001
custom_5
Subscription Required
custom_6
10
label
2016-11-10
notes
ISI Document Delivery No.: 971HP Times Cited: 0 Cited Reference Count: 36 Strina, Agostino Rodrigues, Laura C. Cairncross, Sandy Ferrer, Suzana R. Fialho, Alexandre Madi Leite, Jose Paulo G. Ribeiro, Hugo C., Jr. Barreto, Mauricio L. Programa de Nucleos de Excelencia (PRONEX/CNPq, Federal Ministry of Science and Technology, Brazil)[661086/1998-4] Financial support for the study was provided by Programa de Nucleos de Excelencia (PRONEX/CNPq, Federal Ministry of Science and Technology, Brazil), Contract No. 661086/1998-4. Elsevier science inc New york
url
://WOS:000306195100009 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22657535
author_address
[Strina, Agostino; Ferrer, Suzana R.; Barreto, Mauricio L.] Univ Fed Bahia, Inst Saude Colet, BR-40110040 Salvador, BA, Brazil. [Rodrigues, Laura C.] London Sch Hyg & Trop Med, Dept Epidemiol & Populat Hlth, London WC1, England. [Cairncross, Sandy] London Sch Hyg & Trop Med, Dept Infect & Trop Dis, London WC1, England. [Ferrer, Suzana R.] Escola Bahiana Med & Saude Publ, Salvador, BA, Brazil. [Fialho, Alexandre Madi; Leite, Jose Paulo G.] Minist Hlth, Oswaldo Cruz Fdn, Lab Comparat & Environm Virol, Rio De Janeiro, RJ, Brazil. [Ribeiro, Hugo C., Jr.] Univ Fed Bahia, Dept Pediat, Sch Med, Salvador, BA, Brazil. Strina, A (reprint author), Univ Fed Bahia, Inst Saude Colet, Rua Basilio da Gama S-N Canela, BR-40110040 Salvador, BA, Brazil. agstrina@yahoo.com.br
library
S0035-9203(12)00026-0 10.1016/j.trstmh.2012.02.001 22657535
date_accepted
date_online
created
2012-09-17 16:01:45
modified
2016-07-08 00:00:00
library

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<ArticleId IdType="doi">10.1016/j.trstmh.2012.02.001</ArticleId>
<ArticleId IdType="pubmed">22657535</ArticleId>