Diana Elbourne PhD

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Background

Diana graduated in Social Administration from the London School of Economics in 1971. She worked as a part-time lecturer in Statistics in Brunel University between 1974 and 1981, while studying for her MSc (Stats) which she received in 1979. In 1981 she became Social Statistician at the National Perinatal Epidemiology Unit (NPEU) in Oxford. A randomised controlled trial (RCT) about women holding their own obstetric records formed the basis for her PhD, awarded in 1989. In 1990, she was appointed Deputy Director of the Perinatal Trials Service (PTS) in the NPEU, co-ordinating a series of multicentre RCTs in the perinatal field, and conducting associated methodological research. She took over as Honorary Director of the PTS in 1994.

She joined the Medical Statistics Unit at LSHTM in 1997, and was appointed Professor of Healthcare Evaluation in March 2002. She was Unit Head from 1998 to 2004. Between 2000 and 2004, she held a half-time appointment as Chair in Evidence Informed Policy and Practice at the Social Science Research Unit in the Institute of Education (University of London).

She now works half time - usually Tuesdays, Wednesdays, and Thursday afternoons

Teaching

Her main teaching interests are in clinical trials, in particular on the Short Course in Clinical Trials each September (http://www.lshtm.ac.uk/prospectus/short/sct.html), and the distance learning MSc in Clinical Trials which started in September 2006 (see http://www.lshtm.ac.uk/prospectus/masters/dmsct.html)

Research

Her main research interests are in RCTs, systematic reviews, qualitative studies of the views of participants in trials, reporting of trials, data monitoring committees, and cluster RCTs. She applies these interest in various fields, currently including maternal and child health, intensive care (of newborn babies, children and adults), and care of the elderly.

Selected publications

• Piaggio, G.; Elbourne, D.R.; Altman, D.G.; Pocock, S.J.; Evans, S.J.; Reporting of noninferiority and equivalence randomized trials: an extension of the CONSORT statement. JAMA, 2006; 295(10):1152-60
• Snowdon, C.; Elbourne, D.; Garcia, J.; "It was a snap decision": Parental and professional perspectives on the speed of decisions about participation in perinatal randomised controlled trials. Soc Sci Med, 2006; 62(9):2279-90
• McNally, H.; Bennett, C.C.; Elbourne, D.; Field, D.J.; United Kingdom collaborative randomized trial of neonatal extracorporeal membrane oxygenation: follow-up to age 7 years. Pediatrics, 2006; 117(5):e845-54
• Field, D.; Elbourne, D.; Hardy, P.; Fenton, A.C.; Ahluwalia, J.; Halliday, H.L.; Subhedar, N.; Heinonen, K.; Aikio, O.; Grieve, R.; Truesdale, A.; Tomlin, K.; Normand, C.; Stocks, J.; Neonatal Ventilation with Inhaled Nitric Oxide vs. Ventilatory Support without Inhaled Nitric Oxide for Infants with Severe Respiratory Failure Born at or Near Term: The INNOVO Multicentre Randomised Controlled Trial. Neonatology, 2007; 91(2):73-82
• Harvey, S.E.; Elbourne, D.; Ashcroft, J.; Jones, C.M.; Rowan, K.; Informed consent in clinical trials in critical care: experience from the PAC-Man Study. Intensive Care Med, 2006; 32(12):2020-5
• Moher, D.; Schultz, K. F.; Altman, D. G.; For The Consort Group (Including Elbourne, D., Pocock, S.) The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomized trials Annals of Internal Medicine, 2001; 134(8):657-62
• Gulmezoglu, A. M.; Villar, J.; Ngoc, N. T. N.; Piaggio, G.; Carroli, G.; Adetoro, L.; Abdel-Aleem, H.; Cheng, L. N.; Hofmeyr, G. J.; Lumbiganon, P.; Unger, C.; Prendiville, W.; Pinol, A.; Elbourne, D.; el-Refaey, H.; Schulz, K. F. WHO multicentre randomised trial of misoprostol in the management of the third stage of labour Lancet, 2001; 358(9283):689-95
• Snowdon, C.; Elbourne, D.; Garcia, J.; Campbell, M.K.; Entwistle, V.A.; Francis, D.; Grant, A.M.; Knight, R.C.; McDonald, A.M.; Roberts, I.; Financial considerations in the conduct of multi-centre randomised controlled trials: evidence from a qualitative study. Trials, 2006; 7(1):34

Full publications listing (since 2001)